Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohortResearch Article Published on 2021-11-232022-10-31 Journal: eLife [Category] COVID-19, MERS, SARS, [키워드] Admission Analysis Care case fatality ratio clinician Cohort Commonwealth COVID-19 development discharge disease severity Epidemic Foreign foundation had no HDU high dependency unit hospital Hospital admission Hospital stay hospitalisation hospitalised hospitalised patient Human ICU improvement Infectious disease intensive care International limitation lowest manuscript Melinda Gate office outcome measure pandemic Patient Probability provided resource SARS-CoV-2 Study design supported Survivors symptom onset time trials variable Variation viruses with COVID-19 [DOI] 10.7554/eLife.70970 PMC 바로가기 [Article Type] Research Article
Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation ProtocolObservational Study Published on 2021-11-212022-10-04 Journal: Thorax [Category] COVID19(2023년), Fulltext, MERS, SARS, 임상, [키워드] 4C Deterioration 4C Mortality 95% CI age C-statistic calibration calibration-in-the-large CCP-UK clinical clinical decision Clinical deterioration COVID-19 Critical care data extraction death defined demonstrated Deterioration died England Final Follow-up hospital Hospital admissions hospitalised In-hospital ISARIC main outcome measure management Mortality National Health Service nine Observational cohort study pandemic participant patients Performance metrics predict prognostic model Prospective recalibration recruited regions remained respiratory Result risk score risk stratification second wave subgroups Treatment validation cohort validation cohorts ventilatory support WHO with COVID-19 [DOI] 10.1136/thoraxjnl-2021-217629 PMC 바로가기 [Article Type] Observational Study
Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, PortugalResearch Article Published on 2021-11-192022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] age Analysis clinical Cluster Clusters collected cough COVID-19 Dyspnoea Effect Fever First wave group headache higher odd hospitalisation hospitalised increasing age Infection likelihood multivariable myalgia occur pandemic Patient Portugal positive Positive test predict predictor Presence recent finding regions Respiratory disease respiratory symptom Sex surveillance data Symptom Symptoms tested was performed [DOI] 10.1371/journal.pone.0260249 PMC 바로가기 [Article Type] Research Article
Retrospective cohort study to evaluate medication use in patients hospitalised with COVID-19 in Scotland: protocol for a national observational study스코틀랜드에서 COVID-19로 입원 한 환자의 약물 사용을 평가하기위한 후 향적 코호트 연구 : 국가 관찰 연구를위한 프로토콜Pharmacology and Therapeutics Published on 2021-11-192022-09-10 Journal: BMJ Open [Category] Fulltext, MERS, SARS, 치료제, [키워드] Administered Analysis approval board caused changes in choice clinical pharmacology clinical trials cohort study Committee COVID-19 death described description Dexamethasone dissemination Dose escalation drug East estimation Ethics evaluate Evidence example exploratory exposure to finding FIVE hospital hospitalisation hospitalisations hospitalised In-hospital Infection information knowledge medication Medicine Medicines National outcomes Panel Patient peer-reviewed platform Prevent Primary outcome privacy protocol Public real-world data receiving reduced risk Release Remdesivir Repurposed drug Research Ethics retrospective cohort study routine clinical practice SARS-COV-2 infection Scottish service severe COVID-19 South Surveillance switching Therapeutics Tocilizumab treated Treatment Vaccine website with COVID-19 [DOI] 10.1136/bmjopen-2021-054861 PMC 바로가기 [Article Type] Pharmacology and Therapeutics
CATALYST trial protocol: a multicentre, open-label, phase II, multiarm trial for an early and accelerated evaluation of the potential treatments for COVID-19 in hospitalised adults촉매 시험 프로토콜 : 입원 성인의 COVID-19에 대한 잠재적 치료의 초기 및 가속 평가를위한 멀티 센터, 오픈 라벨, 2 단계, 다중 암 시험.Intensive Care Published on 2021-11-112022-09-10 Journal: BMJ Open [Category] Fulltext, MERS, SARS, 임상, [키워드] accelerated Admission adult intensive & critical care Analysis approval approved Biomarker C reactive protein candidate drugs chest X-ray clinical clinical picture COVID-19 CRP CT scan death dissemination dysregulated immune response East Efficacy eligible Ethics ethics committee Evidence evidence of hospital discharge hospitalised Hospitalised patients identify immunomodulation IMPROVE improvement include Infectious diseases inflammatory monocyte inflammatory monocytes initial International Macrophage macrophages MHRA Monocytes multicentre National Open-label outcome Patient peer-reviewed platform Platform trial Pneumonia positive Potential treatment primary outcome measure proinflammatory protocol public health registration numbers Research Ethics reverse transcription PCR rheumatology SARS-COV-2 infection SARS-CoV-2 pneumonia scale secondary Secondary outcomes severe SARS the WHO therapeutic strategy thoracic medicine Treatment Trial trials usual care with COVID-19 [DOI] 10.1136/bmjopen-2021-050202 PMC 바로가기 [Article Type] Intensive Care
Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid and antibody tests up to 22 August 2020Research Published on 2021-11-112022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval Accuracy Antibody test antibody tests Area Asymptomatic clinical specificity confidence interval Continuous country COVID-19 COVID-19 pandemic defined diagnostic eight European heterogeneity hospitalised management Meta-analysis Mild nucleic acid nucleic acid test nucleic acid tests point-of-care point-of-care test point-of-care tests pooling Population Result SARS-CoV-2 SARS-CoV-2 nucleic acid sensitivity Sensitivity and specificity significantly higher specificity thresholds union [DOI] 10.2807/1560-7917.ES.2021.26.45.2001675 PMC 바로가기 [Article Type] Research
Development of a predictive prognostic rule for early assessment of COVID-19 patients in primary care settingsResearch article Published on 2021-11-012022-10-05 Journal: Atencion Primaria [Category] SARS, 유전자 메커니즘, [키워드] analyses cardiac disease clinical Clinical course Comorbidities Comorbidity Confusion correlation Course COVID-19 COVID-19 patient Critical Deceased demographics development diabete Dyspnoea evaluated external validation Follow-up headache hospitalised hypertension increased risk increasing age laboratory-confirmed Logistic regression Male sex men Mortality myalgia myalgias objective Older outcome participant Patient patients Predictive Predictive model primary care Prognosis prognostic Prognostic factor reduced risk relationship remained renal Result retrospective cohort risk ROC setting significantly Spain survivor Symptom symptomatic patient Symptoms variables [DOI] 10.1016/j.aprim.2021.102118 [Article Type] Research article
Clinical outcomes in patients infected with different SARS-CoV-2 variants at one hospital during three phases of the COVID-19 epidemic in Marseille, France프랑스 마르세유의 COVID-19 전염병의 3단계 동안 한 병원에서 다양한 SARS-CoV-2 변종에 감염된 환자의 임상 결과Article Published on 2021-11-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 유전자 메커니즘, [키워드] 501Y age and gender age and gender distribution Alpha B.1.1.7 B.1.177 B.1.351 Beta Chronic diseases circulating clade clinical Clinical characteristics Clinical severity clinical symptom Clinical symptoms cohort study conducted COVID-19 COVID-19 epidemic death demographics distribution evaluate France hospital hospitalisation hospitalised infected with SARS-CoV-2 Infection large cohort Lineage Marseille Mutation Nextstrain nine obese Occurrence outcome outcomes P.1 pangolin Patient Prevalence retrospective cohort study SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severity transfer Transmissibility variant variants [DOI] 10.1016/j.meegid.2021.105092 PMC 바로가기 [Article Type] Article
What are the factors that affect post COVID 1st month’s continuing symptoms?포스트 COVID 1 개월째 계속되는 증상에 영향을 주는 요인은 무엇입니까?Article Published on 2021-11-012022-09-11 Journal: International journal of clinical practice [Category] SARS, 치료기술, [키워드] accounted Admission Affect age applied Characteristics Chest chronic disease Chronic diseases comorbid disease comorbid diseases cough COVID COVID-19 CRP D dimer D-dimer diagnosed with COVID-19 diarrhoea disease Dual therapy Dyspnoea examined Factor had more hospital Hospital admission hospital information system hospitalised Hospitalised patients individual information Information System initial Laboratory myalgia Older outpatient clinic pathology Patient patient information Platelet Pneumonia reported Research smoking Symptom treated Treatment was collected was determined weakness [DOI] 10.1111/ijcp.14778 PMC 바로가기 [Article Type] Article
Olfactory dysfunction and coronavirus disease 2019 severity: a prospective cohort studyObservational Study Published on 2021-11-012022-10-05 Journal: The Journal of laryngology and otology [Category] SARS, 임상, [키워드] age Ageusia Anosmia association Chest computed tomography Computed tomography coronavirus coronavirus disease Course COVID-19 disease severity dysfunction dysgeusia evaluate evaluated female hospitalised impairment male olfactory dysfunction Patient patients Prevalence prognostic prospective cohort study prospective observational cohort Questionnaires radiological finding severity Smell statistically significant were assessed [DOI] 10.1017/S0022215121002425 PMC 바로가기 [Article Type] Observational Study