COVID-19 Life Events-Anxiety Inventory (C-19LAI): development, reliability, and validity study on Egyptian populationResearch Published on 2021-04-022022-10-29 Journal: Middle East Current Psychiatry [Category] COVID-19, [키워드] Anxiety applied Arabic correlated COVID 19 COVID-19 COVID-19 pandemic cross event inventory life Life events Life Events-Anxiety Inventory (C-19LAI) multiphasic pandemic reliability Result scale sensitivity significantly STAI subject supplementary material Validity [DOI] 10.1186/s43045-021-00101-z PMC 바로가기 [Article Type] Research
Practical approach to prevent COVID-19 infection at breast cancer screening유방암 검진 시 코로나19 감염 예방을 위한 실천적 접근Original Article Published on 2021-04-022022-09-01 Journal: Breast Cancer (Tokyo, Japan) [Category] MERS, SARS, 진단, [키워드] Adding addition aerosol Aerosols airflow applied approach benefit blower Breast cancer Cancer Cancer screening Care CFD Computational fluid dynamics conducted Contamination coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection discharged evaluated examiner exhalation experiment foundation Health Health care Health promotion infection control Laboratory Mobile Screening MMG bus services Novel coronavirus novel coronavirus disease open Patient Prevent prevention promotion proportion Result risk risk reduction room scanner Simulation supplementary material Ventilation [DOI] 10.1007/s12282-021-01235-y PMC 바로가기 [Article Type] Original Article
Novel mutations in NSP-1 and PLPro of SARS-CoV-2 NIB-1 genome mount for effective therapeuticsResearch Published on 2021-04-022022-10-30 Journal: Journal of Genetic Engineering & Biotechnology [Category] COVID-19, [키워드] acute respiratory syndrome Antiviral attenuated vaccine binding binding affinity circulating clinical samples computational tools conserved coronavirus coronavirus disease Coronavirus-2 COVID-19 damaged decrease develop effective Efficacy exhibited Genome genome sequence GRL0617 help inhibitor inhibitors Innate immunity ISG-15 knowledge less mutant Mutation mutations neutralized Non-synonymous mutation novel NSP-1 Papain-like protease prevalent protease Protein reduced reported residue Result SARS-CoV-2 supplementary material therapeutic Vaccine viral spread wild type [DOI] 10.1186/s43141-021-00152-z PMC 바로가기 [Article Type] Research
Virtualized clinical studies to assess the natural history and impact of gut microbiome modulation in non-hospitalized patients with mild to moderate COVID-19 a randomized, open-label, prospective study with a parallel group study evaluating the physiologic effects of KB109 on gut microbiota structure and function: a structured summary of a study protocol for a randomized controlled study입원하지 않은 경증에서 중등도의 COVID-19 환자에서 장내 미생물군유전체 조절의 자연사 및 영향을 평가하기 위한 가상화된 임상 연구 장내 미생물군 구조에 대한 KB109의 생리학적 효과를 평가하는 병렬 그룹 연구와 함께 무작위, 공개, 전향적 연구 및 기능: 무작위 대조 연구를 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-022022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 24 hours Ability absence addition adhere Affect age Ageusia allergy analysed Anosmia Anosmia/ageusia Antacid Antibiotics Antiviral assessment assigned Autoimmune disease Bariatric surgery baseline bilevel positive airway pressure Biomarker Biomarkers biomarkers of inflammation BiPAP Blinding blocker Blood blood sample Blood samples both groups bowel bowel resection breath Care care provider Cell change Chest chest tightness chills chronic lung disease cirrhosis clinical clinical study clinical trial Cold collected Community Comorbidity comparator Patients completion Compliance component computer Concomitant medication concomitant medications concurrent condition conducted contraindications coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 in patient COVID-19 symptom COVID-19 symptoms COVID-19 testing COVID-19-related symptom COVID-19-related symptoms COVID-19–related symptom COVID-19–related symptoms CPAP Cytokines D-dimer daily dose Day defined diarrhea dissemination drug duration of symptom Effect element eligible Enrollment evaluate evaluate the effect evaluated exacerbated exclusion criteria exploratory fatigue fatty Fatty acid feasible Female patients Fever fiber Follow-up follow-up period following group Gut gut microbiome gut microbiome composition gut microbiota headache Health Health care Health Care Utilization Health status healthcare Histamine history hospital Hospital admission Hospital admissions Hospitalization Hospitalized hypoxia Identifier IgM/IgG Immunity immunomodulatory immunosuppressive immunosuppressive therapy in both group include Infection Inflammation Inflammatory biomarker Inflammatory bowel disease information Informed consent inhibitors intake Interaction investigational agent irritable bowel syndrome KB109 Laboratory laboratory measures lactating library life Liver disease Lung disease magnitude malignancy management measure Measures medication medications Medicine metabolite Microbiome microbiota Mild mild to moderate Mild to moderate COVID-19 mild to moderate disease moderate Moderate COVID-19 moderate disease modulate modulation muscle pain nasal congestion neutralization assays not limited nucleic acid number objective Open-label opinion other compound other compounds outcome outcome measure Outpatient outpatients oxygen oxygen saturation Oxygen therapy Pain parallel group participant Participation Patient patient population Period Physical examination positive airway pressure Positive test Potential pre-symptomatic pregnant Primary outcome progression proportion proportions Prospective Study PROTECT protocol protocols proton pump provided pulse Pulse oximeter Quality of life Quantitative question randomisation randomised randomised controlled study randomization Randomized randomized controlled study receive recruitment reduction Registered reported response resting position risk risk of infection Sample size screened selected self-care sensitivities Sequencing serological serology shaking short-chain fatty acids Shortness of breath Sleep sleep apnea Smartphone sore throat specific biomarker specific biomarkers Spread SSC Standard Stool stratified Study design Study protocol study visit supplementary material Swab Symptom symptomatic patient Symptomatic patients Symptoms syndrome Tablet TEAEs Telemedicine telephone temperature the patient The United States therapy time Tolerability Treatment treatment-emergent adverse event undergo United States unlikely Viral Viral load water website worsening [DOI] 10.1186/s13063-021-05157-0 PMC 바로가기 [Article Type] Letter
Gene signature and immune cell profiling by high-dimensional, single-cell analysis in COVID-19 patients, presenting Low T3 syndrome and coexistent hematological malignanciesResearch Published on 2021-04-012022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, MERS, [키워드] acute phase addition Analysis analyzed approach CD3+ CD38 CD4+ CD79B CD8+ T cells change clinical disease Coagulation coexistent consecutive patients coronavirus disease (COVID-19) correlated correlation count COVID-19 COVID-19 patient COVID-19 patients Critical CyTOF cytokine Cytometry demonstrated Differentially expressed genes disease effector memory expressed expression First wave Gene expression profiling group Hematological malignancies Hematological malignancy Hospitalized Host immune response IFIT3 IL-6 Immune cell immune response indicate Inflammation intensive care unit involved IP-10 leukemia LIPI Low T3 syndrome marker mononuclear cell multiplex NanoString NLR NLRP3 outbreak Patient patients with COVID-19 PBMC performed Peripheral blood Pneumonia presenting radiologic reduced reduction reported Result Rome SARS-CoV-2 serum Serum level serum levels severe COVID-19 severity single-cell SOFA subtype supplementary material syndrome T lymphocytes target gene the disease thyroid function tissue damage TSS university [DOI] 10.1186/s12967-021-02805-6 PMC 바로가기 [Article Type] Research
The pilot, proof of concept REMOTE-COVID trial: remote monitoring use in suspected cases of COVID-19 (SARS-CoV 2)파일럿, 개념 증명 REMOTE-COVID 시험: COVID-19(SARS-CoV 2) 의심 사례에서 원격 모니터링 사용Research Article Published on 2021-04-012022-09-01 Journal: BMC Public Health [Category] MERS, SARS, 진단, [키워드] acceptability acting adverse event age applied changes in clinical Clinical deterioration clinical trial conducted COVID-19 COVID-19 symptom COVID-19 symptoms deaths demonstrated determine e parameters eligible evaluate exposure to extension feasibility general practitioner healthcare Healthcare professional healthcare professionals hospital hospitalisation hotel Identifier individual intervene London Mild MONITOR monitoring system Monitoring, ambulatory pandemic parameter Participants Patient Patient deterioration Public Health England quarantine reassurance Recognition reduced remote remote monitoring remote monitoring system Remote monitoring systems Remote sensing technology required respiratory rates Result resulting SARS-CoV 2 SARS-CoV-2 sensor supplementary material Symptom telephone contact temperature the mean threshold Trial Viral vital sign vital signs with COVID-19 [DOI] 10.1186/s12889-021-10660-9 PMC 바로가기 [Article Type] Research Article
Assessing critical gaps in COVID-19 testing capacity: the case of delayed results in EcuadorCOVID-19 테스트 용량의 심각한 격차 평가: 에콰도르에서 지연된 결과의 경우Research Article Published on 2021-04-012022-09-01 Journal: BMC Public Health [Category] MERS, SARS, 진단, [키워드] Assessing association average clinical care clinically collected contribute country COVID-19 COVID-19 cases COVID-19 testing Critical database death rate death rates Decision making Decision-making diagnostic diagnostic testing Diseases Ecuador Generalized linear model Health policy highest highlight individual inequality Infectious diseases information information management Laboratory limitation management Ministry of Health mitigate National physical processed processing reported resource Result RT-PCR testing Sample subsequent supplementary material Testing Vaccination strategies Vaccination strategy WHO’ [DOI] 10.1186/s12889-021-10715-x PMC 바로가기 [Article Type] Research Article
The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysisResearch Article Published on 2021-04-012022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval acute respiratory syndrome adjusted odds ratio Admission Admissions Antenatal association Cohort conducted confounding variables coronavirus COVID-19 COVID-19 disease demonstrated determine hospital Hypothesis iatrogenic increased risk infected with SARS-CoV-2 intensive care Intensive care units, neonatal Logistic regression analysis membrane morbidity mother multicentre multivariable analysis Neonatal Obstetric Occurrence outcome outcomes PCR positive pregnancies Pregnancy pregnant women Premature premature birth Premature rupture of membranes Preterm birth preterm delivery Prospective Study Research Result rupture SARS-CoV-2 SARS-COV-2 infection screened Spain statistically supplementary material tested women [DOI] 10.1186/s12884-021-03742-4 PMC 바로가기 [Article Type] Research Article
The relationship between SARS-COV-2 RNA positive duration and the risk of recurrent positiveResearch Article Published on 2021-03-312022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, SARS, [키워드] 95% CI adjusted analyses Analysis association Chinese COVID-19 COVID-19 patient discharge enrolled estimate evaluated female greater higher risk hospital hypertension increase in increased risk interactions Logistic regression management median age monocyte not significant participant Patient performed positive positive patients prevention Recurrent positive Result risk RNA SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA positive duration stratified supplementary material [DOI] 10.1186/s40249-021-00831-6 PMC 바로가기 [Article Type] Research Article
Among equity and dignity: an argument-based review of European ethical guidelines under COVID-19Research Article Published on 2021-03-312022-10-28 Journal: BMC Medical Ethics [Category] COVID-19, Fulltext, SARS, [키워드] adopted Allocation of Health Care Resources Analysis Care Clinical practice consequence COVID-19 COVID-19 outbreak COVID-19 pandemic criteria described distress equity ethical guideline Ethics European Health Human Dignity inclusion criteria knowledge management organization organized outbreak Patient produced Research resource Result supplementary material [DOI] 10.1186/s12910-021-00603-9 PMC 바로가기 [Article Type] Research Article