Acute Eosinophilic Pneumonia Associated With the Anti-COVID-19 Vaccine AZD1222Allergy/Immunology Published on 2021-10-212022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress Acute respiratory failure allergenic allergies allergy Antibiotics AstraZeneca AZD1222 cause ChAdOx1 nCoV-19 Corticosteroid Corticosteroids described eosinophilia eosinophilic pneumonia eosinophils global pandemic Hypereosinophilia Influenza lack less male outcome Patient pneumococcal Pneumonia polysaccharide vaccine post-COVID-19 vaccination postvaccination prevented reaction Reactions retained SARS-CoV-2 vaccination Vaccine virus [DOI] 10.7759/cureus.18959 PMC 바로가기 [Article Type] Allergy/Immunology
Nutrition Supports Deconstructed and Disrupted: An Evaluation of a Multilevel School-Based Intervention during the Time of COVIDArticle Published on 2021-10-202022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] analyzed assistance benefit COVID COVID-19 decrease Evaluation family food Food security Forward groups Health health inequities IMPROVE increase in indicated Intervention less low income nutrition observation outcome parent participant postintervention preintervention prevented Program random Rate reported Schools screenings significant decrease significant difference significantly Support time [DOI] 10.3390/ijerph182111006 PMC 바로가기 [Article Type] Article
In Vitro Effect of Taraxacum officinale Leaf Aqueous Extract on the Interaction between ACE2 Cell Surface Receptor and SARS-CoV-2 Spike Protein D614 and Four MutantsArticle Published on 2021-10-172022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] ACE2 ACE2 binding inhibitor ACE2 receptor applicability aqueous B.1.617.2 Compound COVID-19 D614G dandelion Delta E484K Effect Efficacy Extract form human ACE2 receptor Immune escape in vitro result K417N kidney leaf lentivirus lung cell lung cells multiple mutation mutant N501Y new SARS-CoV-2 Non-invasive Particle prevented pro-inflammatory Prophylaxis Protein–protein interaction pseudotyped reported Research S1 spike mutation Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 prevention SARS-CoV-2 spike secretion sequence shown spike surface Taraxacum officinale the spike protein variant wild type Wuhan [DOI] 10.3390/ph14101055 PMC 바로가기 [Article Type] Article
Emotional distress in the early stages of the COVID-19 related lockdowns depending on the severity of the pandemic and emergency measures: a comparative online-survey in Germany, Austria and ItalyResearch Published on 2021-10-152022-10-27 Journal: BMC Psychiatry [Category] COVID-19, [키워드] assumed country Course COVID-19 COVID-19 virus dimension disease distress early phase early stage effective Emergency measures emotional First wave Germany Government individuals investigated Italian Italy less lockdown measure Measures negative objective online survey pandemic participant Perceived risk positive Prevalence prevented Psychological questionnaire Result risk schedule severity severity of COVID-19 significant difference Stress supplementary material turn virus [DOI] 10.1186/s12888-021-03505-7 PMC 바로가기 [Article Type] Research
Emotional distress in the early stages of the COVID-19 related lockdowns depending on the severity of the pandemic and emergency measures: a comparative online-survey in Germany, Austria and ItalyResearch Published on 2021-10-152022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] assumed country Course COVID-19 COVID-19 virus dimension disease distress early phase early stage effective Emergency measures emotional First wave Germany Government individuals investigated Italian Italy less lockdown measure Measures negative objective online survey pandemic participant Perceived risk positive Prevalence prevented Psychological questionnaire Result risk schedule severity severity of COVID-19 significant difference Stress supplementary material turn virus [DOI] 10.1186/s12888-021-03505-7 PMC 바로가기 [Article Type] Research
Nasal delivery of single-domain antibody improves symptoms of SARS-CoV-2 infection in an animal model단일 도메인 항체의 비강 전달은 동물 모델에서 SARS-CoV-2 감염의 증상을 개선합니다Research Article Published on 2021-10-142022-09-10 Journal: PLoS Pathogens [Category] MERS, SARS, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration alveolar amplified animal model antibody Behavior block blood stream can not cause caused Cell cells conditions coronavirus COVID-19 COVID-19 patients cryo Cryo-electron microscopy cytokine demonstrated drug drug candidates electron microscopy fusing hamster hamsters host cell host cell membrane human lung organoids immune reaction IMPROVE in vitro infected cell infected cells infective inhibited lead less life-threatening lung Medical conditions membrane Microscopy N-terminal domain nasal nebulizer neutralize neutralized nose occur potency Prevent prevented produced progeny receptor Receptor binding domain reducing Reinfection respiratory risk S protein SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe pneumonia Symptom Symptoms the disease therapeutic drug TMPRSS2 treat treated Treatment typical symptom typical symptoms Vaccine Viral viral membrane virus weight loss while [DOI] 10.1371/journal.ppat.1009542 PMC 바로가기 [Article Type] Research Article
Leveraging HIV Care Infrastructures for Integrated Chronic Disease and Pandemic Management in Sub-Saharan AfricaPerspective Published on 2021-10-132022-10-30 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] African AIDS approach build Cancer cardiovascular disease Care chronic communicable Community COVID-19 Critical Depression diabetes Emergency Epidemic health system health system strengthening healthcare HIV HIV/AIDS implementation Infectious disease Infectious diseases Infrastructure integrated care Non-communicable disease non-communicable diseases pandemic Prevalence prevented Recognition recommendation relief Research response South sub-Saharan Africa Support Threats treated tropical Tuberculosis with COVID-19 with HIV [DOI] 10.3390/ijerph182010751 PMC 바로가기 [Article Type] Perspective
Molecular testing and analysis of disease spreading during the emergence of COVID-19 in Macaé, the Brazilian National Capital of Oil브라질 국립 석유 자본 인 마카에 (Macaé)에서 Covid-19가 출현하는 동안 질병 확산의 분자 검사 및 분석Observational Study Published on 2021-10-112022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, [키워드] administration Analysis approach Brazil Capital catastrophic city Cluster cluster analysis consequence contributed COVID-19 COVID-19 transmission described disease effort Engagement epidemiological Evolution fatality FIVE genetics Governance joint lack limit Local local administration molecular Molecular biology National Oil outbreak overcome pandemic PCR-based techniques positive individual positive individuals prevented quarantine recorded Rio de Janeiro RT-qPCR Spread spread of COVID-19 Swab Symptom Transmission university viral infection were used with COVID-19 [DOI] 10.1038/s41598-021-99475-7 PMC 바로가기 [Article Type] Observational Study
Highly susceptible SARS-CoV-2 model in CAG promoter–driven hACE2-transgenic miceCAG 프로모터 구동 hACE2 형질전환 마우스에서 매우 민감한 SARS-CoV-2 모델Resource and Technical Advance Published on 2021-10-082022-09-12 Journal: JCI Insight [Category] MERS, SARS, 진단, [키워드] acute lung injury angiotensin Angiotensin-converting enzyme animal model animal models body weight Body weight loss CAG caused chemokine Consequences COVID-19 cytokine death develop early stage elevated enzyme Genome hACE2 human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 immunization immunized mice infected with SARS-CoV-2 Infection infection with SARS-CoV-2 injection lethality Lung injury Medicines mice Mouse models pathogenicity plasma prevented SARS-CoV-2 SARS-COV-2 infection severe symptom Spread subsequent susceptibility susceptible tandem therapeutic Therapeutics Vaccine Viral antigen weight loss [DOI] 10.1172/jci.insight.152529 PMC 바로가기 [Article Type] Resource and Technical Advance
Inhibition of SARS-CoV-2 Replication by a Small Interfering RNA Targeting the Leader Sequence리더 서열을 표적으로하는 작은 간섭 RNA에 의한 SARS-COV-2 복제의 억제Article Published on 2021-10-082022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, 신약개발, 진단, 치료제, [키워드] 5′-UTR 5′-untranslated region 5′-UTR acute respiratory syndrome acute respiratory syndrome coronavirus Alpha analyzed assays conserved coronavirus COVID-19 Cytopathic effect death delta variant eight family member genomic highly active homology inhibition initial leader sequence magnitude means prevented reduced replication Replication reporter respiratory retained RNA RNA interference RNAi RNAi therapy SARS-CoV virus SARS-CoV viruses SARS-CoV-1 SARS-CoV-2 sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 siRNA siRNAs subgenomic RNAs suppress target targeting the SARS-CoV-2 Treatment Vaccine development variant Viral viral infection viral infections viral replication virus virus replication viruses [DOI] 10.3390/v13102030 PMC 바로가기 [Article Type] Article