Therapeutic Use of Dendritic Cells to Promote the Extranodal Priming of Anti-Tumor ImmunityArticle Published on 2013-11-032023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] Cancer cross-priming dendritic cells extranodal therapy [DOI] 10.3389/fimmu.2013.00388 PMC 바로가기
Regulation of macrophage and dendritic cell function by pathogens and through immunomodulation in the avian mucosaReview Published on 2013-11-012023-06-02 Journal: Developmental and comparative immunology [Category] 조류인플루엔자, [키워드] (Draining) lymph nodes Ag AIV Antigen antigen-presenting cells APC Avian influenza virus BALT BM Bone marrow bronchus-associated lymphoid tissue C-type lectin receptors CG chicken galectin chicken lung lectin CLL CLR DC DC-SIGN DC-specific intercellular adhesion molecule-3-grabbing non-integrin dendritic cells DLN GALT gut-associated lymphoid tissue HA Haemagglutinin highly-pathogenic avian influenza HPAI IAV IBDV IBV immunomodulation Infection Infectious Bronchitis Virus infectious bursal diease virus influenza A virus laboratory of genetics and physiology 2 LGP2 lipopolysaccharide Low pathogenic influenza LPAI LPS macrophage galactose binding lectin macrophage mannose receptor macrophages MDA5 Melanoma differentiation-associated protein 5 MGL MMR MPh mucosal NA NALT nasal associated lymphoid tissue NDV neuraminidase newcastle disease virus Pattern recognition receptors PRR respiratory tract retinoic acid-inducible gene I RIG-I Rt TLR Toll-like receptors. [DOI] 10.1016/j.dci.2013.03.008 PMC 바로가기 [Article Type] Review
Host and Microbial Factors in Regulation of T Cells in the IntestineReview Article Published on 2013-05-102023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] commensal bacteria dendritic cells FOXP3 intestine retinoic acid T cells Th17 [DOI] 10.3389/fimmu.2013.00141 PMC 바로가기 [Article Type] Review Article
Overweight and obese adult humans have a defective cellular immune response to pandemic H1N1 influenza A virusArticle Published on 2013-01-172023-06-23 Journal: Obesity (Silver Spring, Md.) [Category] 신종인플루엔자, [키워드] CD4+ T cells CD8+ T cells dendritic cells obesity overweight pH1N1 influenza [DOI] 10.1002/oby.20383 PMC 바로가기 [Article Type] Article
Intestinal binding of seasonal influenza A viruses to DC‐SIGN + CD68 + cellsArticle Published on 2012-07-132023-06-09 Journal: Influenza and Other Respiratory Viruses [Category] 신종인플루엔자, [키워드] dendritic cells intestine seasonal influenza viruses [DOI] 10.1111/j.1750-2659.2012.00402.x PMC 바로가기
SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1bResearch Article Published on 2012-01-122022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Accessory accessory protein activity acute respiratory syndrome Affect AP-1 binding Cell cells cellular chemokine co-immunoprecipitation cytokine dendritic cells downstream genes elevated ENCODE ERK expressing finding found functions Genome Host IL2 increase in Infected Infection inhibitor Interaction interferon isoform kinase lab led to MIP-1α monocyte mRNA level Pathogenesis pharmacological Phosphorylation physiological promoter Protein recruitment related reporter gene assay Runt RUNX1 SARS Coronavirus SARS virus SARS-CoV target gene transcription factor transcriptional activity Treatment unique upregulated upregulating upregulation yeast [DOI] 10.1371/journal.pone.0029542 PMC 바로가기 [Article Type] Research Article
Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis인터페론 조절 인자 8은 골수 세포 및 결핵 기간 동안 항원 제시 경로를 조절합니다Research Article Published on 2011-06-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] (major histocompatibility complex activate Activation allele Analysis Antigen presentation antigen processing Author binding binding site cellular pathway cellular pathways chromatin chromatin immunoprecipitation class Combination component Critical cytokine Defense dendritic cell dendritic cells differentiation early response endomembrane eQTLs expressed expression F2 Factor fixed functional Gene gene transcription GTPase GTPases histocompatibility complex Host–pathogen interaction identify IFNγ IL-12 IL12 immune response Infected Infection interferon gamma interferon regulatory factor interleukin intracellular pathogens intrinsic investigated IRF8 lipopolysaccharide LPS lung tissue lung tissues Lungs Macrophage macrophages major histocompatibility complex maturation member MHC mice Microarray Microarrays microbial motif mutant Mycobacterium tuberculosis myeloid myeloid cell myeloid cells ontogeny Pathogens pathway Pathways presentation priming progenitor cells promoter promoters Proteins pulmonary tuberculosis regulated Regulation represse required resistance to infection resistance to infections significantly Stimulation susceptible target transcript Transcription transcriptional treated Tuberculosis wild-type [DOI] 10.1371/journal.pgen.1002097 PMC 바로가기 [Article Type] Research Article
Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected MiceResearch Article Published on 2009-10-232022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] activate activated Activation Adaptive immune response allergic alveolar macrophage animal model Anti-viral Antigen Author BALB/c mice caused characterized correlated CoV dendritic cell dendritic cells deplete develop DLN draining lymph node Epidemic feature Human human disease human population humans immune response individual inefficient Infected Infection inhibitory inhibitory effect initial Liposome lung lymphopenia MA15 Macrophage mice morbidity and mortality mouse-adapted SARS-CoV Novel coronavirus occurred Patient Poor Prevent prolonged virus persistence PROTECT respiratory Respiratory disease response severe severe disease severe respiratory disease T cell response T cells Therapies TLR3 Toll-like receptor transfer treated virus virus clearance virus excretion virus-specific T cell [DOI] 10.1371/journal.ppat.1000636 PMC 바로가기 [Article Type] Research Article
DC-SIGN mediates avian H5N1 influenza virus infection in cis and in transArticle Published on 2008-06-302023-05-31 Journal: Biochemical and Biophysical Research Communication [Category] 조류인플루엔자, [키워드] DC-SIGN dendritic cells H5N1 Pseudotyped virus [DOI] 10.1016/j.bbrc.2008.06.078 PMC 바로가기 [Article Type] Article