Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 ExpressionImmunology Published on 2018-12-132022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, [키워드] abrogated accompanied administration allergic rhinitis ALT anti-inflammatory property Apoptosis AST Asthma CC10 Cell cells co-immunoprecipitation control group determine disease downregulated Effect examined expression Fgl2 fulminant fulminant hepatitis HBP1 Hepatitis histology Human IL-1β Immune cell in vitro Infection inhibit inhibitory effect injection innate immune responses Interaction investigated involved kDa Kupffer cells liver Liver damage Liver function Macrophage macrophages mechanism MHV-3 mice murine hepatitis virus Necrosis pathogenic peritoneal macrophage PROTECT Protein Real-time PCR Regulation Regulatory represse serum shown significantly strain suggested survival rate THP-1 TNF-α transcription factor Treatment Vein viral infection was reduced western blot [DOI] 10.3389/fimmu.2018.02935 PMC 바로가기 [Article Type] Immunology
The In Ovo Delivery of CpG Oligonucleotides Protects against Infectious Bronchitis with the Recruitment of Immune Cells into the Respiratory Tract of ChickensCommunication Published on 2018-11-152022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] activating avian macrophage Bacterial CD4+ CD4+ cell CD8α+ cell chicken Cluster CpG CpG oligonucleotide days post infection delivery determine embryonic IBV IBV infection immune response In ovo Infectious Bronchitis Virus interferon lung macrophages mechanism morbidity and mortality mRNA oligonucleotide PROTECT protective effect recruitment reduce reduced respiratory respiratory tract shown signaling pathway significantly higher survival rate T lymphocytes Toll-like receptor tract viral infections [DOI] 10.3390/v10110635 PMC 바로가기 [Article Type] Communication
Analysis of prognostic factors of more/equal to10 years of survival for liver cancer patients after liver transplantationArticle Published on 2018-09-262023-06-03 Journal: Journal of cancer research and clinical oncology [Category] B형 간염, [키워드] carcinoma hepatocellular Liver transplantation Prognosis Risk factors survival rate [DOI] 10.1007/s00432-018-2756-8 PMC 바로가기
Efficacy of genogroup 1 based porcine epidemic diarrhea live vaccine against genogroup 2 field strain in JapanResearch Published on 2018-02-022022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] Administered Antibody titer caused Clinical sign conditions control group diarrhea Efficacy epidemic diarrhea evaluated exhibited immune response Immunity Infectious disease Japan lactogenic Lactogenic immunity mortality rate negative control Newborn PEDV Porcine epidemic diarrhea Porcine epidemic diarrhea virus pregnant prevalent reduced Result serum significantly supplementary material survival rate Symptom the vaccine vaccination Vaccine virus Virus neutralization watery [DOI] 10.1186/s12985-018-0940-8 PMC 바로가기 [Article Type] Research
Effective inhibition of MERS-CoV infection by resveratrolResearch Article Published on 2017-02-132022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, [키워드] addition administration analyzed Antiviral antiviral activity antiviral medicine antiviral property Apoptosis approved can be used cause cellular Concentration coronavirus demonstrated down-regulated Effectiveness expression in vitro inhibited inhibition inhibitory MERS-CoV MERS-CoV infection MERS-CoV virus infection MERS-CoV-infected patients Middle East Middle East Respiratory Syndrome Virus morbidity and mortality MTT neutral red nucleocapsid performed Plaque assay Protein protein expression quantitative PCR reduce Replication respiratory Result resveratrol significantly survival survival rate treat Treatment Vaccine VERO E6 cells viral pathogen Viral RNA virus infection [DOI] 10.1186/s12879-017-2253-8 PMC 바로가기 [Article Type] Research Article
Efficacy of delayed treatment of China-made Peramivir with repeated intravenous injections in a mouse influenza model: from clinical experience to basal experimentResearch Article Published on 2016-07-082023-05-25 Journal: BMC Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] delayed treatment Lung index Lung virus titer Peramivir survival rate [DOI] 10.1186/s12879-016-1589-9 PMC 바로가기 [Article Type] Research Article