Outcome of SARS-CoV-2 variant breakthrough infection in fully immunized solid organ transplant recipients완전 면역된 고형장기 이식 환자에서 SARS-CoV-2 변이형 돌발성 감염 결과Article Published on 2022-01-012022-09-11 Journal: Journal of infection and public health [Category] SARS, 변종, [키워드] Admission Alpha variant Beta Beta variant BNT162b2 BNT162b2 mRNA Breakthrough infection breakthrough infections Case series case sery ChAdOx1 circulating COVID-19 vaccines delta variant died Efficacy Future immune response immunized intensive care nasal observation older patients one patient outcome oxygen Patient Pfizer-BioNTech Post-vaccine recipient recipients required risk SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 variant SARS-CoV-2 variants SARSCoV-2 SARSCoV-2 variant of concern Saudi Arabia severe pneumonia solid organ solid organ transplant Solid organ transplant recipients solid organ transplants supplemental oxygen Two patient two patients vaccination Vaccine variant ventilatory support were infected younger patients [DOI] 10.1016/j.jiph.2021.11.021 PMC 바로가기 [Article Type] Article
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study우려의 알파(B.1.1.7) 변종과 비교한 SARS-CoV-2 델타(B.1.617.2)에 대한 입원 및 응급 치료 출석 위험: 코호트 연구Comparative Study Published on 2022-01-012022-09-10 Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 변종, 치료기술, [키워드] adjust adjusted adjusted hazard ratio Admission age Alpha Alpha variant Analysis B.1.1.7 B.1.617.2 both groups Care Cohort cohort study Cox regression data set dataset death delta variant Department Deprivation Digital dominant Emergency Emergency Care England Ethnicity finding funding Generation greater health-care health-care service health-care services hospital Hospital admission immunisation Innovation International lead Lineage median age Medical Research Council Mortality Most patient Most patients National NHS outbreak outcomes Patient patients with COVID-19 Precision predominant Public Health England Relative risk residence Result risk SARS-CoV-2 delta SARS-CoV-2 variant second secondary Sequencing service severe disease severity Sex specimen Stratified Cox regression subgroups System Transmissibility Travel unvaccinated population unvaccinated populations vaccination Vaccination Status variant was done was used whole-genome sequencing [DOI] 10.1016/S1473-3099(21)00475-8 PMC 바로가기 [Article Type] Comparative Study
Genome sequencing of SARS-CoV-2 reveals the prevalence of variant B 1.1.7 in EgyptSARS-CoV-2의 게놈 시퀀싱은 이집트에서 변이 B 1.1.7의 유행을 보여줍니다Article Published on 2022-01-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome coronavirus Alpha Alpha variant authorization B 1.1.7 B.1.1.7 case fatality rates clade compatibility convalescent coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 Egypt eight Emergency expected feasibility Government Hospitalization hospitalizations majority measure Ministry of Health Monoclonal antibody treatments neutralization new SARS-CoV-2 new strain no effect outbreak Prevalence public health raised recorded respiratory reveal Sample SARS-CoV-2 SARS-CoV-2 B.1.1.7 Sequencing sera severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity shown strain susceptibility the SARS-CoV-2 transmission rate Treatment protocol Vaccine variant Viral Viral transmission [DOI] 10.1016/j.meegid.2021.105191 PMC 바로가기 [Article Type] Article
Neutralization assays for SARS-CoV-2: Implications for assessment of protective efficacy of COVID-19 vaccinesArticle Published on 2022-01-012022-11-15 Journal: The Indian journal of medical research [Category] SARS, 변종, 진단, [키워드] Alpha variant Analysis Beta Beta variant COVID-19 vaccine Delta delta variant described dose Efficacy Final fold drop fold reduction Gamma Gamma variant generate in vitro inclusion criteria Laboratory Live virus neutralization Neutralization assay Neutralizing activity omicron platform Protective pseudovirus recipients Sample size SARS-CoV-2 SARS-CoV-2 isolates SARS-CoV-2 variant searched selected serum strain the WHO titre Vaccine vaccinees Variability variant variants variants of concern Variation virus strain VOCs WHO [DOI] 10.4103/ijmr.ijmr_2544_21 PMC 바로가기
Number of public health nurses and COVID-19 incidence rate by variant type: an ecological study of 47 prefectures in Japan변종 유형별 공중보건 간호사 수 및 코로나19 발병률: 일본 47개 도도부현에 대한 생태학적 연구Article Published on 2022-01-012022-09-11 Journal: Environmental health and preventive medicine [Category] SARS, 변종, [키워드] 95% CI 95% confidence interval activity adjusted Alpha Alpha variant Analysis association Characteristics community health confirmed COVID-19 case covariates COVID-19 COVID-19 case COVID-19 cases COVID-19 incidence COVID-19 pandemic cumulative delta variant ecological Ecological studies effective estimating equation Government Health healthcare highest human resource IMPROVE incidence incidence rate Infectious disease Infectious diseases investigated Japan Local lowest multivariable number Nurse outcome performed Poisson regression model public health public health nurse Public health nurse. rate ratio reported resource resources Socioeconomic factor Socioeconomic Factors spread of COVID-19 stratified variant were used wild type [DOI] 10.1265/ehpm.22-00013 PMC 바로가기 [Article Type] Article
Environmental contamination of a quarantine hotel via SARS-CoV-2 positive travellersSARS-CoV-2 양성 여행자를 통한 격리 호텔의 환경 오염Article Published on 2021-12-292022-09-11 Journal: Journal of Travel Medicine [Category] Fulltext, SARS, 변종, [키워드] Alpha variant Beta Beta variant China Contamination COVID-19 International international travel Isolation positive quarantine SARS-CoV-2 Transmission VoC [DOI] 10.1093/jtm/taab148 PMC 바로가기 [Article Type] Article
The co-circulating transmission dynamics of SARS-CoV-2 Alpha and Eta variants in Nigeria: A retrospective modeling study of COVID-19나이지리아의 SARS-CoV-2 알파 및 에타 변이체의 동시 순환 전파 역학: COVID-19의 후향적 모델링 연구Research Theme 1: COVID-19 Pandemic Published on 2021-12-252022-09-10 Journal: Journal of Global Health [Category] MERS, SARS, 변종, [키워드] Alpha Alpha variant B.1.1.7 B.1.525 capture contributing to COVID-19 COVID-19 pandemic credible intervals Critical decrease disease disease control epidemic wave epidemiological Eta Evidence evidence of Health care Health care system health care systems interval mathematical mathematical model measure Mutation Nigeria outbreak outcome prevalent public health Reproduction number reproduction numbers Result retrospective SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 variant SARS-CoV-2 variants strain Strains suggested surveillance data threat Transmission Transmission dynamics variant variants wild type [DOI] 10.7189/jogh.11.05028 PMC 바로가기 [Article Type] Research Theme 1: COVID-19 Pandemic
Evolution of enhanced innate immune evasion by SARS-CoV-2SARS-CoV-2에 의한 강화된 타고난 면역 회피의 진화Article Published on 2021-12-232022-09-10 Journal: Nature [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료법, [키워드] Activation adaptation airway airway epithelial cell airway epithelial cells Alpha Alpha variant antagonists assays association B.1.1.7 changes in characterization coding region contribute Delta Duration of infection effective effort ENhance epithelial cells expression first-wave Human human-to-human transmission immune responses increase increase in innate immune innate immune response innate immune responses Interaction isolate isolates lead likelihood MAVS mitochondrial Mutation nucleocapsid protein observation omicron ORF6 Orf9b Phosphoproteomics Phosphorylation Protein protein level protein levels Proteins proteomics regulated regulatory region Replication required RNA RNA sequencing SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Spike protein suppress suppresse suppressed Systems biology the spike protein Transmission upregulation variant variants variants of concern Viral viral adaptation viral replication [DOI] 10.1038/s41586-021-04352-y PMC 바로가기 [Article Type] Article
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta베타가 아닌 알파의 SARS-CoV-2 변종에 대한 향상된 적합성Comparative Study Published on 2021-12-222022-09-10 Journal: Nature [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] ACE2 airway Alpha Alpha variant angiotensin assessment B.1.1.7 B.1.351 Beta Beta variant COVID-19 pandemic cultures driver driving enhanced epithelial experiment Experimental models of disease expressing ferret ferrets fitness greater hamster hamsters high viral replication highlight human ACE2 human Angiotensin-converting enzyme in vitro in vivo mechanism mice nasal overcome progenitor receptor Replication respiratory SARS-CoV-2 SARS-CoV-2 variant similar replication kinetics Spike protein Substitution substitutions Support the spike protein Transmission upper respiratory tract variant variants of concern Viral viral infection virus VoC VOCs [DOI] 10.1038/s41586-021-04342-0 PMC 바로가기 [Article Type] Comparative Study
Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer임신한 흰꼬리사슴에서 조상 SARS-CoV-2 및 그 알파 변이체의 감염 및 전파Coronaviruses Published on 2021-12-212022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] addition Alpha Alpha variant Alpha VOC B.1.1.7 B.1.1.7 isolate cervid circulating Co-infection competition Contact coronavirus deer demonstrated determine direct contact evidence of examined fetus Genome global pandemic Host human population human populations in silico in viral in vitro study indicated Infection intermediate hosts investigated Lineage nasal natural infection Next-generation sequencing oral cavities outbreak Pregnancy pregnant recent reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 isolates SARS-like coronavirus Sequencing shown susceptibility susceptible tissue tissues Transmission transmission of SARS-CoV-2 variant variety Viral virus VoC was used white-tailed deer widespread [DOI] 10.1080/22221751.2021.2012528 PMC 바로가기 [Article Type] Coronaviruses