Single- and Two-Stage, Closed-Tube, Point-of-Care, Molecular Detection of SARS-CoV-2SARS-CoV-2의 1단계 및 2단계, 폐쇄관, 현장 진료, 분자 검출Article Published on 2021-09-282022-09-11 Journal: Analytical Chemistry [Category] SARS, 치료기술, 치료제, [키워드] Amplicon amplicons amplification analytical sensitivity carried Chain Reaction COVID-19 pandemic Cycling described detection diagnostic test effective first stage fluorescent Instrumentation Isolation isothermal amplification LAMP loop mediated isothermal amplification molecular N gene nasopharyngeal swabs not need nucleic acid ORF1ab oropharyngeal swabs Patient PCR assays polymerase chain polymerase chain reaction primer processed provide quantitative polymerase chain reaction reagent real time Region reverse transcription RNA RT-LAMP RT-qPCR RT-RPA Saliva SARS-CoV-2 SARS-CoV-2 test sensitivity Support tested threshold Vaccine Viral load viral loads virus virus genome [DOI] 10.1021/acs.analchem.1c03016 PMC 바로가기 [Article Type] Article
A unique case of Miller Fisher-Guillain-Barré overlap syndrome in a liver transplant recipient간 이식 환자의 Miller Fisher-Guillain-Barré 중첩 증후군의 독특한 사례Case Reports Published on 2021-09-222022-09-10 Journal: Journal of Neurovirology [Category] MERS, SARS, 변종, [키워드] Acute respiratory failure Chain Reaction Complication COVID-19 COVID-19 infection cranial Cranial nerve demonstrated descending Descending paralysis diagnosed Diagnosis Diaphragm electromyography facial Fisher Fisher syndrome Guillain-Barré syndrome Guillain-barrè syndrome highlight Immunocompromised patient Infection liver liver transplant Liver transplantation Miller Miller fisher syndrome Nasopharyngeal swab nasopharyngeal swabs Nerve conduction nerve conduction study neurologic Neurological complication Neurological complications occur ophthalmoplegia overlap overlap syndrome paralysis patients plasma plasma exchange polymerase chain polymerase chain reaction Polyneuropathy positive predominant progressed quadriparesis recipients Respiratory failure SARS-CoV-2 IgG serology solid organ solid organ transplant Symptom syndrome thought Treatment unique variant [DOI] 10.1007/s13365-021-01015-6 PMC 바로가기 [Article Type] Case Reports
Rapid Screening of COVID-19 Directly from Clinical Nasopharyngeal Swabs Using the MasSpec PenMasSpec 펜을 사용하여 임상 비인두 면봉에서 직접 COVID-19의 신속한 스크리닝Article Published on 2021-09-212022-09-11 Journal: Analytical Chemistry [Category] SARS, 치료기술, [키워드] Accuracy Analysis analyzed Asymptomatic Asymptomatic individuals Chain Reaction Classifier clinical COVID-19 COVID-19 disease diagnostic test diagnostic tests electrospray ionization ESI gold gold standard individual individuals information ionization mass spectrometry minute moderate to severe Nasopharyngeal swab nasopharyngeal swabs outbreak patients with moderate PCR PCR-negative PCR-positive PCR-positive patient Pen polymerase chain polymerase chain reaction positive profile profiles Rapid reagents representing SARS-COV-2 infection Screening sensitivity severe symptom specificity statistical Swab symptomatic symptomatic COVID-19 this system while yielding [DOI] 10.1021/acs.analchem.1c01937 PMC 바로가기 [Article Type] Article
High SARS-CoV-2 viral load is associated with a worse clinical outcome of COVID-19 diseaseShort Communications Published on 2021-09-212022-10-28 Journal: Access Microbiology [Category] COVID-19, [키워드] Admission age association Asthma Biomarker cardiovascular disease chronic obstructive Clinical outcome clinical parameter Clinical prognosis clinically Cohort COVID-19 COVID-19 disease COVID-19 severity death determine diabetes Disease progression disease severity Evolution Factor Final Genome hospital Hospitalization Host hypertension in viral Infection intensive care unit Lung disease Mild moderate nasopharyngeal swabs obesity oligonucleotide ORF1ab outbreak outcome Oxygen therapy pandemic parameter Patient progression pulmonary disease risk factor Risk factors SARS-CoV-2 viral load SARS-CoV-2-infected patient SARS-CoV-2-infected patients severe COVID-19 severity Sex Spain statistically significant variant Viral load Virological [DOI] 10.1099/acmi.0.000259 PMC 바로가기 [Article Type] Short Communications
Immunological assessment of SARS-CoV-2 infection in pregnancy from diagnosis to delivery: A multicentre prospective study진단에서 전달까지 임신 중 SARS-COV-2 감염의 면역 학적 평가 : 다기관 전향 연구Observational Study Published on 2021-09-202022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] 95% CI Abbott Abbott SARS-CoV-2 IgG All participants Antenatal anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody antibody Antibody Response Antibody responses Architect Asymptomatic baseline Blood Cohort Combination conducted Cord blood demonstrated detectable Diagnosis Elecsys Europe evidence of fetal FIVE gestation hospital IgG IgG antibodies IgG SARS-CoV-2 antibodies IgG SARS-CoV-2 antibody IgM IgM antibodies immunoassay independent Informed Maternal maternity hospitals Migration multicentre Naso-pharyngeal swab naso-pharyngeal swabs Nasopharyngeal swab nasopharyngeal swabs Neonate observational study Participants passive immunity platform positive Pregnancy pregnant women Prevalence prospective observational study Prospective Study provided raising remained responses Result RNA Roche RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV2 serological assays serological assessment serological evidence serological response serological test seropositive serum serum sample Seven symptomatic the antibody response Transplacental umbilical Umbilical cord Viral Viral RNA was measured was obtained was performed women written consent [DOI] 10.1371/journal.pone.0253090 PMC 바로가기 [Article Type] Observational Study
Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation바이러스 열 불 활성화를 포함한 탄력성 SARS-COV-2 진단 워크 플로Research Article Published on 2021-09-152022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] CDC clinical sample clinical samples combinations demonstrated detect develop diagnostics EUA heat inactivation inactivated Laboratory master mix MINI Nasopharyngeal swab nasopharyngeal swabs NEB nucleic acid Nucleic acid detection Omega PCR plaque assays protocol protocols provided Qiagen qPCR RdRP reagent reagents RNA RNA extraction RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleic acid SARS-CoV-2 testing sensitivity significant differences TaqMan ThermoFisher Scientific titres Treatment Universal variant Viral viral DNA [DOI] 10.1371/journal.pone.0256813 PMC 바로가기 [Article Type] Research Article
Platinum chloride-based viability RT-qPCR for SARS-CoV-2 detection in complex samples복잡한 샘플에서 SARS-CoV-2 검출을 위한 염화백금 기반 생존율 RT-qPCRArticle Published on 2021-09-132022-09-10 Journal: Scientific Reports [Category] SARS, 치료기술, 치료제, [키워드] amplification Analysis approach Biological techniques buffer complement Complete complex Compound Contact tracing COVID-19 detect develop Environmental microbiology Environmental sciences FIVE foster genomic RNA inactivated indicated infection risk Infectious virus inoculated marker Microbiology molecular Molecular biology molecular markers Nasopharyngeal swab nasopharyngeal swabs non-infectious outbreak Particle Platinum positive Prevent Prevention and control provide qPCR RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 particle SARS-CoV-2 RNA screened social movement specimen Spread Stool targets tested Urine viability Viral viral shedding Virology viruses wastewater [DOI] 10.1038/s41598-021-97700-x PMC 바로가기 [Article Type] Article
Diagnostic accuracy and acceptability of molecular diagnosis of COVID-19 on saliva samples relative to nasopharyngeal swabs in tropical hospital and extra-hospital contexts: The COVISAL studyResearch Article Published on 2021-09-132022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] amplification Analysis analyzed Asymptomatic conditions conducted COVID-19 Culture defined Diagnostic accuracy E gene enrolled evaluate French hospital Mild symptom Molecular diagnosis N gene nasopharyngeal nasopharyngeal sample Nasopharyngeal samples Nasopharyngeal swab nasopharyngeal swabs Negative predictive value Older PCR amplification Person Population positive positive patient Prospective Study RdRp gene RT-PCR Saliva saliva test salivary sensitivity Sensitivity and specificity specific target gene target gene tropical variety [DOI] 10.1371/journal.pone.0257169 PMC 바로가기 [Article Type] Research Article
Non-intrusive wastewater surveillance for monitoring of a residential building for COVID-19 casesCOVID-19 사례에 대한 주거용 건물 모니터링을 위한 비침습적 폐수 감시Article Published on 2021-09-102022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, 치료제, [키워드] absence building clinical testing Cluster Community complement Concentration COVID-19 COVID-19 case COVID-19 case detection COVID-19 cases COVID-19 transmission diarrhea Disease prevalence Epidemiology FIVE Frequency healthcare facility healthy highlighting household contact intensity MONITOR Nasopharyngeal swab nasopharyngeal swabs Non-intrusive COVID-19 surveillance PCR tests positive quarantine reported Respiratory illness return risk of COVID-19 SARS-CoV-2 SARS-CoV-2 spikes Singapore spike Stool Surveillance symptomatic tested the SARS-CoV-2 Transmission utility virus Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2021.147419 PMC 바로가기 [Article Type] Article
Soccer in the time of COVID-19: 1 year report from an Italian top league club, March 2020–February 2021COVID-19 시대의 축구: 이탈리아 최고 리그 클럽의 1년 보고서, 2020년 3월–2021년 2월From the Field Published on 2021-09-082022-09-11 Journal: Epidemiology and Infection [Category] SARS, 치료기술, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus club coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outbreak event Football hospitalised Immunoglobulin Immunoglobulin G Italian Italy lockdown Nasopharyngeal swab nasopharyngeal swabs National Outbreaks pandemic Prevalence respiratory risk SARS-CoV-2 SARS-COV-2 infection serological Serological tests Seven sport team took place top league [DOI] 10.1017/S0950268821002065 PMC 바로가기 [Article Type] From the Field