Estimating the Number of COVID-19 Cases and Impact of New COVID-19 Variants and Vaccination on the Population in Kerman, Iran: A Mathematical Modeling StudyCOVID-19 사례 수와 새로운 COVID-19 변종 및 백신 접종이 이란 케르만 인구에 미치는 영향 추정: 수학적 모델링 연구Article Published on 2022-04-262022-09-11 Journal: Computational and Mathematical Methods in Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] affected Alpha alpha and delta variants Alpha variant Analysis average calculated calibrated the model case finding chain conducted Contact Contact tracing COVID-19 COVID-19 cases death deaths delta variant dominant effective Hospitalization hospitalizations Impact infected case infected cases Infection interval Iran Isolation limitation Markov Markov chain modeling New number number of infected per day Population predict Prevent promote public education quarantine reducing reported reproductive SEIR Self-isolation social distancing susceptible-exposed-infected-removed the epidemic vaccination Vaccine variant was used [DOI] 10.1155/2022/6624471 PMC 바로가기 [Article Type] Article
Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination eventsSARS-CoV-2 Omicron의 다양한 스파이크 유전자 돌연변이를 추적하여 여러 변이체 간 재조합 이벤트를 식별합니다.Article Published on 2022-04-262022-09-11 Journal: Signal Transduction and Targeted Therapy [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Alpha Amino acid attribute change characteristic Co-infection Delta dominant epitope Epitopes Evolution of SARS-CoV-2 Frequency Genome identify in some include mechanism modifications monitoring MOST Mutation nine omicron other variant other variants pandemic of COVID-19 Pathogens phylogenetically Recognition recombinants Recombination recombination event Revertant SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes scanning South Africa spike gene Spike protein subsequent the spike protein Vaccine variant variants variants of interest viral pathogens VOCs VOIs [DOI] 10.1038/s41392-022-00992-2 PMC 바로가기 [Article Type] Article
Structural and functional impact by SARS-CoV-2 Omicron spike mutationsSARS-CoV-2 오미크론 스파이크 돌연변이에 의한 구조적 및 기능적 영향Article Published on 2022-04-262022-09-11 Journal: Cell Reports [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alter antigenic antigenic structure cellular tropism coronavirus country CP: Molecular biology cryo cryo-EM dominant evade full-length functional host immunity host receptor membrane fusion Molecular biology mutations N-terminal domain Neutralizing antibodies not seen omicron Omicron variant other variants prevalent Protein Receptor-binding domain S protein SARS-CoV-2 sequence severe acute respiratory syndrome Coronavirus spike mutation Spike protein Structure the receptor-binding domain the S protein variant variants [DOI] 10.1016/j.celrep.2022.110729 PMC 바로가기 [Article Type] Article
Waning effectiveness of CoronaVac in real life: A retrospective cohort study in health care workers실생활에서 코로나백의 약화 효과: 의료 종사자를 대상으로 한 후향적 코호트 연구Article Published on 2022-04-202022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI adjusted Alpha Alpha variant association booster dose booster doses clinical trials conducted CoronaVac COVID-19 COVID-19 disease COVID-19 infection COVID-19 infections COVID-19 vaccine Cox regression defined demonstrated determine dominant dose doses Effectiveness follow-up period groups Health care Health care worker health care workers Inactivated vaccine incidence rate İstanbul positive PCR test rate ratio receive receiving reduce retrospective cohort study SARS-COV-2 infection second dose test result the vaccine Turkey university hospital vaccination Vaccine vaccine effectiveness variant variants were used [DOI] 10.1016/j.vaccine.2022.03.032 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Delta and Omicron Variants Surge in Curitiba, Southern Brazil, and Its Impact on Overall COVID-19 Lethality브라질 남부 쿠리티바에서 SARS-CoV-2 델타 및 오미크론 변종 급증, 전체 COVID-19 치사율에 미치는 영향Article Published on 2022-04-142022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] affected Analysis assist Brazil Combination coronavirus correlated Course Coverage COVID-19 COVID-19 case COVID-19 pandemic Delta delta variant Diagnosis diagnostic diagnostic techniques and procedures dominant effort Environment evaluate evaluated fraction genomic Genomic surveillance genotyping Healthcare system Impact Infection infections less lethality lethality rate Multiple infection observé omicron pandemic performed positive public health reduction in RT-qPCR SARS-CoV-2 Screening Spread state strain Strains Surveillance symptomatic and asymptomatic translated university vaccination variant [DOI] 10.3390/v14040809 PMC 바로가기 [Article Type] Article
Design of SARS-CoV-2 Variant-Specific PCR Assays Considering Regional and Temporal Characteristics지역 및 시간적 특성을 고려한 SARS-CoV-2 변이체 특이적 PCR 분석 설계Article Published on 2022-04-122022-09-11 Journal: Applied and Environmental Microbiology [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Accuracy Algorithm Alpha Alpha variant Amplicon Analysis applicability applied Community Consistency contribute COVID-19 pandemic D950N Delta delta variant dominant Epidemiology evaluate Genome sequencing geographical region GISAID database help in silico in silico analysis Local marker monitoring Mutation mutations Next-generation sequencing NGS P681R PCR PCR assay PCR assays Prevalence PRIMES public health reduced Regional robust SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Sensitivity and specificity sequence sequences sequencing technology Support Surveillance T19R T478K Temporal track unique USA variant variants variants of concern variants of interest VOCs VOIs Wastewater-based epidemiology wild type [DOI] 10.1128/aem.02289-21 PMC 바로가기 [Article Type] Article
Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?SARS CoV-2 오미크론 변종은 델타 변종보다 더 치명적이고 전염성이 있습니까?Review Published on 2022-04-112022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus affected Brazil breakthrough infections catastrophic caused changed Characteristics Community Consequences contagious coronavirus country COVID-19 death Delta delta variant dominant fatality FIVE France genetic variants greater increased mortality India Infection information meta-data omicron Omicron variant Omicron variants other variants outbreak pandemic Preliminary data reported SARS CoV-2 SARS-CoV-2 SARS-CoV-2 variant selected severe acute respiratory syndrome Coronavirus severity severity and mortality South Africa The United States Transmissibility United Kingdom United States vaccination variant variants variants of concern [DOI] 10.3390/ijerph19084586 PMC 바로가기 [Article Type] Review
Projecting the Pandemic Trajectory through Modeling the Transmission Dynamics of COVID-19COVID-19의 전파 역학 모델링을 통한 팬데믹 궤적 예측Article Published on 2022-04-092022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] circulating classic Community compartmental model compartmental modeling Course COVID-19 COVID-19 pandemic Critical deaths disease Disease progression disease severity Diseases dominant doses Dynamics effective Effectiveness Efficiency epidemiological Epidemiology extension groups immunization result infected individuals Infection Local majority mathematical Mild modeling Modification modifications observation observations omicron Omicron variant pandemic Pandemics population groups powerful tool public health reduce reduction in single variant SIRS Spread Support supported Transmissibility Transmission Transmission dynamics understanding vaccination Vaccine variant virulent [DOI] 10.3390/ijerph19084541 PMC 바로가기 [Article Type] Article
Mutational scanning of spike RBD protein for enhanced ACE2 affinity emerging Southeast Asia in the late transmission phase후기 전송 단계에서 동남아시아 신흥 ACE2 친화력 향상을 위한 스파이크 RBD 단백질의 돌연변이 스캐닝Article Published on 2022-04-072022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] ACE2 ACE2 binding analyzed Asia binding changed Cluster conserved coronavirus COVID-19 COVID-19 pandemic Deleterious Diversity dominant effective Epitopes evaluate facilitate higher affinity hotspot Human Human Security in silico MD simulations measure mutated Mutation Neutralizing Outbreaks Protein Quality of life RBD mutation RBD protein RBD region Salt Bridge SARS-CoV-2 SARS-CoV-2 virus stability the disease the RBD the SARS-CoV-2 virus Transmission transmitted Treatment vaccination Variation virus [DOI] 10.1038/s41598-022-09999-9 PMC 바로가기 [Article Type] Article
Identification of Entry Inhibitors against Delta and Omicron Variants of SARS-CoV-2SARS-CoV-2의 Delta 및 Omicron 변이체에 대한 진입 억제제 식별Article Published on 2022-04-062022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 approved authentic SARS-CoV-2 virus Beta block Compound coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Delta Delta variants dolutegravir domain dominant drug drug library EC50 value EC50 values Entry inhibitor entry inhibitors Etravirine identification Infection inhibited inhibitor inhibitors molecular docking molecular interaction neutralization test neutralizing activities Neutralizing activity omicron outbreak plaque reduction neutralization Plaque reduction neutralization test pseudovirus pseudovirus entry pseudoviruses RBD RBD domain receptor Receptor-binding domain residue robust SARS-CoV-2 SARS-CoV-2 virus SARS-CoV2 severe acute respiratory syndrome Coronavirus significantly Spike protein Spike proteins the RBD the receptor-binding domain These data variants Vero E6 Vero E6 cell VERO E6 cells viral entry viral spike protein viral variant was used [DOI] 10.3390/ijms23074050 PMC 바로가기 [Article Type] Article