Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumoniaResearch Article Published on 2018-06-072022-11-01 Journal: JCI Insight [Category] Coronavirus, SARS, [키워드] absence activate activated activated macrophage Activation acute respiratory syndrome adaptive airway Antigen caused coronavirus CoV Heterologous IFN-I immune Immunity immunology independent infiltration Inflammatory inflammatory monocyte influenza A virus Innate immunity inspired air Local lung Lung infection Lungs monocyte Monocytes morbidity Mortality mucosal mucosal immune murine nasal nasal mucosa NK cell Particle pathogen Pneumonia priming PROTECT protective immunity provide pulmonary lymph nodes reduced SARS-CoV Signaling significantly these cell Type I IFN viral infections Virology virus virus infection virus pneumonia [DOI] 10.1172/jci.insight.99025 PMC 바로가기 [Article Type] Research Article
Anti-HBV response to toll-like receptor 7 agonist GS-9620 is associated with intrahepatic aggregates of T cells and B cellsArticle Published on 2018-05-012023-06-18 Journal: Journal of hepatology [Category] B형 간염, Fulltext, [키워드] B cell CD8 T cell Chimpanzee animal model Hepatitis B virus immunomodulation interferon-alpha interferon-stimulated gene Lymphocyte aggregate NK cell Tertiary lymphoid structure. TLR7 [DOI] 10.1016/j.jhep.2017.12.008 PMC 바로가기
Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and LiverArticle Published on 2017-12-012023-06-03 Journal: Gastroenterology [Category] B형 간염, Fulltext, [키워드] cccDNA, covalently closed circular DNA CHB, chronically HBV infected CXCL10 ELISA, enzyme-linked immunosorbent assay ETV, entecavir hAlb, human Albumin HBcAg, hepatitis B core antigen HBe HBe, hepatitis B envelope HBs, hepatitis B surface HBsAg, hepatitis B surface antigen HBV, hepatitis B virus HCC, hepatocellular carcinoma HIS, human immune system HUHEP, human hepatocytes IFN, interferon IL10 LPC, liver progenitor cell mouse model NK cell NK, natural killer NUC, nucleos(t)ide analog PD-1, programmed death-1 PD-L1, PD-1 ligand qPCR, quantitative polymerase chain reaction TLR, Toll-like receptor TNF, Tumor Necrosis Factor TRAIL, TNF-related apoptosis-inducing ligand death receptor wpi, week post-infection [DOI] 10.1053/j.gastro.2017.08.034 PMC 바로가기 [Article Type] Article
Hepatitis B virus infection and the immune response: The big questionsReview Published on 2017-06-012023-06-15 Journal: Best practice & research. Clinical gastroenterology [Category] B형 간염, [키워드] adaptive B cell hepatitis B immune response Innate Kupffer cell NK cell T cell. [DOI] 10.1016/j.bpg.2017.05.003 PMC 바로가기 [Article Type] Review
The protective effects of intranasal administration of IL-12 given before influenza virus infection and the negative effects of IL-12 treatment given after viral infectionArticle Published on 2016-09-012023-06-24 Journal: Journal of medical virology [Category] 신종인플루엔자, [키워드] IL-12 influenza virus infection myeloid-derived suppressor cell (MDSC). NK cell [DOI] 10.1002/jmv.24494 PMC 바로가기
HLA-C and KIR combined genotype as new response marker for HBeAg-positive chronic hepatitis B patients treated with interferon-based combination therapyArticle Published on 2016-08-012023-06-18 Journal: Journal of viral hepatitis [Category] B형 간염, [키워드] combination therapy hepatitis B HLA-C KIR NK cell peg-interferon-alfa. [DOI] 10.1111/jvh.12525 PMC 바로가기
Intranasal administration of poly-gamma glutamate induced antiviral activity and protective immune responses against H1N1 influenza A virus infectionResearch Published on 2015-10-062023-06-07 Journal: Virology Journal [Category] 신종인플루엔자, [키워드] antiviral activity Cytotoxic T cells Influenza virus NK cell Poly-gamma glutamate [DOI] 10.1186/s12985-015-0387-0 PMC 바로가기 [Article Type] Research
Phenotypic and functional analyses of NK and NKT-like populations during the early stages of chikungunya infectionOriginal Research Published on 2015-09-012023-08-30 Journal: Frontiers in Microbiology [Category] E형 간염, [키워드] Chikungunya cytotoxicity NK cell NKT-like cell perforin [DOI] 10.3389/fmicb.2015.00895 PMC 바로가기 [Article Type] Original Research
Varicella zoster virus immunity: A primerReview Published on 2015-06-012023-06-01 Journal: The Journal of Infection [Category] 두창, 수두, 홍역, [키워드] antibody CD4+ T cell Chickenpox immunodeficiency interferon NK cell shingles VZV zoster. [DOI] 10.1016/j.jinf.2015.04.015 PMC 바로가기 [Article Type] Review
Pathogenic Mouse Hepatitis Virus or Poly(I:C) Induce IL-33 in Hepatocytes in Murine Models of HepatitisResearch Article Published on 2013-09-132022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Acute liver injury addition administration alarmin association cellular controls cytokine down-regulated expressed expressing expression Hepatitis hepatocyte IL-33 in viral Infection involved led to liver Liver injury mice microenvironment Model mouse mouse hepatitis virus murine NK cell NK cells NKT NKT cells over-expressed pathogenic Pathologies Patient poly(I:C post infection pro-inflammatory cytokine receptor Regulation remained sera sinusoidal endothelial cell TLR3 treated up-regulated Vascular vascular endothelial cell Viral hepatitis [DOI] 10.1371/journal.pone.0074278 PMC 바로가기 [Article Type] Research Article