Plasmodium vivax malaria complicated by splenic infarctarticle Published on 2014-02-282024-09-01 Journal: Paediatrics and International Child Health [Category] 말라리아, [키워드] Infarct Malaria, Plasmodium vivax spleen [Article Type] article
Transcriptional analysis of the innate immune response of ducks to different species-of-origin low pathogenic H7 avian influenza virusesResearch Published on 2013-03-232023-05-31 Journal: Virology Journal [Category] Fulltext, [키워드] Avian Influenza Avian innate immunity microarray (AIIM) duck Innate immunity Low pathogenicity Pathogenesis qRT-PCR spleen Transcriptome [DOI] 10.1186/1743-422X-10-94 PMC 바로가기 [Article Type] Research
Programmed Death (PD)-1-Deficient Mice Are Extremely Sensitive to Murine Hepatitis Virus Strain-3 (MHV-3) InfectionResearch Article Published on 2011-07-072022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] activate anti-IFN-γ anti-TNF-α Author blockade cascades CD4 CD8 cells characteristic co-expressed Coagulation Combination Control damaged demonstrated described determined exhibited expression Fgl2 FH fibrinogen Fluorescence fulminant viral hepatitis functional hepatocellular IFN-γ immunopathological immunopathological damage Immunotherapy in vivo Infection inhibitory receptor initiate injection investigated led to limit liver Liver damage Lymph node lymph nodes mAb Macrophage maintain mechanism mice Mortality mortality rate mRNA multiple organs murine hepatitis virus Necrosis NK cell occurred organ Pathogenesis peripheral tolerance produced promote Protein Quantitative reduced related RT-PCR sensitive Signaling significantly higher spleen T cells tissue tissue damage tissue lesion tissue lesions TNF-α Transcription was determined wild type wild-type [DOI] 10.1371/journal.ppat.1001347 PMC 바로가기 [Article Type] Research Article
SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent MechanismResearch Article Published on 2010-04-082022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] acute lung injury acute respiratory syndrome affecting alveolar inflammation ARDS Author BALB/c mice caused cell proliferation clinical disease coronavirus death demonstrated Dependent died Diffuse alveolar damage ENhance Epidemic evaluated highly pathogenic I, II independent Infected Infection innate immune innate immune response Innate immunity interferon interferon signaling knockout mice lack liver Lung disease Lung injury Lung pathology MA15 mechanism mice molecular mechanism Mortality Mouse models other tissue outcomes Pathogenesis Pathways Post-infection PROTECT Protein pulmonary fibrosis pulmonary lesion question receptor regulated respiratory respiratory virus SARS Coronavirus SARS pathogenesis SARS-CoV SARS-CoV infection severe severe disease Signaling spleen Stat1 the epidemic Type type I type III interferon viral pathogenesis virus virus pathogenesis virus titer Virus-host interaction viruses weight loss wildtype [DOI] 10.1371/journal.ppat.1000849 PMC 바로가기 [Article Type] Research Article
Immunohistochemistry for detection of avian infectious bronchitis virus strain M41 in the proventriculus and nervous system of experimentally infected chicken embryosResearch Published on 2009-02-052022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] addition Affect age Allantoic fluid Antigen Brain bronchitis Cell chorioallantoic collected detected Diagnosis diagnostic different disease Embryo embryonic embryos fixed found gastrointestinal tract generate IBV IBV infection IHC immunohistochemistry induce Infected Infection Infectious Bronchitis Virus inoculated kidney kidneys liver lung M41 membrane MOST Myocardial nasal epithelium nervous system Neuron oviduct Pathogenesis PI Respiratory system Result sensitivity spleen strain Strains tissue tissue tropism vasculature virulence virus virus isolation [DOI] 10.1186/1743-422X-6-15 PMC 바로가기 [Article Type] Research
Studies on the Tissue-Related Phenotypic Heterogeneity of Murine B CellsResearch Article Published on 1998-01-012023-08-30 Journal: Developmental Immunology [Category] E형 간염, [키워드] B cells Bone marrow IBL-2 L-selectin SCID spleen [DOI] 10.1155/1998/61492 PMC 바로가기 [Article Type] Research Article