Antibody responses – Page 18 – Communicable Diseases Research

Humoral Immunity against SARS-CoV-2 and the Impact on COVID-19 Pathogenesis

SARS-CoV-2에 대한 체액 면역 및 COVID-19 발병에 미치는 영향

Review

Published on 2021-06-302022-09-11
Journal: Molecules and cells [Category] MERS, SARS, 변종, 진단,

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection

mRNA-1273 백신 접종에 의해 유도된 항체는 SARS-CoV-2 감염에서보다 수용체 결합 도메인에 더 광범위하게 결합합니다

Research Article

Published on 2021-06-302022-09-10
Journal: Science Translational Medicine [Category] MERS, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive Adaptive immunity affected antibodies antibody antibody epitope antibody epitopes antibody immunity Antibody Response Antibody responses antigenic evolution binding breadth characterized convalescent sera coronavirus deep demonstrated dose elicited epitope Epitopes erosion greater human antibody response Immunity immunization Infection less Moderna mRNA-1273 vaccine mRNA mRNA-1273 mRNA-1273 COVID-19 vaccine Mutation natural infection neutralization Neutralizing activity Neutralizing antibodies neutralizing antibody polyclonal antibodies polyclonal antibody raised RBD RBD mutation RBD-binding antibody Receptor binding domain Receptor-binding domain respiratory SARS-CoV-2 SARS-CoV-2 evolution SARS-COV-2 infection SARS-CoV-2 spike protein sera severe acute respiratory syndrome Coronavirus specificity Spike protein susceptibility the antibody response the RBD the receptor-binding domain the SARS-CoV-2 vaccination Vaccine variant variants Viral viral evolution viral mutation Viral mutations
[DOI] 10.1126/scitranslmed.abi9915 PMC 바로가기 [Article Type] Research Article

Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19

Covid-19 후 최대 12.5 개월까지 의료 종사자의 혈청 양성 및 재감염의 지속성 및 기준 결정 요인

Correspondence

Published on 2021-06-282022-09-01
Journal: BMC Medicine [Category] MERS, SARS, 진단, 치료기술,

[키워드] allergies Anosmia anosmia/hypogeusia antibodies antibody antibody level antibody levels Antibody Response Antibody responses Antigen baseline Baseline determinants Care Cohort correlated COVID-19 COVID-19 symptom COVID-19 symptoms COVID-19 vaccine determinant domain Duration Fever first episode Health Health care Health care worker health care workers Hope Hospitalization Hypogeusia IgA IgG IgG response IgG responses IgM Immunity individual Kinetics long-lasting Occurrence Patient Primary Health Care prospective cohort raise Reinfection SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike antigen seronegative Seropositivity significantly smoking Spanish Spike antigen STABLE subset supplementary material symptoms onset
[DOI] 10.1186/s12916-021-02032-2 PMC 바로가기 [Article Type] Correspondence

Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19

급성 COVID-19 환자에서 설사, 대변 바이러스 RNA 및 SARS-COV-2- 특이 적 IGA에도 불구하고 제한된 장 염증

Article

Published on 2021-06-252022-09-01
Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 변종, 진단, 치료기술, 치료제,

[키워드] acute COVID-19 Antibody Response Antibody responses characterized Cohort controls COVID-19 disease COVID-19 patient COVID-19 patients Cytokines detected in stool diarrhea died difficulty Evidence evidence of fecal Gastrointestinal gastrointestinal symptoms gastrointestinal tract Gut hospitalized COVID-19 patients IgA IgA response IL-10 IL-23 IL-8 immune response individual infected individuals Infection Inflammation inflammatory markers intestinal Intestinal diseases intestinal inflammation Limited microbiome composition Mucosal immunology nasopharynx Patient SARS-CoV-2 SARS-CoV-2 RNA severe COVID-19 disease severe disease specimen Stool stool samples strain Strains survived Symptom tissue samples Translational research uninfected Viral Viral RNA
[DOI] 10.1038/s41598-021-92740-9 PMC 바로가기 [Article Type] Article

Clinical Evaluation of the Abbott Alinity SARS-CoV-2 Spike-Specific Quantitative IgG and IgM Assays among Infected, Recovered, and Vaccinated Groups

Abbott Alinity SARS-CoV-2 스파이크 특이적 정량적 IgG 및 IgM 분석의 감염, 회복 및 백신 접종 그룹의 임상 평가

Article

Published on 2021-06-182022-09-11
Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단, 치료법,

[키워드] Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody Response Antibody responses Antibody test booster clinical clinical sensitivity Cohort collected Combination Containment coronavirus coronavirus disease Coronavirus infections COVID-19 COVID-19 vaccines cross-reactivity dampened response dose group Health IgG IgG and IgM IgM immune responses Immunity immunoassays individual individuals Infection Laboratory nucleocapsid pandemic participant Quantitative recovered respiratory response SARS-CoV-2 sensitivity serologic assay Serological assay serological response serology assay serology assays severe acute respiratory syndrome Coronavirus significant increase spike Spike protein unique utility vaccination Vaccine while
[DOI] 10.1128/JCM.00388-21 PMC 바로가기 [Article Type] Article

Declining Levels of Neutralizing Antibodies Against SARS-CoV-2 in Convalescent COVID-19 Patients One Year Post Symptom Onset

증상 발병 1년 후 회복기 COVID-19 환자에서 SARS-CoV-2에 대한 중화 항체 수준 감소

Immunology

Published on 2021-06-162022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법,

[키워드] Against antibody Antibody Response Antibody responses B.1.351 collected concerning convalescent patient Convalescent patients coronavirus disease Coronavirus disease 2019 COVID-19 declining detectable donors E484K fraction Humoral immunity IgG antibodies IgG titers IgM and IgG immune responses individual Infection Kinetics knowledge Level long-term immune response long-term immune responses Major natural infection neutralization test neutralization tests neutralize Neutralizing Neutralizing activity nucleocapsid Onset Patient patients performed PROTECT Protein quantified RBD Receptor binding domain recognizing recovered patient recovered patients SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific IgG South Africa specific IgG antibodies spike Spike protein symptom onset symptomatic symptomatic COVID-19 the spike protein vaccination Vaccinations variant virus VoC Year
[DOI] 10.3389/fimmu.2021.708523 PMC 바로가기 [Article Type] Immunology

Serological profiles of pan-coronavirus-specific responses in COVID-19 patients using a multiplexed electro-chemiluminescence-based testing platform

다중 전기 화학 발광 기반 테스트 플랫폼을 사용한 COVID-19 환자에서 Pan-Coronavirus 특이 적 반응의 혈청 학적 프로파일

Research Article

Published on 2021-06-032022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 치료법,

[키워드] antibody Antibody Response antibody response against Antibody responses carried collected Contact tracing COVID-19 COVID-19 patient COVID-19 sample COVID-19 samples CoVs cross-reactive cross-reactivity diagnosed with COVID-19 Diagnosis diagnostic domain epitope epitope specificity full-length spike protein group healthcare HKU1 hospital human coronavirus human CoV human CoVs IgG response IgG responses IgM and IgG IgM response IgM responses MERS MERS-CoV Multiplex assay N-terminal domain Non-COVID-19 nucleocapsid protein OC43 occur plasma sample plasma samples platform Prevalence profile Protein reactivity Receptor-binding domain reported response responses robust SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 nucleocapsid SARS-CoV-2 spike protein seasonal coronavirus serological assessment South South Korea specificity Spike protein Spike proteins subject Symptom the SARS-CoV-2 the spike protein unique
[DOI] 10.1371/journal.pone.0252628 PMC 바로가기 [Article Type] Research Article

COVID-19: Seroprevalence and Vaccine Responses in UK Dental Care Professionals

COVID-19: 영국 치과 진료 전문가의 혈청 유병률 및 백신 반응

Research Reports

Published on 2021-06-022022-09-10
Journal: Journal of Dental Research [Category] MERS, SARS, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis anti–SARS-CoV-2 IgG antibodies antibody Antibody Response Antibody responses baseline Care Cohort coronavirus coronavirus disease Coronavirus disease 2019 DCPs dental dentistry Deprivation detectable enzyme-linked immunosorbent enzyme-linked immunosorbent assay estimate exposure to First wave Follow-up future infection greater Guidance health guidance Health Organization Immunological memory individual Infection Infection prevention infection with SARS-CoV-2 initial International international standard leads magnitude natural natural infection occupational exposure occurred pandemic participant Personal protective equipment Pfizer-BioNTech polymerase chain polymerase chain reaction PPE professional public health recruited reduced risk respiratory response retained risk robust SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 spike glycoprotein second wave seroepidemiological studies serological response seropositive Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus significantly higher single dose spike glycoprotein Support thought United Kingdom vaccination Vaccine was determined West World Health Organization
[DOI] 10.1177/00220345211020270 PMC 바로가기 [Article Type] Research Reports

Antibody evasion by the P.1 strain of SARS-CoV-2

SARS-CoV-2의 P.1 균주에 의한 항체 회피

Article

Published on 2021-05-272022-09-11
Journal: Cell [Category] Fulltext, SARS, 변종, 진단,

[키워드] Abstract ACE2 ACE2 binding site ACE2-binding site Analysis antibodies antibody Antibody responses B.1.1.7 B.1.351 Brazil change changes in chimeric chimeric antibodies current E484K elicit escape explain functional isolates K417N less light chain mAb monoclonal antibody multiple mutations Mutation mutations N501Y natural infection neutralization neutralization potency neutralize Neutralizing antibody response neutralizing antibody responses new strain P.1 P.1 variant pandemic RBD RBD mutations Receptor-binding domain restored reveal SARS-CoV-2 SARS-CoV-2 pandemic significantly South Africa spike Structural analysis Structure the receptor-binding domain the SARS-CoV-2 vaccination Vaccine vaccine-induced antibody response variant VH3-53 Virus spike
[DOI] 10.1016/j.cell.2021.03.055 PMC 바로가기 [Article Type] Article

Outcomes of patients with end stage kidney disease on dialysis with COVID-19 in Abu Dhabi, United Arab Emirates; from PCR to antibody

아랍에미리트 아부다비에서 코로나19 투석을 받은 말기 신장질환 환자의 결과; PCR에서 항체로

Research

Published on 2021-05-262022-09-01
Journal: BMC Nephrology [Category] SARS, 진단, 치료제,

[키워드] Abu addition age antibody Antibody Response Antibody responses Asymptomatic average average age camostat characteristics of patient Cohort combinations Community Comorbidities concerning Contact contributed cough country COVID 19 COVID-19 COVID-19 infection COVID19 Critical care defined demographics develop diabete diabetes dialysis disease drug End stage kidney disease examined family Favipiravir Haemodialysis heart disease Hydroxychloroquine hypertension ICU IgG antibody individual infected individual infected individuals Infection Ischaemic heart disease Isolation Kidney disease lack Local Lopinavir lower mortality majority male median time Mild Mild disease Mortality Most patients negative PCR test outcome overall mortality Patient patients PCR PCR positive patient PCR positivity PCR tests performed Population positive patient positive patients presenting symptoms Rapid required Result Ritonavir Screening screening strategy serology source of infection spread of COVID-19 steroid Steroids study period subset symptomatic tested the antibody response Tocilizumab Viral viral clearance was performed were used with COVID-19
[DOI] 10.1186/s12882-021-02378-y PMC 바로가기 [Article Type] Research