In silico validation of potent phytochemical orientin as inhibitor of SARS-CoV-2 spike and host cell receptor GRP78 bindingResearch Article Published on 2021-01-112022-10-31 Journal: Heliyon [Category] COVID-19, [키워드] In silico docking acute respiratory syndrome Anti-inflammation antinociceptive Antiviral binding contagious coronavirus COVID-19 docking domain drug Effect effective Effects GRP78 Health host cell receptor host receptor in silico inhibitor Interaction interfere MD simulation measure Molecular dynamics simulation Orientin outbreak overlapping pandemic phytochemical plant Research residue SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike glycoprotein Simulation spread to Still the disease therapeutic Treatment Vaccine vasodilatation Wuhan, China [DOI] 10.1016/j.heliyon.2021.e05923 PMC 바로가기 [Article Type] Research Article
The Strategy of Boosting the Immune System Under the COVID-19 PandemicVeterinary Science Published on 2021-01-082022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] addition cellular mechanisms claimed Coronavirus infection COVID-19 COVID-19 progression Critical Defense deficiencies detect disease drug Effect evaluate global pandemic immune response Immunity induce Infection Inflammation insulin Intervention marker Minerals Novel coronavirus nutraceutical nutraceuticals nutritional intervention outcome pandemic Pathogenesis Patient positive Prevent Probiotics raised recommendations Regulation required SARS-CoV-2 SARS—CoV-2 spread to Strategy System the patient viral infections viral replication vitamins WHO World Health Organization [DOI] 10.3389/fvets.2020.570748 PMC 바로가기 [Article Type] Veterinary Science
COVID-19 and its implications for obstetrics and gynecology practice in AfricaReview Published on 2021-01-072022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, [키워드] Africa African Care country COVID-19 Gynecology Health Health Service implication Implications morbidity Mortality obstetrics Practice reported routine spread to Virus Disease Wuhan, China [DOI] 10.11604/pamj.2021.38.15.25520 PMC 바로가기 [Article Type] Review
Predicting health behavior in response to the coronavirus disease (COVID-19): Worldwide survey results from early March 2020Research Article Published on 2021-01-072022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Analysis China collected complex interplay Compliance conducted coronavirus disease COVID-19 Critical death demographic characteristics demographic factor demographic variable effective emotional facilitate Health Health authority identify outbreak pandemic precursor predicted predictor predictors proximal Reactions regimen Regulation rising severity spread to susceptibility the disease understanding Vaccine variable variables Wuhan [DOI] 10.1371/journal.pone.0244534 PMC 바로가기 [Article Type] Research Article
Identification and molecular characterization of mutations in nucleocapsid phosphoprotein of SARS-CoV-2Biochemistry Published on 2021-01-042022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] alterations America analysed conducted country COVID-19 domain ENCODE envelope protein events function genomic RNA help hotspot identification identify include Infectious disease interact Interaction interfere intrinsically membrane protein molecular multiple mutation Mutation mutations N-protein nucleocapsid Nucleocapsid Phosphoprotein (N protein) oligomerization Protein RBD Region reported residue residues reveal RNA RNA genome SARS-CoV-2 SARS-CoV-2 genome sequence spike glycoprotein spread to stability structural protein United State USA Variation Wuhan, China [DOI] 10.7717/peerj.10666 PMC 바로가기 [Article Type] Biochemistry
SARS-CoV-2 -RNA persists longer in faecal sample as compared to nasal and throat swab samples of COVID-19 patients’; an observational studySARS-CoV-2 -RNA는 COVID-19 환자의 비강 및 인후 면봉 샘플과 비교하여 대변 샘플에서 더 오래 지속됩니다. 관찰 연구Article Published on 2021-01-012022-09-11 Journal: Indian journal of medical microbiology [Category] SARS, 치료기술, [키워드] clinical Clinical features clinical sample clinical samples COVID-19 patient COVID-19 positive patients discharged Faecal RNA persistence faece Faeces household contact household contacts hygiene infection control nasal nasal swab novel novel SARS-CoV-2 virus Perineal cleaning persist RNA route SARS CoV-2 SARS-CoV-2 SARS-CoV-2 virus serum spread to the disease throat swab Transmission Urine vaginal delivery [DOI] 10.1016/j.ijmmb.2020.10.012 PMC 바로가기 [Article Type] Article
Addressing Africa’s pandemic puzzle: Perspectives on COVID-19 transmission and mortality in sub-Saharan AfricaMini review Published on 2021-01-012022-10-05 Journal: International Journal of Infectious Diseases [Category] SARS, 유전자 메커니즘, [키워드] Africa African approach cause changes country COVID-19 COVID-19 case COVID-19 susceptibility COVID-19 transmission death Factor infecting Infectious disease Intervention median age Mortality outbreak outcome pandemic populations predicted Public health interventions rapid increase responsible resulting SARS-CoV-2 SARS-CoV-2 cases spread to sub-Saharan Africa virus [DOI] 10.1016/j.ijid.2020.09.1456 [Article Type] Mini review
Spectrum of neuroimaging findings in COVID-19Pictorial Review Published on 2021-01-012022-10-27 Journal: The British Journal of Radiology [Category] COVID-19, MERS, [키워드] change China Complication COVID-19 Critical Critically ill Encephalopathy feature Hemorrhagic hospitalized COVID-19 hospitalized patient hypertensive hypoxic include infections manifestation multiple sclerosis outbreak positive patient Spectrum spread to state stroke syndrome Venous thrombosis Virus Disease worldwide pandemic [DOI] 10.1259/bjr.20200812 PMC 바로가기 [Article Type] Pictorial Review
First COVID-19 case in Zambia – Comparative phylogenomic analyses of SARS-CoV-2 detected in African countries잠비아 최초의 COVID-19 사례 - 아프리카 국가에서 발견된 SARS-CoV-2의 비교 계통 분석Case Reports Published on 2021-01-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] activity African Analysis applied B.1 B.1.1 lineage caused China Community Comparative Contact tracing country COVID-19 COVID-19 case Diagnosis Disease surveillance Epidemic epidemic disease Europe Evolution of SARS-CoV-2 France genome sequence Health care Health care worker health care workers incidence of COVID-19 individual initial Lineage lineage B.1.1 MONITOR National Novel coronavirus novel coronavirus SARS-CoV-2 phylogenetic analyses predominant preparation resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 strains South Africa Spread spread to Surveillance sustained the patient Travel while Wuhan Wuhan, China Zambia [DOI] 10.1016/j.ijid.2020.09.1480 PMC 바로가기 [Article Type] Case Reports
Tocilizumab combined with favipiravir in the treatment of COVID-19: A multicenter trial in a small sample sizeCOVID-19 치료에서 토실리주맙과 파비피라비르 병용: 소규모 표본 크기의 다기관 시험Randomized Controlled Trial Published on 2021-01-012022-09-11 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] SARS, 임상, 진단, 치료법, 치료제, [키워드] 95 % CI Absorption addition assigned Blood routine clinical symptom Clinical symptoms Combination Combined therapy COVID-19 COVID-19 patient COVID-19 patients cumulative Deterioration drug Efficacy and safety elevated Favipiravir help IL-6 IMPROVE indicated inhibit interleukin interleukin-6 lung Lung CT Lung inflammation lung lesion Multicenter trial no significant difference Patient patients with COVID-19 Primary outcome pulmonary inflammation Randomly reported SARS-CoV-2 Serious Adverse Event Serious Adverse Events significant difference significantly significantly higher small sample size spread to the disease theory Tocilizumab Treatment treatment of COVID-19 with COVID-19 [DOI] 10.1016/j.biopha.2020.110825 PMC 바로가기 [Article Type] Randomized Controlled Trial