The characteristics and outcomes of critically Ill patients with COVID-19 who received systemic thrombolysis for presumed pulmonary embolism: an observational studyObservational Study Published on 2021-11-012022-10-05 Journal: Journal of Thrombosis and Thrombolysis [Category] 임상, [키워드] age angiography Autopsy Care Characteristics clinical suspicion conducted Coronavirus disease 2019 COVID-19 Critically ill Critically ill patient dead Deep venous thrombosis defined demonstrated discharge discharged discharged home disease DVT Evidence extracorporeal membrane oxygenation Hemostasis hospital hospitalized COVID-19 patient hypoxia Ill lung transplant male New York outcome overall mortality Patient patients patients with COVID-19 performed Prevalence pulmonary Pulmonary embolism rehabilitation facility respiratory respiratory insufficiency retrospective cohort study Shock survived Thrombus tissue plasminogen activator transferred utility venous thromboembolic Ventilation ventricular with COVID-19 worsening [DOI] 10.1007/s11239-021-02477-5 PMC 바로가기 [Article Type] Observational Study
An integrative multiomics analysis identifies putative causal genes for COVID-19 severity통합 멀티오믹스 분석으로 COVID-19 중증도에 대한 추정 인과 유전자 식별Article Published on 2021-11-012022-09-11 Journal: Genetics in medicine : official journal of the Ame [Category] SARS, 신약개발, 유전자 메커니즘, 치료제, [키워드] Analysis applied association Blood CCR2 complementary controls COVID COVID-19 COVID-19 HGI COVID-19 Host Genetics Initiative COVID-19 phenotype COVID-19 severity Critical eight evaluated FIVE Gene Expression Genes genomic genomic loci hospitalized COVID-19 patient identify IFNAR2 initiative loci lung tissue multiomics analysis NAPSA NSF OAS3 public health reduce SACM1L SARS Coronavirus SARS coronavirus 2 second target WNT3 XCR1 [DOI] 10.1038/s41436-021-01243-5 PMC 바로가기 [Article Type] Article
Assessment of antiphospholipid antibodies and calprotectin as biomarkers for discriminating mild from severe COVID-19경증에서 중증 COVID-19를 구별하기 위한 바이오마커로서의 항인지질 항체 및 칼프로텍틴의 평가Article Published on 2021-11-012022-09-11 Journal: Journal of Clinical Laboratory Analysis [Category] MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome antibodies antibody anticardiolipin antibodies anticardiolipin antibody antiphospholipid antibodies assessment association Biomarker C-reactive protein C-reactive protein (CRP calprotectin CD4 clinically coronavirus coronavirus disease correlation COVID-19 COVID-19 patient COVID-19 patients CRP CRP level CRP levels detectable Detection limit elevated ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated ferritin groups healthy control healthy controls help highest Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients IgM immunoassay IMPROVE Inflammatory laboratory parameter lymphocyte Lymphocyte count management Mild moderate multiplex negative correlation neutrophil Neutrophil-to-lymphocyte ratio no significant differences not differ outcome oxygenation status parameter pathway peak levels Prevalence procalcitonin proportion respiratory distress Respiratory distress syndrome sera severe COVID-19 severe group severity significant differences significantly significantly higher syndrome T cells two group two groups were measured [DOI] 10.1002/jcla.24004 PMC 바로가기 [Article Type] Article
Neurological symptoms of COVID-19 infection; a cross-sectional study on hospitalized COVID-19 patients in IranObservational Study Published on 2021-11-012022-10-04 Journal: Clinical neurology and neurosurgery [Category] 임상, [키워드] analyzed article auditory Characteristics clinical manifestation clinical manifestations Complication Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients cross-sectional demographic Dizziness Epidemiology female headache hospitalized COVID-19 patient hospitalized COVID-19 patients Hypogeusia increasing age Infection Infectious disease intensity Iran less male manifestation memory neurological neurological manifestation neurological manifestations Neurological symptom older patient paralysis patients Prevalence prevalent problem problems Seizure Seizures study population Symptom Tehran the disease treatment protocols variety [DOI] 10.1016/j.clineuro.2021.106985 PMC 바로가기 [Article Type] Observational Study
Sources and clinical significance of aspartate aminotransferase increases in COVID-19Research article Published on 2021-11-012022-10-05 Journal: Clinica chimica acta; international journal of cli [Category] SARS, 바이오마커, [키워드] abnormality Admission alanine aminotransferase alkaline phosphatase ALT Aspartate aminotransferase assays association AST Biomarker C-reactive protein (CRP coefficient confidence interval correlation COVID-19 death Effect Elevation evaluated explained hepatocellular hepatocellular injury Hospitalization hospitalized COVID-19 patient identify increase increases in independent Injury intensive care lactate dehydrogenase Liver injury mechanism mortality risk multifactorial Multiorgan outcomes patients performed predict Result SARS-CoV-2 Source systemic inflammation tissue tissue damage was increased [DOI] 10.1016/j.cca.2021.08.012 [Article Type] Research article
Special report of the RSNA COVID-19 task force: systematic review of outcomes associated with COVID-19 neuroimaging findings in hospitalized patientsRSNA COVID-19 태스크포스 특별 보고서: 입원 환자의 COVID-19 신경영상 소견과 관련된 결과에 대한 체계적인 검토Systematic Review Published on 2021-11-012022-09-12 Journal: The British Journal of Radiology [Category] 진단, [키워드] Acuity Acute disseminated encephalomyelitis adult COVID-19 patients advance age all-cause mortality Analysis articles COVID-19 COVID-19 patient demographics Disseminated encephalomyelitis element feature followed by hemorrhage high mortality rate highest hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients ICH intracranial hemorrhage Ischemic Stroke leptomeningeal leukoencephalopathy literature review Mortality Necrosis Neurological symptom Neurological symptoms outcome outcomes Patient performed Prognostic marker reported Specific stroke systematic review unique were recorded with COVID-19 [DOI] 10.1259/bjr.20210149 PMC 바로가기 [Article Type] Systematic Review
Plasma zinc status and hyperinflammatory syndrome in hospitalized COVID-19 patients: An observational studyObservational Study Published on 2021-11-012022-10-05 Journal: International immunopharmacology [Category] SARS, 임상, [키워드] 95% CI acute respiratory distress antiviral response association Biomarker cHIS. Clinical outcome Cohort Complication Concentration conducted control group correlated COVID-19 COVID-19 patient CRS cytokine releasing syndrome deficiency diagnosed with COVID-19 early stage eligible patient Hospital stay hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients Hyperinflammatory syndrome Infection Inflammation interquartile range IQR majority median median age morbidity Mortality Non-COVID-19 outcome outcomes Patient PCR-confirmed plasma zinc concentration Prevalence Prognostic marker retrospective risk robust SARS-CoV-2 severe SARS-CoV-2 significantly single-center Support syndrome tested the disease university hospital Zinc [DOI] 10.1016/j.intimp.2021.108163 PMC 바로가기 [Article Type] Observational Study
Special report of the RSNA COVID-19 task force: systematic review of outcomes associated with COVID-19 neuroimaging findings in hospitalized patientsSystematic Review Published on 2021-11-012022-10-27 Journal: The British Journal of Radiology [Category] COVID-19, [키워드] adult COVID-19 patients advance age all-cause mortality Analysis articles COVID-19 COVID-19 patient demographics element feature hemorrhage high mortality rate highest hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient ICH Ischemic Stroke leptomeningeal leukoencephalopathy literature review Mortality Necrosis Neurological symptom outcome outcomes Patient performed Prognostic marker reported Specific stroke systematic review unique were recorded with COVID-19 [DOI] 10.1259/bjr.20210149 PMC 바로가기 [Article Type] Systematic Review
Elevated cytokines and chemokines in peripheral blood of patients with SARS-CoV-2 pneumonia treated with high-titer convalescent plasma고역가 회복기 혈장으로 치료한 SARS-CoV-2 폐렴 환자의 말초혈액 내 사이토카인 및 케모카인 상승Research Article Published on 2021-10-292022-09-12 Journal: PLoS Pathogens [Category] MERS, SARS, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome addition administration Blood caused chemokine chemokines Clinical course clinical trial Cohort Concentration conducted contribute convalescent convalescent plasma Convalescent plasma therapy correlated Course COVID-19 COVID-19 pneumonia CRP cytokine Cytokine storm syndrome Cytokines Day Deterioration Disease progression Donor donors Efficacy elevated Elevation elevations evaluate fatality foundation healthy controls Hospitalization Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients IIa immune immune activation immune response IMPROVE increase in Inflammatory Inflammatory cytokines infusion institution Lung pathology mechanical ventilation MIP-1α MIP-1β Neutralizing antibodies neutralizing antibody Neutralizing titer observation outcomes pandemic Patient patients patients hospitalized patients with SARS-CoV-2 Peripheral blood phase plasma plasma sample plasma samples Pneumonia Potential biomarker potential biomarkers receive recipient recipients respiratory distress Respiratory distress syndrome resulting SARS-CoV-2 coronavirus SARS-COV-2 infection SARS-CoV-2 virus significant difference syndrome the cytokine storm the disease the patient the SARS-CoV-2 virus the timing track transfer treat treated Treatment unique virus while with COVID-19 [DOI] 10.1371/journal.ppat.1010025 PMC 바로가기 [Article Type] Research Article
Elevated Anti-SARS-CoV-2 Antibodies and IL-6, IL-8, MIP-1β, Early Predictors of Severe COVID-19Article Published on 2021-10-292022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute COVID-19 acute infection anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies association baseline Concentration COVID-19 COVID-19 patient COVID-19 severity criteria Cytokines cytokines IL-6 Diagnosis disease eight hospitalized COVID-19 patient Host ICU IFN-γ IgA IgG IgG antibodies IgM IL-1β IL-6 IL-8 immune intensive care Laboratory male median age MIP-1α MIP-1β MOST outcome persistence predictor Proinflammatory cytokine SARS-CoV-2 SARS-CoV-2 RNA severe COVID-19 severe COVID-19 disease Symptom Viral load were measured [DOI] 10.3390/microorganisms9112259 PMC 바로가기 [Article Type] Article