associations – Page 19 – Communicable Diseases Research

Molecular Characterization of Three Canine Models of Human Rare Bone Diseases: Caffey, van den Ende-Gupta, and Raine Syndromes

인간 희귀 뼈 질환의 세 가지 개 모델의 분자 특성: 카페, 반 덴 엔데 굽타 및 레인 증후군

Research Article

Published on 2016-05-172022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

Network-based analysis of comorbidities risk during an infection: SARS and HIV case studies

Research Article

Published on 2014-10-242022-10-27
Journal: BMC Bioinformatics [Category] Coronavirus, Fulltext, MERS,

[키워드] Affect affected Analysis ANXA3 approach association associations Breast cancer Cancer chronic heart failure clinical information Comorbidities infections Comorbidity correlation data-driven diabete diabetes Differential gene expression disease Disease associations Diseases dysregulated Gene Expression Genes GHITM GNS HBA1 heart failure HIST1H1C HIV HIV infection HIV-1 immune responsiveness immunological diseases impacts implicated increase induce infective Inflammatory diseases Inflammatory response kidney disorder knowledge measure mechanism medical condition MERS virus MERS-CoV morbidity and mortality neurodegenerative disorders neurological NFKBIA notable OMIM other diseases pathology pathway Pathways Patient PPI quantified Quantitative quantitative framework RASA3 relative Result risk SARS SARS-CoV significantly statistically supplementary material susceptibility TFRC Type
[DOI] 10.1186/1471-2105-15-333 PMC 바로가기 [Article Type] Research Article

A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach

새로운 MMP12 유전자좌는 게놈 전체 발병 연령 정보 접근 방식을 사용하여 대동맥 죽상경화성 뇌졸중과 연관됩니다

Research Article

Published on 2014-07-312022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] (atherosclerosis) affected affection age analyses Analysis approach arteries Artery association associations Atherosclerosis atherosclerotic carotid carotid artery chromosome chromosome 11 Conditioning controls covariate demonstrated detect disease disease risk European evaluate Evidence evidence of examined explain Fold change fraction genetic association genetic associations genetic component Genetic predisposition Genetic variant Genome-wide association studies global healthcare GWAS heterogeneity identify IMPROVE increased risk independent information Informed investigated ischaemic stroke large artery lead loci locus Meta-analysis MMP12 mRNA expression novel novel association novel associations overexpressed performed phenotype phenotypic plaque plaques power prevalence rate prevalence rates Regression regression analysis Replication risk significantly small vessel SNP association SNP associations stroke subtype Subtypes the disease variant variants was performed
[DOI] 10.1371/journal.pgen.1004469 PMC 바로가기 [Article Type] Research Article

The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition Groove

HLA 클래스 I 항원 인식 그루브와 관련된 중국 비인두암의 주요 유전적 결정인자

Research Article

Published on 2012-11-292022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] allele allele frequencies alleles Amino acid Analysis analyzed antigens association associations Author binding Cancer carcinoma carried China Chinese chromosome chromosome 6 class Cohort concert dependent on detect detected determinant disease driven by EBV epithelial Epstein-Barr virus examined facilitated GABBR1 Gene gene region genetic influence Genome-wide association study Groove Guangdong Guangxi GWAS HCG9 help High-resolution HLA HLA alleles HLA class I HLA class I gene HLA region HLA-A HLA-A and -B HLA-B HLA-F incidence independent Infection influences influences on Interaction involved large cohort Linkage disequilibrium malignancy molecular motif multivariate Nasopharyngeal carcinoma NPC nucleotide operative OR2H1 over peptide performed physically principal Recognition recognize Region regression analysis replicate Replication resolved risk second sequence SNP SNPs statistical study participant the major histocompatibility the strongest variant variants virus infection
[DOI] 10.1371/journal.pgen.1003103 PMC 바로가기 [Article Type] Research Article

Abernethy malformation: a case report

Case Report

Published on 2012-05-292023-08-29
Journal: BMC Pediatrics [Category] E형 간염,

[키워드] Abernethy malformation associations complications India Ultra-sonography
[DOI] 10.1186/1471-2431-12-57 PMC 바로가기 [Article Type] Case Report

A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation

사르데냐인의 염증 표지자 수준에 대한 게놈 전체의 연관성 스캔은 복잡한 조절을 뒷받침하는 연관성을 보여줍니다

Research Article

Published on 2012-01-262022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] ABO gene AIRE APOC-I approach association associations Author autosomal C-reactive protein CADM3 CCR2 Cohort common disease complex conducted CR1 CRP CRP gene damaged cells DARC detect different different diseases Effects erythrocyte sedimentation erythrocyte sedimentation rate ESR Evidence Factor found functional Gene genetic determinant genetic determinants Genetic variant genetic variants genome-wide association scan Genome-wide association scans genome-wide significant genotyped GWAS HBB Health help High-sensitivity C-reactive protein highlight HNF1A hsCRP ICOSLG identifying IL-6 IL-6R gene ImmunoChip implicated IMPROVE included independent individual individuals Inflammation inflammation erythrocyte sedimentation rate Inflammatory biomarker interleukin interleukin-6 knowledge large cohort led to Level loci MCP-1 mechanism MetaboChip custom arrays molecular mechanism molecular mechanisms monocyte monocyte chemotactic protein-1 novel organism performed power pro-inflammatory molecule pro-inflammatory molecules Protective Protein provided QTLs Quantitative quantitative traits receptor Regulation replicated robust rs113459440 rs11829037 rs1205 rs12075 rs12567990 rs17141006 rs225918 rs3026968 rs3093077 rs3845624 rs4129267 rs4420638 rs4910472 rs657152 Sardinia Sardinian sedimentation rate selected SNP SPPL3 TMEM57 UCN119B UNC119B variant X chromosome SNP
[DOI] 10.1371/journal.pgen.1002480 PMC 바로가기 [Article Type] Research Article

Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis Pneumonia

AIDS에 대한 케모카인 수용체 유전자의 외음성 변이의 역할: 폐포자충과의 CCRL2 F167Y 연관성

Research Article

Published on 2011-10-272022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] 95% CI accelerated addition Affect AIDS Amino acid Analysis association associations Atypical Author CCR2 CCR3 CCR5 CCR8 CCRL2 Cell Chemokine receptor chromosome Cluster cohorts conditions CX3CR1 defined dendritic cell disease Disease progression DNA Effect exonic FIVE functional variant functional variants Gene Genes Genetic genetic association Genetic variation genotyped HIV-1 HIV-1 infection host cells Human immune regulation in addition to indicated Inflammation involved key factor lung majority natural history Non-synonymous outcome Pathogenesis Pneumonia progression role Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs surface protein survival survival analysis tested variant Variation
[DOI] 10.1371/journal.pgen.1002328 PMC 바로가기 [Article Type] Research Article