Self-Collection of Saliva Specimens as a Suitable Alternative to Nasopharyngeal Swabs for the Diagnosis of SARS-CoV-2 by RT-qPCRArticle Published on 2021-01-152022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age chronic conditions Clinical diagnosis Concordance Contagion COVID-19 cycle threshold diagnosis of SARS-CoV-2 equipment evaluate gold standard Infection involved lysis buffer nasopharyngeal nasopharyngeal sample Nasopharyngeal swab Patient patients processed professional Prospective Study risk RT-qPCR Saliva SARS-CoV-2 SARS-COV-2 infection significantly higher specificity Symptoms utility virus detection were used [DOI] 10.3390/jcm10020299 PMC 바로가기 [Article Type] Article
Effectiveness of In-Hospital Cholecalciferol Use on Clinical Outcomes in Comorbid COVID-19 Patients: A Hypothesis-Generating StudyArticle Published on 2021-01-142022-10-31 Journal: Nutrients [Category] COVID-19, [키워드] administer Administered amplified Analysis benefit cholecalciferol cholecalciferol treatment clinical Clinical characteristics Clinical outcome clinical trial comorbid disease comorbid diseases comorbid patient Comorbidity COVID-19 COVID-19 patients D-dimer level death diagnosis of SARS-CoV-2 died Effect elevated Endpoint explain follow-up period High-dose Hospitalized ICU In-hospital information intensive care Logistic regression analysis Mortality offer oral cholecalciferol outcome over Patient positive predictive power Propensity score receiver operating characteristic receiving Retrospective study significantly smoking transfer transferred treated Treatment Vitamin D vitamin D levels was recorded with COVID-19 [DOI] 10.3390/nu13010219 PMC 바로가기 [Article Type] Article
Impact of SARS-CoV-2 pandemic among health care workers in a secondary teaching hospital in Spain스페인의 중등 교육 병원에서 의료 종사자들 사이에 SARS-CoV-2 대유행의 영향Research Article Published on 2021-01-142022-09-10 Journal: PLoS ONE [Category] MERS, 치료기술, [키워드] age appearance assigned carried category compatible symptom compatible symptoms continuous surveillance COVID-19 COVID-19 pandemic cross-sectional cumulative diagnosis of SARS-CoV-2 doctor group HCW Health Health care worker Health personnel healthcare Healthcare system Healthcare systems healthcare worker Healthcare workers highest hospital identify IgG Impact incidence increased risk individual Infection medical departments medical service medical services medical staff molecular occupational occupational health organizations Patient positive presenting symptom presenting symptoms Prevalence recruited risk rRT-PCR SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 pandemic serological service Spain Surveillance Symptoms Viral virus women [DOI] 10.1371/journal.pone.0245001 PMC 바로가기 [Article Type] Research Article
Head-to-Head Comparison of Rapid and Automated Antigen Detection Tests for the Diagnosis of SARS-CoV-2 InfectionArticle Published on 2021-01-132022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] aligned antigen testing asymptomatic subject automated automated assay CDC contagious contagiousness COVID-19 detection diagnosis of SARS-CoV-2 faster FIVE Healgen identify Infection less manual assay nasopharyngeal sample PanBio patients ranged Rapid Roche RT-PCR RT-PCR positive patient SARS-CoV-2 SARS-CoV-2 RNA sensitivity specificity symptomatic patient Test tested Viral load viral loads [DOI] 10.3390/jcm10020265 PMC 바로가기 [Article Type] Article
Treatment of COVID-19 pneumonia with glucocorticoids (CORTIVID): a structured summary of a study protocol for a randomised controlled trial글루코코르티코이드(CORTIVID)를 사용한 COVID-19 폐렴의 치료: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-112022-09-10 Journal: Trials [Category] 임상, 치료기술, [키워드] absolute difference active cancer Admission age allergy ambient approved arterial blood Barcelona baseline biochemical Blinding Block randomisation block size Blood Breastfeeding C-reactive protein C-reactive protein (CRP candidate clinical Clinical outcome clinical outcomes clinical trial contraindication Control control group Controlled trial COVID-19 COVID-19 admission COVID-19 pneumonia criteria death decrease defined detect Deterioration Device diabete Diabetes Mellitus diagnosis of SARS-CoV-2 discretion dissemination drug drug treatment early treatment Effectiveness element elevated eligible emergency room ethics committee EudraCT exclusion criteria expected explained ferritin Follow-up followed by following glucocorticoid Glucocorticoids groups hospital Hospital admission hypertension ICU Identifier IL-6 immunosuppressants IMPROVE inclusion criteria independent Infection inflammatory biomarkers Informed consent intensive care intensive care unit interleukin interleukin-6 Intervention intervention group intravenous intravenous infusion Laboratory Loading dose Lopinavir Lopinavir/ritonavir maintenance dose management manic manic disorder mechanical ventilation Medical devices Medicine Medicines Methylprednisolone Nasopharyngeal swab nasopharyngeal swabs number objective outcome outcome assessor outcome assessors Outpatient oxygen oxygen saturation PaO parallel-group partial pressure Partial pressure of oxygen participant Patient patient age patients patients with COVID-19 Pharmacy Placebo Pneumonia polymerase chain Potential Pregnancy primary endpoint Primary outcome procalcitonin proportion protocol Psychiatric Psychological psychotic pulse Pulses Quadruple blind radiological random randomisation randomised randomised controlled trial randomizeR receive recommendation recruit recruitment Registered Remdesivir required researcher reverse transcriptase Reverse transcriptase polymerase chain reaction Ritonavir RT-PCR Sample size SARS-CoV-2 SARS-CoV-2 pneumonia sequence Spain Spanish sputum Standard of care status stratified study outcomes Study protocol supplementary material Symptom Tablet the patient therapy title total sample size transcriptase Treatment treatment failure Trial Trial registration two group two groups two-tailed type I type II error uncontrolled hypertension unit university Version website with COVID-19 [DOI] 10.1186/s13063-020-04999-4 PMC 바로가기 [Article Type] Letter
Covert cases of Severe Acute Respiratory Syndrome Coronavirus 2: An obscure but present danger in regions endemic for Dengue and Chikungunya viruses중증 급성 호흡기 증후군 코로나바이러스 2의 은밀한 사례: 뎅기열 및 치쿤구니야 바이러스 풍토병 지역의 모호하지만 존재하는 위험Research Article Published on 2021-01-062022-09-10 Journal: PLoS ONE [Category] 진단, 치료기술, [키워드] acute infection acute infections antibody Brazil Chikungunya Clinical features clinical symptom Clinical symptoms collected conducted contributed coronavirus covert COVID-19 COVID-19 diagnosis Dengue dengue virus Diagnosis diagnosis of SARS-CoV-2 Endemic expected feature finding IgG immunoassay Immunoglobulin Immunoglobulin G infections knowledge Microparticle outbreak Patient patients positive Presence Prevalence prevalent Region regions respiratory robust Sample size SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 nucleoprotein serum sample serum samples tested Viral viral infection virus [DOI] 10.1371/journal.pone.0244937 PMC 바로가기 [Article Type] Research Article
Different Respiratory Samples for COVID-19 Detection by Standard and Direct Quantitative RT-PCR: A Literature ReviewReview Article Published on 2021-01-012022-10-30 Journal: Iranian Journal of Pharmaceutical Research : IJPR [Category] COVID-19, [키워드] acute respiratory syndrome approach collected comparable Contact coronavirus Coronavirus disease 2019 costly cough COVID-19 decrease detection diagnose diagnosis of SARS-CoV-2 diagnostic Diagnostic method Direct HCW HCWs healthcare worker heat inactivation increased risk Infection less literature Lower respiratory tract medium Nasopharyngeal swab NPs oropharyngeal swab Patient patients performed physical proteinase protocol purification Quantitative respiratory respiratory tract samples review RNA extraction RT-qPCR RT-qPCR assay Saliva saliva sample Sample SARS-CoV-2 specimen sputum Standard time-consuming Transmission Transport Treatment upper Viral load Viral RNA [DOI] 10.22037/ijpr.2021.115458.15383 PMC 바로가기 [Article Type] Review Article
Update of the recommendations of the Sociedade Portuguesa de Cuidados Intensivos and the Infection and Sepsis Group for the approach to COVID-19 in Intensive Care MedicineSpecial Article Published on 2021-01-012022-10-29 Journal: Revista Brasileira de Terapia Intensiva [Category] COVID-19, SARS, [키워드] Admission African anticoagulation antivirals approach conducted Coronavirus infections country COVID-19 COVID-19/diagnosis COVID-19/therapy criteria Critically ill patient DelPhi diagnosis of SARS-CoV-2 East Evidence Evolution group had no Health Health Service immunomodulator Infection knowledge management Medicine methodology National pathology PICO Practice guidelines as topic professional Protective question recommendation recommendations Respiratory Support SARS-CoV-2 Support systematic review therapy Timor Treatment with COVID-19 [DOI] 10.5935/0103-507X.0103-507X-rbti-20210080 PMC 바로가기 [Article Type] Special Article
The Main Molecular and Serological Methods for Diagnosing COVID-19: An Overview Based on the LiteratureCOVID-19 진단을 위한 주요 분자 및 혈청학적 방법: 문헌을 기반으로 한 개요Review Published on 2020-12-292022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed approach caused Characteristics coronavirus coronavirus disease COVID-19 COVID-19 pandemic Critical Decision making diagnose Diagnosis diagnosis of SARS-CoV-2 diagnostic Diagnostic method diagnostic methods diagnostic test diagnostic tests Disease progression Diseases effective Factors Human Infection Infectious diseases initial lack literature molecular testing nucleic acid onset of symptoms organized point-of-care progression protocol respiratory SARS-CoV-2 SARS-COV-2 infection serological Serological tests serology testing severe acute respiratory syndrome Coronavirus shown simplicity the disease therapeutic Vaccines virus [DOI] 10.3390/v13010040 PMC 바로가기 [Article Type] Review
Visual Detection of SARS-CoV-2 RNA by Conventional PCR-Induced Generation of DNAzyme SensorMolecular Biosciences Published on 2020-12-232022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] catalytic Colorimetric assay comparable Conventional correlation COVID-19 COVID-19 cases COVID-19 transmission Ct-value curtail detection develop diagnose diagnosis of SARS-CoV-2 diagnostic DNAZyme Generation gold standard imperative labor-intensive molecular Nasopharyngeal swab PCR polymerase chain Real-time PCR real-time-PCR RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Sensitivity and specificity sensor shown Spearman specimen unmet need Visual [DOI] 10.3389/fmolb.2020.586254 PMC 바로가기 [Article Type] Molecular Biosciences