Trigger factor assisted soluble expression of recombinant spike protein of porcine epidemic diarrhea virus in Escherichia coliResearch Article Published on 2016-05-042022-10-27 Journal: BMC Biotechnology [Category] Coronavirus, [키워드] antigens chaperone Chaperone co-expression system cloned co-expression condition contagious develop elicited ELISA epidemic diarrhea Escherichia coli expressed expression expression vectors immune immunization immunogenic Inclusion inclusion bodies mAb mice neutralizing antibody pathogen PEDV produced Protein protein antigen Proteins purified reactivity Recombinant protein recombinant proteins Recombinant spike protein Result S protein sera serum IgG Serum neutralizing antibody spike glycoprotein Strains subunit Subunit vaccine supplementary material tested Trigger Trigger factor Vaccine variety virus western blot [DOI] 10.1186/s12896-016-0268-7 PMC 바로가기 [Article Type] Research Article
S1 domain of the porcine epidemic diarrhea virus spike protein as a vaccine antigenResearch Published on 2016-04-012022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] affinity age analysed binding Cell cellular receptor clinical parameter colostrum Complete contagious diarrhea disease effective ELISA epidemic diarrhea Epitopes eukaryotic exhibited expressed expression highest identify IgA IgG immune response immunization immunized improvement infecting Infection intramuscularly Lactogenic immunity less mammalian mammalian cell morbidity and mortality Mortality N-terminal neutralizing antibody Newborn no significant difference PEDV pregnant produced PROTECT Protein Recombinant S1 protein responsible Result S1 S1 domain S1 protein S1 subunit SDS-PAGE sera serum significantly lower Spike protein subunit Subunit vaccine tested titre transferred vaccination Vaccine vaccine antigen virus Virus neutralization virus neutralization assays virus spike protein yeast [DOI] 10.1186/s12985-016-0512-8 PMC 바로가기 [Article Type] Research
Effectiveness of subunit influenza vaccination in the 2014-2015 season and residual effect of split vaccination in previous seasonsArticle Published on 2016-03-082023-06-24 Journal: Vaccine [Category] 신종인플루엔자, [키워드] Influenza influenza vaccine Split-virion vaccine Subunit vaccine vaccine effectiveness [DOI] 10.1016/j.vaccine.2016.01.054
Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirusResearch Article Published on 2016-03-022023-06-14 Journal: Cellular and Molecular Immunology [Category] Fulltext, MERS, [키워드] adjuvant effects MERS MERS-CoV Receptor-binding domain Subunit vaccine [DOI] 10.1038/cmi.2015.03 PMC 바로가기 [Article Type] Research Article
Long-term immunogenicity and safety of an investigational herpes zoster subunit vaccine in older adults노인에서의 연구용 대상 포진 서브유닛 백신의 장기 면역원성과 안전성Clinical Trial Published on 2016-02-032023-06-02 Journal: Vaccine [Category] 대상포진, 두창, [키워드] glycoprotein E immunogenicity NCT01295320 persistence Subunit vaccine Varicella-Zoster Virus [DOI] 10.1016/j.vaccine.2015.09.073 [Article Type] Clinical Trial
A novel plant-produced Pfs25 fusion subunit vaccine induces long-lasting transmission blocking antibody responsesarticle Published on 2015-12-312024-09-01 Journal: Human vaccines & immunotherapeutics [Category] 말라리아, [키워드] fusion protein lichenase malaria Pfs25 plant-produced antigen Plasmodium falciparum Subunit vaccine Transmission blocking vaccine [Article Type] article
Immunogenicity of porcine P[6], P[7]-specific △VP8* rotavirus subunit vaccines with a tetanus toxoid universal T cell epitope파상풍 톡소이드 보편적 T 세포 에피토프를 갖는 돼지 P[6], P[7] 특이 △VP8* 로타바이러스 서브유닛 백신의 면역원성journal-article Published on 2015-08-012024-07-30 Journal: Vaccine [Category] 파상풍, [키워드] P type Porcine rotavirus Subunit vaccine T cell epitope tetanus toxoid VP8* protein. [DOI] 10.1016/j.vaccine.2015.07.011 [Article Type] journal-article
Immunogenicity of H1N1 influenza virus-like particles produced in Nicotiana benthamianaArticle Published on 2015-01-012023-06-25 Journal: Human vaccines & immunotherapeutics [Category] 신종인플루엔자, [키워드] hemagglutinin Influenza plant-based production Subunit vaccine transient expression Virus-like particle [DOI] 10.4161/hv.34365 PMC 바로가기
Receptor-binding domain-based subunit vaccines against MERS-CoVArticle Published on 2014-11-202022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] animal model assist caused coronavirus develop development domain effective Effective vaccines Human MERS MERS coronavirus MERS-CoV MERS-CoV vaccines Middle East Middle East respiratory syndrome Coronavirus Pandemics Protein provide RBD Receptor-binding domain researcher Safe Spread Subunit vaccine subunit vaccines syndrome Vaccine development Vaccines [DOI] 10.1016/j.virusres.2014.11.013 PMC 바로가기 [Article Type] Article
A glycoprotein subunit vaccine elicits a strong Rift Valley fever virus neutralizing antibody response in sheepArticle Published on 2014-10-012023-06-02 Journal: Vector Borne and Zoonotic Diseases [Category] 조류인플루엔자, [키워드] Glycoproteins Neutralizing antibodies Rift Valley fever virus sheep Subunit vaccine [DOI] 10.1089/vbz.2014.1650 PMC 바로가기