RCT – Page 17 – Communicable Diseases Research

Convalescent plasma for COVID-19: a meta-analysis, trial sequential analysis, and meta-regression

COVID-19에 대한 회복기 혈장: 메타 분석, 시험 순차 분석 및 메타 회귀

Meta-Analysis

Published on 2021-12-012022-09-11
Journal: British journal of anaesthesia [Category] 임상,

Developing a virtual assessment protocol for the AMPLIFI Randomized Controlled Trial due to COVID-19: From assessing participants’ preference to preparing the team

COVID-19로 인한 AMPLIFI Randomized Controlled Trial을 위한 가상 평가 프로토콜 개발: 참가자의 선호도 평가에서 팀 준비까지

Article

Published on 2021-12-012022-09-11
Journal: Contemporary clinical trials [Category] SARS, 임상,

Effect of azithromycin and hydroxychloroquine in patients hospitalized with COVID-19: Network meta-analysis of randomized controlled trials

COVID-19로 입원 한 환자에서 아지트로 마이신 및 하이드 록시 클로로 퀴인의 효과 : 무작위 대조 시험의 네트워크 메타 분석

Meta-Analysis

Published on 2021-12-012022-08-31
Journal: Journal of medical virology [Category] meta-analysis, 임상, 치료제,

[키워드] age all-cause mortality analyzed Azithromycin benefit calculated Chloroquine clinical outcomes Combination confidence interval coronavirus Coronavirus 2019 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection determine Effect effect size Efficacy Evidence HCQ heterogeneity hospitalized patient hospitalized patients Hydroxychloroquine inception Infection investigated mechanical ventilation Meta-analysis Mortality network Network meta-analysis network meta-analysis. no significant effect observational studies observational study Odds ratio outcome participant patients hospitalized Randomized controlled trial Randomized controlled trials ranged RCT RCTs reduce Research searched severity of COVID-19 significant effect Treatment with COVID-19
[DOI] 10.1002/jmv.27259 PMC 바로가기 [Article Type] Meta-Analysis

Use of novel antithrombotic agents for COVID-19: Systematic summary of ongoing randomized controlled trials

COVID-19에 대한 새로운 항혈전제의 사용: 진행중인 무작위 대조 시험의 체계적인 요약

Article

Published on 2021-12-012022-09-11
Journal: Journal of thrombosis and haemostasis : JTH [Category] SARS, 임상, 치료제,

[키워드] acting Activation affecting Anti-inflammatory Antithrombotic Antiviral antiviral effects benefit clinical coagulation cascade Coagulopathy Conventional coronavirus disease Coronavirus disease 2019 COVID-19 defibrotide drug Effect endothelial Endothelial cell fibrosis Health Organization help identify IMPROVE include Inflammatory response macro management mechanism nafamostat Oxygenation Patient Patient management patients with COVID-19 pleiotropic potential mechanism Randomized controlled trial Randomized controlled trials RCT RCTs reduce registry Result searched systematic literature search Trial triggered utility Viral load World Health Organization
[DOI] 10.1111/jth.15533 PMC 바로가기 [Article Type] Article

Randomized trial drug controlled compendious transcriptome analysis supporting broad and phase specific therapeutic potential of multiple candidates in COVID-19

Randomized Controlled Trial

Published on 2021-12-012022-10-04
Journal: Cytokine [Category] 바이오마커, 신약개발, 임상, 치료제,

[키워드] Admissions Affect Analysis Anticytokines antiinflammatory assumption benefit Biomarker candidate cellular clinical study coronavirus disease COVID-19 cytokine cytokine release Deceased Dexamethasone discharged disease Drug discovery drugs Effect effective Effectiveness examined expected hydroxychloroquine/chloroquine hyperinflammation ICU implicated inhibiting intensive care Intervention non-ICU opposite outcomes oxygen supplementation patients Predictive Proinflammatory cytokine proinflammatory cytokines randomized clinical trial RCT Regulation severity Stage supported the disease therapeutic effects therapeutic potential Therapeutics therapy Tofacitinib Transcriptome transcriptomic transcriptomic data Treatment Trial underlie Ventilation
[DOI] 10.1016/j.cyto.2021.155719 PMC 바로가기 [Article Type] Randomized Controlled Trial

The Scleroderma Patient-centered Intervention Network Self-Management (SPIN-SELF) Program: protocol for a two-arm parallel partially nested randomized controlled feasibility trial with progression to full-scale trial

경피증 환자 중심 중재 네트워크 자가 관리(SPIN-SELF) 프로그램: 전체 규모 시험으로 진행되는 2군 병렬 부분적으로 중첩된 무작위 통제 실행 가능성 시험을 위한 프로토콜

Study Protocol

Published on 2021-11-272022-09-10
Journal: Trials [Category] MERS, 임상,

[키워드] 1:1 Activation addition Anxiety Autoimmune charge chronic chronic disease Cohort connective tissue connective tissue disease criteria determine disease disseminate E-health Eligible participants evaluate the effect feasibility functional health IMPROVE include initial Intervention management managing media meeting moderate disease modifications network offer organization organizations outcome participant Patient Patient activation Primary outcome proceed Program progression protocol randomization Randomized Randomized controlled trial RCT recruited scale Scleroderma secondary Secondary outcomes Self-efficacy Self-management social media Spin stoppage supplementary material systemic Systemic sclerosis Trial Trial registration two-arm parallel usual care
[DOI] 10.1186/s13063-021-05827-z PMC 바로가기 [Article Type] Study Protocol

Comparing the clinical efficacy of COVID-19 vaccines: a systematic review and network meta-analysis

Covid-19 백신의 임상 효능 비교 : 체계적인 검토 및 네트워크 메타 분석

Meta-Analysis

Published on 2021-11-232022-08-31
Journal: Scientific Reports [Category] MERS, meta-analysis, SARS, 임상,

[키워드] Above acute respiratory syndrome Ad26.COV2.S assessment assessment tool Bia BNT162b2 Clinical efficacy clinical trial comparison controlled trials CoronaVac coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine database Efficacy eight Epidemiology evaluated Factor followed by Gam-COVID-Vac greater highest Intervention leading logistics mRNA mRNA-1273 mRNA-1273 vaccine mRNA-1273 vaccines Network meta-analysis New nine NMA no statistically significant difference pandemic participant Patient performed Phase 3 Prevent Primary outcome Primary outcomes Probability Randomized controlled trial RCT RCTs registration number respiratory risk risk of bia SARS-CoV-2 searched severe COVID-19 severe disease Side effects significantly statistically statistically significant difference symptomatic symptomatic COVID-19 symptomatic disease systematic review the vaccine the vaccines unique Vaccine Vaccines viral infection was tested while
[DOI] 10.1038/s41598-021-02321-z PMC 바로가기 [Article Type] Meta-Analysis

“Watch Me Grow- Electronic (WMG-E)” surveillance approach to identify and address child development, parental mental health, and psychosocial needs: study protocol

“아동 발달, 부모의 정신 건강 및 심리 사회적 요구를 식별하고 해결하기위한“성장하는 전자식 (WMG-E)”감시 접근법 : 연구 프로토콜

Study Protocol

Published on 2021-11-172022-09-10
Journal: BMC health services research [Category] MERS, SARS, 비임상, 임상,

[키워드] acceptability approach assessment breath Care Child development children closure CONSORT CONSORT statement continuity Continuity of care Controlled COVID-19 pandemic developmental Developmental surveillance Digital solution effective Electronic platform engage expand expected Families feasibility Health health organisation health organisations Health promotion health promotion program identify impacted implementation implication increased risk intervention group management mental health MONITOR Online health service pandemic parent Parent mental health parental parents platform Population Psychosocial needs Psychosocial stress Randomly RCT receive recommendation recommendations recruited Registered registration number resource resulting risk Screening Service navigation Study protocol Support Surveillance Trial Trial registration Version Virtual care
[DOI] 10.1186/s12913-021-07243-0 PMC 바로가기 [Article Type] Study Protocol

Thromboembolic and hemorrhagic risks after vaccination against SARS-CoV-2: a systematic review and meta-analysis of randomized controlled trials

Research

Published on 2021-11-132022-10-29
Journal: Thrombosis Journal [Category] COVID-19,

Telephone‐based behavioral activation with mental imagery for depression: A pilot randomized clinical trial in isolated older adults during the Covid‐19 pandemic

Randomized Controlled Trial

Published on 2021-11-102022-10-04
Journal: International Journal of Geriatric Psychiatry [Category] MERS, SARS, 임상,

[키워드] Activation activity scheduling Adults adverse effect alleviate assigned behavioral activation clinically control condition control group Depression depressive symptom Diagnostic Criteria Efficacy exacerbated feasibility feasible Government greater decrease help imagery increased risk increases in individual investigated Isolation Mental mental health problem mental imagery MOST objective Older Older adults open‐label pandemic participant pilot study psychological treatment randomized clinical trial Randomly RCT Result social distancing social isolation Symptom symptoms of depression Treatment treatment group vulnerable persons
[DOI] 10.1002/gps.5646 PMC 바로가기 [Article Type] Randomized Controlled Trial