The diagnostic accuracy of isothermal nucleic acid point-of-care tests for human coronaviruses: A systematic review and meta-analysis인간 코로나바이러스에 대한 등온 핵산 현장 진료 검사의 진단 정확도: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2020-12-182022-09-01 Journal: Scientific Reports [Category] MERS, 진단, [키워드] 95% CI Abbott Accuracy amplification applied article assessment Biochemistry bioRxiv Biotechnology calculate Cochrane Handbook coronavirus Coronaviruses COVID-19 COVID-19 patient CRISPR diagnose diagnostic Diagnostic accuracy Diagnostic specificities diagnostic specificity diagnostic test Diseases domains double-blinded evaluated focus Future guideline Handbook high risk identify isothermal isothermal amplification item Loop-mediated isothermal amplification medRxiv MERS Meta-analysis Microbiology Molecular biology Molecular medicine MOST nucleic acid Odds ratio offered on type Other patient cohorts patient selection peer-reviewed platform POCT point-of-care test purified RNA QUADAS-2 Quality reported Reporting Research reverse transcription review risk RNA extraction RNA purified RT-LAMP searched sensitivities sensitivity specificity systematic review systematic review and meta-analysis systematic reviews Test was used [DOI] 10.1038/s41598-020-79237-7 PMC 바로가기 [Article Type] Meta-Analysis
Addressing the relationship between perceived fear of COVID-19 virus infection and emergence of burnout symptoms in a sample of Egyptian physicians during COVID-19 pandemic: a cross-sectional studyResearch Published on 2020-12-172022-10-29 Journal: Middle East Current Psychiatry [Category] COVID-19, [키워드] Anxiety Burnout Burnout syndrome conducted correlated correlation COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 virus cross-sectional death Depression depressive depressive symptom Depressive symptoms domains Egypt Emotional exhaustion fear Fear of COVID-19 virus infection female HADS idea identify Infection Intervention inventory life Mental outbreak participant physical physician Physicians poor quality positively correlated Quality Quality of life reported Result robust scale Specific Stress Symptom Symptoms syndrome World Health Organization [DOI] 10.1186/s43045-020-00079-0 PMC 바로가기 [Article Type] Research
Physical Health, Media Use, and Mental Health in Children and Adolescents With ADHD During the COVID-19 Pandemic in AustraliaArticles Published on 2020-12-172022-10-30 Journal: Journal of Attention Disorders [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 95% CI activity ADHD Adolescent change Child children COVID-19 disorder domains Impact less loneliness media MOST negative and positive parent positive Psychological well-being Ratio reported Stress [DOI] 10.1177/1087054720978549 PMC 바로가기 [Article Type] Articles
The Impact of the Covid-19 Pandemic and the Lockdown on the Health and Living Conditions of Undocumented Migrants and Migrants Undergoing Legal Status RegularizationPublic Health Published on 2020-12-162022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] accumulated affected asked avoidance Care cohort study condition conducted consequence COVID-19 COVID-19 crisis cross-sectional cumulative domain domains group Health high risk highlight Impact lack less living conditions lockdown material migrant overlapped participant poor mental health Prevalence questionnaire respond risk seeking status Support Switzerland undergo undocumented was selected while [DOI] 10.3389/fpubh.2020.596887 PMC 바로가기 [Article Type] Public Health
Optimised genetic algorithm-extreme learning machine approach for automatic COVID-19 detection자동 COVID-19 감지를 위한 최적화된 유전자 알고리즘-극단적 학습 머신 접근 방식Research Article Published on 2020-12-152022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] Accuracy acute respiratory syndrome applied approach Brain Breast cancer carcinoma in situ caused Chest computed tomography chest X-ray Chest X-ray image Chest X-ray images computation Computed tomography coronavirus coronavirus disease COVID-19 criteria CT scan dataset deep deep learning detect domain domains effective Effectiveness evaluated Factor faster Features focus Genetic global pandemic healthy identify illnesses learning lung machine machine learning approach memory network Neural Principal component principal component analysis random reduce respiratory Severe acute respiratory syndrome Support support vector machine tested time-consuming vector X-ray [DOI] 10.1371/journal.pone.0242899 PMC 바로가기 [Article Type] Research Article
Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communicationsResearch Paper Published on 2020-12-152022-10-30 Journal: The Lancet Regional Health - Europe [Category] COVID-19, [키워드] Adults Attitude Attitudes towards vaccines benefit children COVID-19 COVID-19 guidelines COVID-19 pandemic Covid-19 social study COVID-19 vaccine cross-sectional determinant domain domains Effects examined Factor Factors female gender finding flu vaccine foundation funding Government group Health messaging identify individual Innovation Intention knowledge large sample natural immunity negative network poor compliance population immunity predictor Public public health public health communication receive refusal regression analysis reported risk Side effect socio-demographic supported UCL vaccinate vaccination Vaccine vaccine for COVID-19 vaccine refusal Wellcome Trust women [DOI] 10.1016/j.lanepe.2020.100012 PMC 바로가기 [Article Type] Research Paper
Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding DomainsACE2가 있거나 없는 SARS-CoV-2 스파이크의 Cryo-EM 구조는 수용체 결합 도메인의 엔도솜 위치를 매개하는 pH 의존적 스위치를 나타냅니다Article Published on 2020-12-092022-09-12 Journal: Cell Host & Microbe [Category] MERS, SARS, 진단, [키워드] absence ACE2 ACE2 binding ACE2 receptor adopted Affect alteration binding antibody conformation COVID-19 Cryo-electron microscopy domain domains endosomal endosomal entry engage facilitate human ACE2 receptor immune evasion Interaction occur Pathways pH-dependent switch positioning RBD RBDs Receptor-binding domain Receptor-binding domain (RBD) required SARS-CoV-2 SARS-CoV-2 spike serological spike structural rearrangement Structure switch trimer type 1 fusion machine. virus entry [DOI] 10.1016/j.chom.2020.11.004 PMC 바로가기 [Article Type] Article
An Educational Bioinformatics Project to Improve Genome AnnotationMicrobiology Published on 2020-12-072022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Amino acid Analysis annotation approach automated Bacterial binding bioinformatics can be used cells cellular characterization classroom Complete Course database detect determine Differential gene expression domains education Enough Evidence example experimental evidence functions Genome genome annotation help hypothetical hypothetical protein identify IMPROVE include knowledge lack ligands mRNA expression Open reading frame Phylogenetic predict Program Protein Proteins provide random resource sequence sequence similarity student Support training video Undergraduate variety while X-ray crystallography YouTube [DOI] 10.3389/fmicb.2020.577497 PMC 바로가기 [Article Type] Microbiology
A rapid review of home-based activities that can promote mental wellness during the COVID-19 pandemicCOVID-19 전염병 동안 정신 건강을 증진할 수 있는 재택 활동에 대한 신속한 검토Research Article Published on 2020-12-032022-09-10 Journal: PLoS ONE [Category] MERS, 임상, [키워드] activities activity Affect Analysis association benefit checked CINAHL Cohen’s d conducted consequence controlled trials COVID-19 pandemic data extraction described disorder domain domains Effect eligible Evidence examined exercise expressed global health guideline help IMPROVE include individual Isolation lead measure Mental mental health mental health professional mental health professionals Meta-analysis mitigate muscle relaxation non-randomized studies non-randomized study outcome performed potential risk progressive muscle relaxation promote public health measure public health measures quarantine Randomized controlled trial Randomized controlled trials reported Result resulting risk of bia social distancing social isolation Stress Symptoms synthesis unique were assessed were excluded while yoga [DOI] 10.1371/journal.pone.0243125 PMC 바로가기 [Article Type] Research Article
The Global and Local Distribution of RNA Structure throughout the SARS-CoV-2 GenomeGenome Replication and Regulation of Viral Gene Expression Published on 2020-12-022022-10-30 Journal: Journal of Virology [Category] COVID-19, [키워드] acute respiratory syndrome affected Analysis analyzed approach base pair content cellular coding region comparison complex coronavirus COVID-19 domain domains element exceptional feature functional Genome genomic genomic RNA global pandemic gRNA HCV hepatitis C virus highest in silico knowledge motif Open reading frame ORF ORFs predict predicted provide Region regions resulting RNA RNA genome RNA structure RNA structures RNA transcripts RNA virus RNA viruses SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 RNA secondary structure sgRNA stability structural stability Structure structured region targets the disease the SARS-CoV-2 unique viral genome viral genomes viral infection Viral RNA viral RNAs while [DOI] 10.1128/JVI.02190-20 PMC 바로가기 [Article Type] Genome Replication and Regulation of Viral Gene Expression