Improved sensitivity, safety, and rapidity of COVID-19 tests by replacing viral storage solution with lysis bufferResearch Article Published on 2021-03-302022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] clinical sample collected Conducting COVID-19 pandemic COVID-19 patient COVID-19 test COVID-19 tests did not reduce Efficiency equipment healthy controls IMPROVE Improved lysis buffer MONITOR nasopharyngeal swabs not affect nucleic acid Patient PCR cycle PCR test replacing RNA RNA extraction RT-qPCR test SARS-CoV-2 SARS-CoV-2 detection sensitivity significantly more Swab temperature tested threshold virus VTM [DOI] 10.1371/journal.pone.0249149 PMC 바로가기 [Article Type] Research Article
Hepatic Steatosis, Rather Than Underlying Obesity, Increases the Risk of Infection and Hospitalization for COVID-19Medicine Published on 2021-03-292022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Affect age Analysis baseline Biomarker BMI body mass index Cohort cohort study COVID-19 COVID-19 test described determine disease disease severity fat Fatty liver fraction Gender healthy hepatic hepatic steatosis Hospitalization Hospitalized increase increased risk individual individuals Infection liver liver fat measure MRI multivariate logistic regression obese obesity participant performed Personalized medicine phenotypic positive positive test result Prospective PROTECT public policy risk factor risk of infection secondary severity tested UK biobank UK Biobank data variable was determined with COVID-19 [DOI] 10.3389/fmed.2021.636637 PMC 바로가기 [Article Type] Medicine
Sociodemographic characteristics and risk factors related to SARS-CoV-2 infection in Luanda, AngolaResearch Article Published on 2021-03-252022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Angola Characteristics Chi-square COVID-19 test effort Frequency Gender greater Healthcare professional identify individual Infection infection rate Logistic regression positive risk risk factor risk of infection SARS-CoV-2 SARS-COV-2 infection screened Sociodemographic characteristics Symptoms tested were used women [DOI] 10.1371/journal.pone.0249249 PMC 바로가기 [Article Type] Research Article
Identifying optimal COVID-19 testing strategies for schools and businesses: Balancing testing frequency, individual test technology, and cost학교 및 기업을 위한 최적의 COVID-19 테스트 전략 식별: 테스트 빈도, 개별 테스트 기술 및 비용 균형 조정Research Article Published on 2021-03-252022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] anticipated approach balancing base Characteristics Combination Community compartmental model COVID-19 test COVID-19 testing cumulative data set Disease prevalence effective Efficiency examined False positives finding Frequency identify identifying include Increasing Infection infections moderate outcome per day pooling positive Prevalence provided reduce reduction reductions in Sample School Schools sensitivity Sensitivity and specificity Sensitivity test Surveillance susceptible Symptom the disease underlying disease variable while [DOI] 10.1371/journal.pone.0248783 PMC 바로가기 [Article Type] Research Article
Socioeconomic Inequalities and Ethnicity Are Associated with a Positive COVID-19 Test among Cancer Patients in the UK Biobank CohortArticle Published on 2021-03-252022-10-31 Journal: Cancers [Category] COVID-19, [키워드] 95%CI added Cancer cancer patient Cancer patients case-control study Cohort conducted Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 disease COVID-19 incidence COVID-19 infection COVID-19 test COVID-19 transmission diagnosed Epidemiology Ethnicity Evidence finding First wave FIVE group Haematological cancer higher risk highlight identify improvement increased risk independent risk factor index inequality Infection information knowledge less malignancy obesity Other outcome pandemic Pandemics participant positive risk risk factor Risk factors severity simple smoking socio-demographic Socioeconomic factor Stratification Test tested Treatment UK biobank vaccination [DOI] 10.3390/cancers13071514 PMC 바로가기 [Article Type] Article
Association of Vitamin D Levels, Race/Ethnicity, and Clinical Characteristics With COVID-19 Test Results코로나19 검사 결과와 비타민 D 수치, 인종/민족, 임상적 특성의 연관성Research Published on 2021-03-192022-09-12 Journal: JAMA Network Open [Category] SARS, 진단, [키워드] 25-hydroxyvitamin D 95% CI Affect age Analysis analyzed Asian association black calcifediol Chain Reaction change Characteristics Chicago clinical clinical trial clinical trials cohort study Comorbidity conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 test COVID-19 testing Deficient defined demographic characteristics determine dose exposure finding greater Importance incidence rate increase in individual individuals less Lower measure multivariable analyses Multivariate analysis objective outcome participant Point polymerase chain polymerase chain reaction Polymerase chain reaction testing positive positive COVID-19 positive result positive test result randomized clinical trial randomized clinical trials rate ratio Relevance Result retrospective cohort study risk setting significantly single-center statistically significant Test test result tested Treatment Vitamin D vitamin D level vitamin D levels was measured was used white with COVID-19 women [DOI] 10.1001/jamanetworkopen.2021.4117 PMC 바로가기 [Article Type] Research
Impact of the 1st and 2nd Wave of the COVID-19 Pandemic on Primary or Revision Total Hip and Knee Arthroplasty—A Cross-Sectional Single Center StudyArticle Published on 2021-03-182022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age analyzed Arthroplasty center change COVID-19 COVID-19 pandemic COVID-19 test COVID-19 testing cross-sectional decrease evaluate evaluated First wave Gender hip hip and knee arthroplasty Impact incline joint knee lockdown pandemic impact performed preoperative reduction reduction in revision second wave single-center study Society Total was performed Wave [DOI] 10.3390/jcm10061260 PMC 바로가기 [Article Type] Article
Nasopharyngeal Swab for COVID-19 Test Necessitating Mechanical Ventilation and TracheostomyInfectious Disease Published on 2021-03-152022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome airway Anatomy anticoagulation Atrial fibrillation bleeding Case report CDC center co-morbidity Control coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 test dead Epistaxis extubation higher risk hypoxemic hypoxia intubation invasive male Mechanical mechanical ventilation nasal nasal swab nasopharyngeal nasopharyngeal swabbing nine NP swab nursing home Obtaining oral anticoagulant Patient PCR testing polymerase chain Population prevention Probability raise rehabilitation reported risk Saliva salivary SARS- CoV-2 SARS-CoV-2 suggested Support swabbing Test tracheostomy transcriptase transferred ventilator virus particle was obtained was performed WHO World Health Organization [DOI] 10.7759/cureus.13908 PMC 바로가기 [Article Type] Infectious Disease
Olfactory Dysfunction in Frontline Health Care Professionals During COVID-19 Pandemic in BrazilPhysiology Published on 2021-03-092022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] acute respiratory syndrome analyzed Anosmia Brazil Care Characteristics clinics Comorbidities concerning coronavirus coronavirus disease correlated COVID-19 COVID-19 test cross-sectional decrease diagnosed with COVID-19 dysfunction General population Health Health care Health care worker Hyposmia incidence Infection Inflammatory information intensive care unit intensive care units investigated nasal Olfaction disorders olfactory olfactory dysfunction olfactory function pandemic participant patients positive Prevalence professional professionals questionnaire researcher respiratory tract infection respiratory viral infection respiratory virus responses SARS-CoV-2 sense of smell significantly Smell loss subject Symptom Symptoms Taste tested the disease triggered upper virus with COVID-19 [DOI] 10.3389/fphys.2021.622987 PMC 바로가기 [Article Type] Physiology
Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK BiobankOriginal Article Published on 2021-03-082022-10-28 Journal: Aging Clinical and Experimental Research [Category] COVID-19, MERS, SARS, [키워드] acute COVID-19 adjusted Admission Adverse Affect age alterations Arterial stiffness association baseline body mass index Cardiovascular Magnetic Resonance cardiovascular risk factors Care cholesterol classical coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 test COVID-19 testing Critical care death Deprivation diabetes died Fractions greater hospital hypertension independent indolent likelihood male multivariable logistic regression Myocardial infarction observational study Older participant phenotype Phenotypes positive Public Health England required Result severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Sex significantly higher smoking stroke supplementary material tested UK biobank ventricular Volume with COVID-19 [DOI] 10.1007/s40520-021-01808-z PMC 바로가기 [Article Type] Original Article