Low frequency of SARS-CoV2 infection in daycare centers during the reopening of school activities in the Southeast’s poor area of Brazil브라질 남동부 빈곤지역 등교 재개시 어린이집 SARS-CoV2 감염빈도 낮음Article Published on 2022-06-242022-09-11 Journal: Revista do Instituto de Medicina Tropical de São [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] activity age Asymptomatic average average age Brazil caused children collected conducted country death deaths Effectiveness female health authorities Health authority highest indicate lack low frequency Mortality nasopharynx occurred outbreak P.1 pandemic Participants positive Prevalence preventive measure purification rates of infection reopening return RNA extraction SARS-CoV-2 SARS-CoV2 SARS-CoV2 infection Secondary infection secondary infections Seven study population swab samples took place Transmission vaccination Vaccine variant Viral RNA was obtained [DOI] 10.1590/S1678-9946202264046 PMC 바로가기 [Article Type] Article
Nationwide Effectiveness of First and Second SARS-CoV2 Booster Vaccines During the Delta and Omicron Pandemic Waves in Hungary (HUN-VE 2 Study)헝가리의 델타 및 오미크론 대유행 기간 동안 1차 및 2차 SARS-CoV2 부스터 백신의 전국적인 효과(HUN-VE 2 연구)Observational Study Published on 2022-06-232022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] 4th vaccine 95% CI 95% confidence interval B.1.617.2 benefit booster booster dose booster vaccination Booster vaccine booster vaccines control group COVID-19 related mortality death Delta delta variant Delta variant (B.1.617.2) Delta wave demonstrated dose Effectiveness examined groups Hungary immunization immunized lower risk Mortality offered Older age omicron Omicron variant omicron variant (SARS-CoV-2) pandemic rate ratio risk SARS-COV-2 infection SARS-CoV-2 variants SARS-CoV2 SARS-CoV2 infection second significantly lower study population Vaccine vaccine effectiveness variant vulnerable population Wave [DOI] 10.3389/fimmu.2022.905585 PMC 바로가기 [Article Type] Observational Study
Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia급성 전골수구성 백혈병 환자의 항 SARS-CoV2 항체 매개 사이토카인 방출 증후군Case Reports Published on 2022-06-132022-09-12 Journal: BMC Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Activation Acute promyelocytic leukemia acute respiratory distress ADE Administered administration Admission advanced age adverse event Anemia antibody antibody treatment Antibody-dependent enhancement APL approach Bone marrow bruise Case report Clinical deterioration complex Coronavirus disease 2019 COVID-19 symptoms CRS Cytokine release syndrome death Diagnosis disease evidenced exacerbated Factor female hematological high risk highlight IL-10 IL-6 IL-8 immune immune activation immunization Infection Inpatients Laboratory leukemia leukemic life-threatening limit nasal passive immunization Patient positive potential risk radiological rapid increase reported SARS-CoV-2 SARS-CoV-2 RT-PCR SARS-CoV-2 testing SARS-CoV2 serum cytokine severe COVID-19 syndrome tested theoretical risk therapeutic therapy-related immunosuppression throat swab TNFα viral burden viral infection [DOI] 10.1186/s12879-022-07513-0 PMC 바로가기 [Article Type] Case Reports
A multiplex protein panel assay for severity prediction and outcome prognosis in patients with COVID-19: An observational multi-cohort studyResearch article Published on 2022-06-092022-10-05 Journal: EClinicalMedicine [Category] 바이오마커, 임상, [키워드] accelerate Accuracy agency APACHE II assessment Berlin Biomarker Biomarkers Charité clinical clinical disease progression Clinical outcome clinical risk clinical trials Cohort conducted Council COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 severity death Dexamethasone disease prognosis disease severity education ERC European finding foundation funding Germany hallmark Healthcare system healthy individuals help hospitalised introduced LC-MS/MS LLOQ machine learning median Medicine Mild Mobility moderate multiplex node observational study outcome Patient patient cohort patients with COVID-19 peptide peptides predicted Prognosis Prognostic value Protein proteomics quantification Registered registry Research resource SARS-CoV2 Science sensitivity severe COVID-19 severity Severity stratification SOFA Spectrometry Standard of care stratified Support supported survival System targeted proteomics the median the WHO Therapies Treatment Wellcome Trust [DOI] 10.1016/j.eclinm.2022.101495 [Article Type] Research article
Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics치료제로서의 최적 기능을 위한 Anti-SARS-CoV-2 단일클론항체 변형 전략 평가Article Published on 2022-06-032022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition alleviate antibody Antibody-dependent enhancement caused Cell circulating closure Combination coronavirus country COVID-19 infection COVID-19 infections COVID-19 pandemic death disease Economy Effect epitope Epitopes Health crisis Human human population humoral immune response in vitro infecting investigated LALA lockdown mAb mAbs modify monoclonal antibodies monoclonal antibody Mutation neutralize produced public health crisis public health measure public health measures reduce reported respiratory resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 SARS-CoV2 spike protein serum severe acute respiratory syndrome Coronavirus Spike protein Spread the antibody the disease the spike protein therapeutic option therapy These data Viral viral variant virus writing [DOI] 10.1371/journal.pone.0267796 PMC 바로가기 [Article Type] Article
Impact of Gestational COVID-19 on Neonatal Outcomes: Is Vertical Infection Possible?신생아 결과에 대한 임신성 COVID-19의 영향: 수직 감염이 가능합니까?Observational Study Published on 2022-06-012022-09-11 Journal: The Pediatric Infectious Disease Journal [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] acute infection analyzed Asymptomatic biological sample Blood breast milk Chain Reaction Characteristics Clinical characteristics Cohort conditions Cord blood Coronavirus-2 COVID-19 demographic demographic and clinical characteristics evaluated Follow-up hospital Impact in urine Infant Infants Infection life maternal blood meconium microbiologically Mild symptom mild symptoms MOST mother Nasopharyngeal swab nasopharyngeal swabs Neonatal Neonatal infection neonatal period Newborn no difference no differences Placenta polymerase chain reaction Pregnancy pregnant women remained reverse transcriptase reverse transcriptase-polymerase chain reaction SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral load SARS-CoV2 severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 Spanish susceptibility tested Transmission transmission of SARS-CoV-2 Urine vertical vertical transmission Viral load viral loads women [DOI] 10.1097/INF.0000000000003518 PMC 바로가기 [Article Type] Observational Study
Treatment of severe COVID-19 patients with either low- or high-volume of convalescent plasma versus standard of care: A multicenter Bayesian randomized open-label clinical trial (COOP-COVID-19-MCTI)Research article Published on 2022-06-012022-10-05 Journal: The Lancet Regional Health - Americas [Category] 임상, 치료법, [키워드] 95%CI acute lung injury allergic Analysis Antibody titer assigned Bayesian Bayesian framework benefit clinical benefits Clinical improvement clinical trial Combination conducted Controlled clinical trial convalescent plasma COVID-19 COVID-19 progression death Efficacy and safety eligible enrolled evaluate experimental group finding funding hospital hospitalized patient hospitals Innovation intention-to-treat population Interim interquartile range intravenous mean difference median titer Mild multicenter neutralizing antibody no evidence of Open-label Patient performed Plasma transfusion positive RT-PCR Prevent Primary outcome randomization Randomized randomized trial Randomly receive Registered SARS-CoV-2 SARS-CoV2 Science Severe case severe COVID-19 severe COVID-19 patient SOC Standard of care stratified Supportive treatment symptom onset technology the WHO Treatment Volume [DOI] 10.1016/j.lana.2022.100216 [Article Type] Research article
Severe COVID-19 is a T cell immune dysregulatory disorder triggered by SARS-CoV-2Article Published on 2022-06-012023-07-09 Journal: Expert review of clinical immunology [Category] COVID19(2023년), [키워드] COVID-19 immunodeficiency omicron plasma therapy SARS-CoV2 Vaccines [DOI] 10.1080/1744666X.2022.2074403
Lung vessel volume evaluated with CALIPER software is an independent predictor of mortality in COVID-19 patients: a multicentric retrospective analysisCALIPER 소프트웨어로 평가한 폐혈관 부피는 COVID-19 환자의 사망률에 대한 독립적인 예측인자입니다: 다심적 후향적 분석Article Published on 2022-06-012022-09-12 Journal: European Radiology [Category] MERS, 진단, [키워드] affected age Analysis analyzed CALIPER Care Chest CT Computed tomography Control COVID-19 COVID-19 patient COVID-19 patients demonstrated evaluated healthy control ILD increase independent informatics intensity Interstitial lung disease lung lung parenchyma material median Mortality multivariate Cox model outcome Patient performed required Retrospective analysis Retrospective study risk factor SARS-CoV2 severity statistically significant difference Structure tested Texture analysis. univariate Cox regression vessel Volume [DOI] 10.1007/s00330-021-08485-6 PMC 바로가기 [Article Type] Article
An insight into the mechanisms of COVID-19, SARS-CoV2 infection severity concerning β-cell survival and cardiovascular conditions in diabetic patientsReview Published on 2022-06-012023-07-08 Journal: Molecular and cellular biochemistry [Category] COVID19(2023년), [키워드] COVID-19 diabetes disease severity SARS-CoV2 Treatment β-Cell death. [DOI] 10.1007/s11010-022-04396-2 PMC 바로가기 [Article Type] Review