Viral load of SARS-CoV-2 Omicron is not high despite its high infectivityArticle Published on 2022-11-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome caused cell receptor coronavirus coronavirus disease COVID-19 Delta delta variant examined Factors Genotype genotyping Immune escape median melting curve analysis nasopharyngeal no significant difference omicron Omicron variant Patient PCR performed polymerase chain Quantitative replaced SARS-CoV-2 Sequencing Spread Transmissibility two group variant Viral load virus [DOI] 10.1002/jmv.27974 PMC 바로가기
Breakthrough COVID-19 cases despite prophylaxis with 150 mg of tixagevimab and 150 mg of cilgavimab in kidney transplant recipientsArticle Published on 2022-11-012022-11-15 Journal: American journal of transplantation : official jou [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory distress Admission antibody assist carried clinical research/practice Combination COVID-19 COVID-19 case died dose examined in vitro Infection infection and infectious agents-viral infection and infectious agents-viral: SARS-CoV-2/COVID-19 Infectious disease injection intensive care intramuscular kidney transplant recipient Neutralizing activity Omicron variant Patient patients preexposure prophylaxis Prophylactic prophylactic strategy Prophylaxis PROTECT Protective required SARS-CoV-2 sequencing SARS-CoV-2 variant serum solid organ transplantation symptomatic syndrome tested variant [DOI] 10.1111/ajt.17121 PMC 바로가기
Resistance mutations in SARS-CoV-2 omicron variant after tixagevimab-cilgavimab treatmentArticle Published on 2022-11-012022-11-15 Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Abstract cilgavimab monoclonal mutations neutralizing monoclonal antibodies Omicron variant Resistance mutation SARS-CoV-2 Sequencing Tixagevimab Treatment [DOI] 10.1016/j.jinf.2022.07.014 PMC 바로가기
Hamsters Protected from SARS-CoV-2 Delta Variant Challenge after Two Doses of Adjuvanted SARS-CoV-2 Recombinant Spike Protein (S-2P) and One Dose of Beta S-2PArticle Published on 2022-11-012022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome Beta challenge coronavirus COVID-19 COVID-19 vaccine Delta dose Effectiveness hamster hamster challenge study highest live SARS-CoV-2 Live virus lung MVC-COV1901 neutralization Neutralizing antibody titer Omicron variant pathology prefusion PROTECT pseudovirus recombinant regimen S-2P SARS-CoV-2 SARS-CoV-2 delta SARS-CoV-2 vaccine spike Spike protein subunit Subunit vaccine suggested vaccination Vaccines variant variant of concern variants variants of concern virus Wuhan [DOI] 10.1093/infdis/jiac153 PMC 바로가기
Comparative study of the usefulness of risk score assessment in the early stages of COVID-19 affected pregnancies: Omicron variant versus previous variantsArticle Published on 2022-11-012022-11-16 Journal: The journal of obstetrics and gynaecology research [Category] SARS, 변종, 치료기술, [키워드] affected age Blood C-reactive protein Comparative Course COVID-19 D-dimer level Delta Deterioration disease disease onset early stage Epidemic evaluate examination findings Frequency group groups less no significant difference not significantly different omicron Omicron variant parameter Patient Platelet Pneumonia Pregnancy pregnant Prognosis risk risk scoring significantly lower two group utility variant variant of concern variants was increased worsening [DOI] 10.1111/jog.15387 PMC 바로가기
Simultaneous co-infection with Omicron (B.1.1.529) and Delta (21A/478K.V1) SARS-CoV-2 variants confirmed by whole genome sequencingArticle Published on 2022-11-012022-11-16 Journal: International Journal of Infectious Diseases [Category] SARS, 변종, [키워드] B.1.1.529 Co-infection COVID-19 Delta delta variant French omicron Omicron variant Patient reported SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Sequencing Simultaneous whole genome [DOI] 10.1016/j.ijid.2022.09.002 PMC 바로가기
Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2Article Published on 2022-10-312023-07-10 Journal: Viruses [Category] COVID19(2023년), [키워드] delta variant Norway Omicron variant SARS-CoV-2 Viral load [DOI] 10.3390/v14112420 PMC 바로가기
Decoding the effects of spike receptor binding domain mutations on antibody escape abilities of omicron variantsArticle Published on 2022-10-302022-11-15 Journal: Biochemical and Biophysical Research Communication [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] affinities antibodies antibody Antibody binding antibody escape appear approach approved binding affinity binding free energy cause Coverage COVID19 decrease Effect evaluate globe hotspot immune evasion immunogenic Immunogenic hotspot immunoinformatics K417N monoclonal antibody mutant Mutation mutations omicron Omicron variant Omicron variants Omicron variants. Point mutation RBD mutation RBD-specific antibody recent Receptor binding domain reduce reduction in REGN10987 residue selection pressure significantly single mutation the binding affinity therapeutic vaccination variants [DOI] 10.1016/j.bbrc.2022.08.050 PMC 바로가기
Accessible and Adaptable Multiplexed Real-Time PCR Approaches to Identify SARS-CoV-2 Variants of ConcernArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome approach collected concern coronavirus COVID-19 COVID-19 pandemic Critical cross-reactivity Delta delta variant detect different time points equipment exhibited FIVE genotyping identify Laboratory lack Limits of detection management melting curve analysis Molecular assay multiplex Multiplex PCR Mutation mutations nine omicron Omicron variant other coronaviruses PCR PCR assay performed platform positive sample Rapid rapid genotyping. Real-time PCR resource RNA SARS-CoV-2 SARS-CoV-2 VOCs selected sensitivity Sequencing signature specificity Spike protein Support Surveillance variant variants variants of concern VoC VOCs WGS [DOI] 10.1128/spectrum.03222-22 PMC 바로가기
Neutralizing SARS-CoV-2 Spike Antibodies against Omicron in Paired Samples after Two or Three Doses of mRNA VaccineArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] addition antibodies antibody Beta booster dose confounder COVID-19 death Delta demonstrated detect eliminated Hospitalization Immune escape mRNA mRNA vaccination mRNA vaccine neutralization neutralization activity Neutralizing neutralizing capacity Neutralizing titer omicron Omicron variant other variant protection provide reactive Sample SARS-CoV-2 SARS-CoV-2 antibody testing Seroprevalence Serum Neutralization significant increase significantly higher spike spike IgG tested the spike protein the vaccine unique utility Vaccine vaccine response variant variants of concern [DOI] 10.1128/spectrum.02046-22 PMC 바로가기