Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical frameworkLetter to the Editor Published on 2020-10-272022-10-29 Journal: Journal of Otolaryngology - Head & Neck Surgery [Category] COVID-19, MERS, SARS, [키워드] Abstract aerosol-generating procedure approach Asymptomatic COVID-19 Betadine COVID-19 COVID-19 pandemic current effort filtration healthcare worker Measures mitigate mucosal nasal nasopharynx Numerous patients performed povidone-iodine prophylactic treatment Prophylaxis protocol raised reduce respiratory viruses risk SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 transmission Tolerance Upper Aerodigestive tract virus [DOI] 10.1186/s40463-020-00474-x PMC 바로가기 [Article Type] Letter to the Editor
Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analysesArticle Published on 2020-10-272022-10-04 Journal: Scientific Reports [Category] MERS, 유전자 메커니즘, 임상, [키워드] Analysis association Bacillus BCG BCG vaccination benefit boost clinical trial co-morbidities confounding variables correlation country COVD-19 COVID-19 COVID-19 outbreak death rate Diseases epidemiological epidemiological finding Evidence Health policy incidence of COVID-19 infection with SARS-CoV-2 initial Innate immunity Mortality Numerous Prevalence Prevent protection provide reduced Registered Respiratory tract diseases SARS-CoV-2 severity of COVID-19 significantly smoking Spread supported thought Tuberculosis Vaccine variable while [DOI] 10.1038/s41598-020-75491-x PMC 바로가기 [Article Type] Article
Insights into SARS-CoV-2, the Coronavirus Underlying COVID-19: Recent Genomic Data and the Development of Reverse Genetics SystemsInsight Review Published on 2020-10-242022-10-30 Journal: The Journal of General Virology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory disease acute respiratory syndrome Analysis can be used coronavirus coronavirus disease COVID-19 development Evolution example Features functions generate genetics genome sequence genomic study Genomics globe host range identify insight marker molecular Numerous pandemic pathogen Protein raised recent related virus reverse genetics SARS-CoV SARS-CoV-2 sequence sequence information Spread System transmissibility of SARS-CoV-2 viral genome virulence viruses WHO World Health Organization [DOI] 10.1099/jgv.0.001458 PMC 바로가기 [Article Type] Insight Review
Zinc and Copper Ions Differentially Regulate Prion-Like Phase Separation Dynamics of Pan-Virus Nucleocapsid Biomolecular CondensatesArticle Published on 2020-10-182022-10-28 Journal: Viruses [Category] COVID-19, [키워드] aerosol droplet aerosol droplets aggregate aggregates Analysis antiviral responses benefit bioinformatics biomolecular condensate cellular condensate conserved contribute copper deregulation disease disease-causing Diseases domain Dynamics eliminated feature function functions Gene Expression genomic RNA hallmark homeostasis Infection insoluble interfere Ion liquid-liquid phase separation mechanism membraneless organelle Meta-analysis modify modulate morphology neurodegenerative Neurodegenerative disease Neurological disease Neurological diseases nucleocapsid nucleocapsid protein Numerous organelle ortholog pan-virus persistence phase physiological plaque prion-like disordered protein domain promote Protein protein domain RBD RBDs Regulation Replication representing required Research responsible retrovirus RNA-binding domain separation stress granule therapeutic viral genomic RNA Viral protein virus virus infection vRNA while Zinc zinc finger motif [DOI] 10.3390/v12101179 PMC 바로가기 [Article Type] Article
Identifying Pathways and Networks Associated With the SARS-CoV-2 Cell Receptor ACE2 Based on Gene Expression Profiles in Normal and SARS-CoV-2-Infected Human TissuesMolecular Biosciences Published on 2020-10-162022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] ACE2 ACE2 expression angiotensin-converting enzyme 2 Cancer Cell Clinical outcome correlation ESR1 ESR2 estrogen receptor exceeded excessive immune response expression expression level female females gene co-expression network gene expression profile Gene expression profiles gene set enrichment analysis growth had no healthy host cell receptor Human human tissue human tissues identifying immune Immune cell immune defense Immune signatures involved male males mechanism metabolism network normal Numerous other diseases pathway positive profile proliferation receptor robust SARS-CoV-2 SARS-CoV-2 cell receptor SARS-COV-2 infection significant difference significantly susceptible the SARS-CoV-2 tissue tissues upregulated upregulation [DOI] 10.3389/fmolb.2020.568954 PMC 바로가기 [Article Type] Molecular Biosciences
Religion and Faith Perception in a Pandemic of COVID-19Original Paper Published on 2020-10-122022-10-30 Journal: Journal of religion and health [Category] Coronavirus, MERS, SARS, [키워드] coronavirus COVID-19 COVID-19 pandemic emotional ENhance examined Faith Health impacted Numerous outcomes pandemic Perception religion Spirituality Spread virus [DOI] 10.1007/s10943-020-01088-3 PMC 바로가기 [Article Type] Original Paper
Pathophysiology of Cardiovascular Complications in COVID-19Physiology Published on 2020-10-092022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] addition available data cardiometabolic conditions cardiovascular cardiovascular complication cardiovascular complications cardiovascular disease chronic cardiovascular Clinical course coagulation disorder Comorbidity Complication COVID-19 CVD Cytokine release syndrome de novo disease driving dysregulation Follow-up identify increased risk increasingly Infection Inflammatory Injury molecular Mortality Numerous older population pathophysiology pathway Patient patients with COVID-19 pediatric Pediatric Inflammatory Multisystem Syndrome protocol RAAS risk risk factor SARS-CoV-2 virus shown syndrome targets thrombosis treat Treatment with COVID-19 [DOI] 10.3389/fphys.2020.575600 PMC 바로가기 [Article Type] Physiology
Correlation of ELISA method with three other automated serological tests for the detection of anti-SARS-CoV-2 antibodiesResearch Article Published on 2020-10-062022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Abbott anti-SARS-CoV-2 antibody approved automated Centaur characteristic COVID-19 outbreak diagnostic DiaSorin early diagnosis ELISA Emergency use Emergency use authorization estimate EUA facilitated health emergency highlight immunoassay Numerous performed positive Public random Roche SARS-CoV-2 serologic antibody serological test Siemen tested Total [DOI] 10.1371/journal.pone.0240076 PMC 바로가기 [Article Type] Research Article
Current treatment approaches for COVID-19 and the clinical value of transfusion-related technologiesReview article Published on 2020-10-012022-10-05 Journal: Transfusion and apheresis science : official journ [Category] SARS, 치료법, [키워드] antiviral therapy Beta Blood caused Clinical practice convalescent plasma coronavirus COVID-19 COVID-19 infection current disease Health Immunomodulatory agents Infection Intervention mesenchymal stem cell Numerous patients with COVID-19 Plasmapheresis potential therapies SARS-CoV-2 specific treatment Therapeutic approach Treatment treatment approach virus [DOI] 10.1016/j.transci.2020.102839 [Article Type] Review article
Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3Article Published on 2020-09-282022-10-29 Journal: SLAS discovery : advancing life sciences R & D [Category] COVID-19, SARS, [키워드] ADP-ribose antiviral drug antiviral drug target approach atomic resolution AutoDock binding cellular Compound compounds coronavirus COVID-19 differential scanning fluorimetry domain drug DSF evade examined identify initial Ligand Mac1 macrodomain molecular molecular basis monophosphate nonstructural protein 3 nucleotides Numerous performed probe SARS-CoV-2 small molecule Steroids temperature the SARS-CoV-2 thermal shift [DOI] 10.1177/2472555220960428 PMC 바로가기 [Article Type] Article