Interventions for treatment of COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING Project)Protocol Published on 2020-05-092022-10-28 Journal: Systematic Reviews [Category] COVID-19, MERS, SARS, [키워드] Admission aggregate data meta-analyses all age group all-cause mortality assessment caused clinical trial registry COVID-19 database development diagnosis of COVID-19 disease domains drug Effect effective evaluate events Evidence globe identify include intensive care Intervention invasive mechanical ventilation meta-analyses Mortality Network meta-analysis non-serious adverse Noninvasive ventilation outcome pandemic participant patient data pharmacological pharmacological interventions Placebo prevalent protocol Quality of life randomized clinical trial randomized clinical trials renal replacement therapy Research risk of bia secondary Serious Adverse Events standard care systematic review therapy threshold Treatment virus infection [DOI] 10.1186/s13643-020-01371-0 PMC 바로가기 [Article Type] Protocol
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19Original Article Published on 2020-03-182022-11-01 Journal: The New England Journal of Medicine [Category] COVID-19, MERS, SARS, [키워드] 1:1 95% CI 95% confidence interval addition adverse event adverse events Analysis assigned benefit breathing ambient air cause caused Chinese clinical Clinical improvement conducted creation defined detectable development discharge drug effective fraction Future Gastrointestinal hazard ratio help hospital Hospitalized laboratory-confirmed SARS-CoV-2 infection less Lopinavir–ritonavir Major median time modified intention-to-treat New Open-label oxygen oxygen saturation Patient percentage primary end point randomization Randomized Randomly receive Respiratory illness Result SARS-CoV-2 SARS-COV-2 infection Science Serious Adverse Event seven-category ordinal scale standard care technology Treatment Trial Viral RNA [DOI] 10.1056/NEJMoa2001282 PMC 바로가기 [Article Type] Original Article
Current Standards of Care and Long Term Outcomes for Thalassemia and Sickle Cell DiseaseArticle Published on 2017-12-312024-09-09 Journal: Adv Exp Med Biol [Category] 말라리아, [키워드] clinical care outcome Sickle cell disease standard care thalassaemia thalassemia PMC 바로가기