Computational design and modeling of nanobodies toward SARS-CoV-2 receptor binding domain
SARS-CoV-2 수용체 결합 도메인에 대한 나노바디의 컴퓨터 설계 및 모델링
Article
[키워드] ACE2
ACE2 binding site
acute respiratory syndrome
addition
angiotensin-converting enzyme 2
binding
binding affinity
binding domain
binding mechanism
caused
CDRs
complementarity-determining region
complex
computational protein design
Contact
coronavirus
coronavirus disease
COVID-19
docking
domain
effective
FIVE
free energy landscape
grafting
Health
host cell
host cells
include
Infection
information
inhibit
Interaction
mAb
mAbs
mechanism
MERS-CoV
monoclonal antibody
nanobody
Neutralizing
neutralizing nanobody
pandemic
predicted
Prevent
Protein
Protein docking
RBD
reported
residue
SARS-CoV
SARS-CoV-2
SARS-CoV-2 RBD
SARS-CoV-2 receptor
selected
sequence
Seven
specific neutralizing antibody
Spike protein
Spread
stability
Structure
structures
therapeutic drug
virus
virus infection
[DOI] 10.1111/cbdd.13847 PMC 바로가기 [Article Type] Article
[DOI] 10.1111/cbdd.13847 PMC 바로가기 [Article Type] Article