Wide-awake local anaesthesia no tourniquet (WALANT) vs regional or general anaesthesia for flexor tendon repair in adults: protocol for a systematic review and meta-analysis성인의 굴곡건 수복을 위한 WALANT(광각성 국소마취 무지혈대) 대 국소 또는 전신 마취: 체계적인 검토 및 메타 분석을 위한 프로토콜Protocol Published on 2020-11-212022-08-31 Journal: Systematic Reviews [Category] Coronavirus, meta-analysis, SARS, [키워드] (epinephrine Abstract Adrenaline Aerosol generation anaesthesia Anaesthetics approach article best CINAHL clinical trial Cochrane Library comparator complications conducted conscious COVID-19 database determine epinephrine evaluate Evidence feasible Finger injuries Flexor tendon Flexor tendon injury flexor tendons functional general anaesthesia Grey Grey literature hand Hand injuries hand surgery healthcare professionals help IMPROVE include Injury intubation investigator knowledge language limitation Local Meta-analysis Methodological quality motion occur open operative time outcome outcome measures Patient peer review Penetrating penetrating injury Potential Primary outcome protocol random effect range of motion reduced reduced risk Referral Registered removal repair required resolved resource risk secondary Secondary outcomes spread to standard treatment Study protocol supplementary material surgeon surgery surgical systematic review Tendon injuries tourniquet undergo WALANT Wide-awake Wide-awake local anaesthesia no tourniquet wrist [DOI] 10.1186/s13643-020-01532-1 PMC 바로가기 [Article Type] Protocol
Clinical Characteristics and Risk Factors for Fatality and Severity in Patients with Coronavirus Disease in Korea: A Nationwide Population-Based Retrospective Study Using the Korean Health Insurance Review and Assessment Service (HIRA) DatabaseArticle Published on 2020-11-182022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Administered age Antibiotics assessment Cardiopulmonary Chronic kidney disease clinical Clinical characteristics Comorbidity confounding factors coronavirus COVID-19 COVID-19 patients COVID-19 severity database death defined develop Diabetes Mellitus disease severity drug effective Efficacy effort extracorporeal membrane oxygenation Factor fatality HIRA Hydroxychloroquine increased risk insurance interferon investigated Korean laboratory-confirmed male mechanical ventilator medication oseltamivir outcome Oxygen therapy pandemic Patient patients Pneumonia Prognosis reduced risk Retrospective study review ribavirin risk factor service severe COVID-19 severe disease severity shown significantly therapeutic Treatment [DOI] 10.3390/ijerph17228559 PMC 바로가기 [Article Type] Article
Antecedent Administration of Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Antagonists and Survival After Hospitalization for COVID-19 SyndromeObservational Study Published on 2020-11-172022-10-05 Journal: Journal of the American Heart Association [Category] 임상, [키워드] 95% CI ACE-2 ACEi acute respiratory syndrome administration affected age Analysis Angiotensin II angiotensin-converting enzyme inhibitor angiotensin-converting enzyme-2 angiotensin‐converting enzyme inhibitor angiotensin‐converting enzyme‐2 antagonist antecedent ARB cardiovascular risk congestive heart failure Coracle coronavirus coronavirus disease COVID-19 COVID‐19 death Diabetes Mellitus enzyme groups Hospitalization Hospitalized human cells hypertension in-hospital mortality inhibitor Italy Mortality Odds ratio Older overall mortality Patient patients patients hospitalized Primary outcome protective role receptor reduced reduced risk Region renin‐angiotensin converting enzyme inhibitor. Result SARS-CoV-2 SARS‐CoV‐2 Sex smoking status trend upregulation while with COVID-19 [DOI] 10.1161/JAHA.120.017364 PMC 바로가기 [Article Type] Observational Study
Relationship Between COVID-19 Infection and Risk Perception, Knowledge, Attitude, and Four Nonpharmaceutical Interventions During the Late Period of the COVID-19 Epidemic in China: Online Cross-Sectional Survey of 8158 AdultsOriginal Paper Published on 2020-11-132022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] 95% CI added adopted association Attitude categorical variable China Chinese conducted coughing COVID-19 COVID-19 infection COVID-19 outbreak Demographic variables determinant effective examined Fisher exact test increased risk Infection information Intervention knowledge Logistic regression logistic regression model majority Mask mask wearing nonpharmaceutical intervention nonpharmaceutical personal interventions NPI NPIs objective Odds ratio online survey Perception Period positive positive attitude predictor Protective public health reduced risk relationship Result risk Risk perception significantly social distancing survey were infected with COVID-19 [DOI] 10.2196/21372 PMC 바로가기 [Article Type] Original Paper
Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysisResearch Published on 2020-11-102022-11-01 Journal: Critical Care [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval acute respiratory distress age analyzed Antiviral treatment ARDS ARDS patient calculate caused CIs Clinical practice Cohort cohort study Comorbidities coronavirus disease Coronavirus disease 2019 Corticosteroid corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 COVID-19 patient Cox regression analysis Cox regression model dose enrolled hazard ratio Hospital admission HRs In-hospital death in-hospital mortality Invasive mechanical ventilation IQR low-dose corticosteroid median Methylprednisolone Mortality Organ failure outcome Patient patients with ARDS per day Primary outcome Propensity score propensity score analysis reduced risk reduction in Respiratory Support Result retrospective risk risk of death severe acute respiratory syndrome coronavirus 2 Sex single-center SOFA SOFA score standard treatment systemic corticosteroid therapy Treatment viral RNA clearance were used [DOI] 10.1186/s13054-020-03340-4 PMC 바로가기 [Article Type] Research
Risk of hospitalization for Covid-19 outpatients treated with various drug regimens in Brazil: Comparative analysisResearch article Published on 2020-11-012022-10-05 Journal: Travel medicine and infectious disease [Category] SARS, 치료제, [키워드] age antiviral medication approach benefit Brazil Cardiac arrhythmia Comparative analysis COVID-19 death disease drug regimen Efficacy emergency room ENhance EREmergency Room HCQ HCQhydroxychloroquine Health Maintenance Organization HMOHealth Maintenance Organization hospital Hospitalization Hydroxychloroquine magnitude medication medications mortality risk not significant obesity Older oseltamivir Outpatient pandemic patients physician Prednisone presenting protocol pulmonary inflammation reduce reduced reduced risk Result risk SARS-CoV-2-positive patient significantly Symptom treat treated Treatment type-2 diabete [DOI] 10.1016/j.tmaid.2020.101906 [Article Type] Research article
Patients with Inflammatory Bowel Disease Are Not at Increased Risk of COVID-19: A Large Multinational Cohort StudyArticle Published on 2020-10-312022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI age Cohort Containment measure Corticosteroid COVID-19 cumulative detrimental died drugs effective enrolled General population Hospitalization Hospitalized IBD Immunosuppression impacted incidence incidence of COVID-19 Increased increased risk increased the risk Inflammatory bowel disease intensive care unit investigated lethality lockdown monoclonal antibody multicenter multivariable analysis outcome Patient pharmacological Pneumonia preventing infection reduced risk risk risk of COVID-19 SARS-COV-2 infection Treatment [DOI] 10.3390/jcm9113533 PMC 바로가기 [Article Type] Article
Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million peopleSpecial Populations Published on 2020-10-312022-10-31 Journal: Heart (British Cardiac Society) [Category] COVID-19, MERS, SARS, [키워드] 95% CI ACE ACE inhibitor adjusted Admission African angiotensin receptor blocker ARB association black cardiac risk factors and prevention cohort study collected data confounders COVID-19 COVID-19 disease Cox proportional hazard diabetes diagnosed disease drug Effect England enzyme Epidemiology ethnic group finding geographical region group higher risk hypertension ICU ICU care increased risk inhibitor intensive care medication participant Patient primary care Primary outcome prospective cohort study raise receiving receptor reduced risk resulting risk risk of COVID-19 RT-PCR severe COVID-19 disease severity significant interaction significantly significantly increased sociodemographic factors susceptibility variables with COVID-19 [DOI] 10.1136/heartjnl-2020-317393 PMC 바로가기 [Article Type] Special Populations
Thromboprophylaxis with enoxaparin is associated with a lower death rate in patients hospitalized with SARS-CoV-2 infection. A cohort studyResearch paper Published on 2020-10-052022-10-31 Journal: EClinicalMedicine [Category] COVID-19, [키워드] Adjusted analysis Admission analyzed caused Cohort cohort study collected coronavirus Coronavirus disease 2019 COVID-19 death rate Effect Endothelial cell enoxaparin evaluated Evidence finding foundation heparin hospital Hospital stay Hospitalization hypercoagulability in-hospital mortality Infection intensive care intensive care unit Invasion Logistic regression low molecular weight heparin Mortality multivariate nine overlap weight Patient patients hospitalized patients treated Poisson regression polymerase chain positive Proinflammatory cytokine randomized clinical trial Rate Ratio real time reduce reduced risk respiratory reverse transcription risk RT-PCR SARS-CoV-2 SARS-COV-2 infection Secondary outcomes Support Thromboprophylaxis Treatment was used [DOI] 10.1016/j.eclinm.2020.100562 PMC 바로가기 [Article Type] Research paper
Efficacy of tocilizumab in patients with COVID-19 ARDS undergoing noninvasive ventilationResearch Published on 2020-09-292022-11-01 Journal: Critical Care [Category] COVID-19, SARS, [키워드] 95%CI acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome adjusted Admission age ARDS ARF association asymptomatic patient case-control study Comorbidity consecutive patient Controlled trial coronavirus coronavirus disease COVID-19 COVID-19 patient CRP develop died effective effective therapy Efficacy and safety elevated Evidence Follow-up IL-6 levels in-hospital mortality rate Infection intravenous Intubated Kaplan-Meier method lung lesion mechanical ventilation Multivariate analysis NIV noninvasive Noninvasive ventilation outcome overall mortality Patient patients patients with COVID-19 Primary outcome Probability progression Pulmonology receiving reduced risk required Respiratory failure respiratory impairment Result retrospective SARS-CoV-2 severe COVID-19 Severe COVID-19 pneumonia severity significantly lower syndrome TCZ the patient Tocilizumab total patient treated Treatment Two patient unit worsening [DOI] 10.1186/s13054-020-03306-6 PMC 바로가기 [Article Type] Research