Post-Extubation Stridor Complicating COVID-19-Associated Acute Respiratory Distress Syndrome: A Case SeriesInternal Medicine Published on 2020-09-162022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome [ards] acute respiratory syndrome Affect airway extubation Analysis analyzed ARDS Case series case sery close monitoring common coronavirus Corticosteroid COVID-19 COVID-19 patient critical care patient Extubation failure female female gender incidence include Infection Intubated intubation majority mechanical ventilation morbidity and mortality nine Older age Patient predict Prone ventilation Prophylactic reducing respiratory respiratory complication risk factor SARS-CoV-2 Sery stridor susceptible syndrome the patient was performed while [DOI] 10.7759/cureus.10492 PMC 바로가기 [Article Type] Internal Medicine
A quadruple blind, randomised controlled trial of gargling agents in reducing intraoral viral load among hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-09-142022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] administration age antiviral therapy approved asked assumption blind blinded carried Chemical Chemotherapy clinical clinical trial COVID COVID-19 COVID-19 patient COVID-19 positive patients Cytokine analysis cytokine profile determine dissemination edentulous Effectiveness element eligibility assessment excluded expected explained female FIVE Flow gargles Glasgow coma score group hospitalised hydrogen hypertonic identify IFN-γ IL-10 IL-2 IL-4 IL-6 Immunological test Inc. inclusion criteria Intervention Intubated Karachi Laboratory laboratory-confirmed lesion male Mild moderate disease mucosal nasal Nasal lavage number objective outcome parallel group participant Patient PCR test positive controls Primary outcome product protocol provided Purposive sampling quantitative PCR Radiotherapy randomised randomised controlled trial real time reducing reduction in Registered reported Research Research question salivary Sample size sealed Standard status study group Study protocol subject Symptoms the patient TNF-α treated Trial unit university university hospital Viral load website [DOI] 10.1186/s13063-020-04634-2 PMC 바로가기 [Article Type] Letter
Time to adapt in the pandemic era: a prospective randomized non –inferiority study comparing time to intubate with and without the barrier box대유행 시대에 적응할 시간: 장벽 상자가 있는 경우와 없는 경우 삽관하는 시간을 비교한 전향적 무작위 비열등성 연구Research Article Published on 2020-09-142022-08-09 Journal: BMC Anesthesiology [Category] 임상, [키워드] 95% CI aerosol aerosol spread Aerosols Airway management in COVID patients airway management practices airway manipulation anesthesiologist anesthesiologists bag-mask ventilation Barrier box barrier boxe barrier boxes both groups clinically comparable confirmation COVID-19 disease defined determine Device disease elective surgeries end-tidal Endpoint enrolled full PPE’ full PPE’s glidescope group Hypothesis in both groups include Intubated intubation less limit loss of twitche loss of twitches lowest oxygen saturation Mean TTI modify Nerve stimulator non-inferiority controlled trial non-inferiority margin normal airway exam null hypothesis number of attempt oxygen oxygen saturation pandemic parameter Patient performed peripheral nerve peripheral nerve stimulator primary measured endpoint raise Randomized Randomly Registered rescue breaths Result secondary Secondary endpoints significant delay spread of COVID-19 study group t-test the mean the study group time time to intubate unpaired two-sample single-sided t-test Usage was used well-trained providers [DOI] 10.1186/s12871-020-01149-w PMC 바로가기 [Article Type] Research Article
Coronavirus Disease 2019-Related Acute Ischemic Stroke: A Case ReportInternal Medicine Published on 2020-09-082022-10-31 Journal: Cureus [Category] COVID-19, [키워드] absence absence of risk factors Aspirin Blood cerebrovascular accident cerebrovascular accidents Chest Comorbidities complications Coronavirus disease 2019 cough COVID-19 COVID-19 pandemic crepitation CRP D-dimer diffusion diverse presentation evaluated ferritin Fever Glasgow coma scale humans hypercoagulability intensity Intervention Intubated Ischemic Ischemic Stroke Leukocytosis lower limb lung male Measures morbidity and mortality Most patient MRI neurological signs Patient patient with COVID-19 PCR performed polymerase chain positive predominant Protein raised reduce report respiratory symptoms risk factor Shortness of breath stroke the patient tomography transthoracic echocardiography TSH virus vitamin B12 weakness with COVID-19 worldwide pandemic zone [DOI] 10.7759/cureus.10310 PMC 바로가기 [Article Type] Internal Medicine
Lung ultrasound score in establishing the timing of intubation in COVID-19 interstitial pneumonia: A preliminary retrospective observational studyResearch Article Published on 2020-09-032022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] 28-day mortality acute respiratory syndrome addition BMI changes in Characteristics condition coronavirus coronavirus disease COVID-19 Critical Critically ill patient died different time point effective evaluate female patient HFNC ICU in both groups individual intensive care interstitial interstitial pneumonia Intubated intubated patient intubation lung male material mechanical ventilation mechanically ventilated nasal nine NIV Non-intubated non-intubated patient Noninvasive ventilation oxygenation index PaO Patient patient groups per day Pneumonia respiratory rate Result retrospective SARS-CoV-2 SARS-CoV-2 pneumonia Seven severity significantly significantly higher SOFA the patient the timing treated two group two groups was performed worsened [DOI] 10.1371/journal.pone.0238679 PMC 바로가기 [Article Type] Research Article
Clinical Significance of Timing of Intubation in Critically Ill Patients with COVID-19: A Multi-Center Retrospective StudyArticle Published on 2020-09-022022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome Adjusted analysis adult COVID-19 patient ARDS Characteristics clinical Coronavirus 2019 Course COVID-19 COVID-19 patient criteria Critically ill Critically ill patient died Follow-up group groups help hospital ICU Ill In-hospital In-hospital death in-hospital mortality in-hospital mortality rate intensive care intensive care units Intubated intubation investigated mechanical ventilation Medical resources Mortality multicenter Non-intubated not significantly different Patient patients treated Prognosis Respiratory failure Result retrospective risk Significance significant difference subgroup analysis survival syndrome was done [DOI] 10.3390/jcm9092847 PMC 바로가기 [Article Type] Article
Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, FranceExpedited Published on 2020-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] acute respiratory syndrome clinical conducted coronavirus coronavirus 2 coronavirus disease COVID-19 description Diagnosis France Hospitalization Hospitalized ICU ICUs identify intensive care unit Intubated Laboratory Lymphocyte count management median Median BMI MERS obstetric unit oxygen Paris Patient patients Pregnancy pregnant women respiratory respiratory infections Retrospective study risk SARS SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 viruses women zoonoses [DOI] 10.3201/eid2609.202144 PMC 바로가기 [Article Type] Expedited
Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patientsOriginal Article Published on 2020-09-012022-10-31 Journal: Endocrine [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Analysis association clinical factor coronavirus coronavirus disease COVID-19 COVID-19 patients Cox model Cox proportional hazard Critically ill Critically ill patient defined enrolled evaluate evaluated hazard ratio identify Infectivity intensive care intensive care unit Intubated intubated COVID-19 patient Lower respiratory tract LTA multivariate Cox model Nasopharyngeal swab negative RT-PCR negative test negativity onset of symptom Patient polymerase chain prolonged viral shedding Prospective Study reliability Result risk factor RT-PCR SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 viral shedding tracheal aspirate treated type 2 diabete Type 2 diabetes mellitus viral clearance Viral RNA shedding viral shedding [DOI] 10.1007/s12020-020-02465-4 PMC 바로가기 [Article Type] Original Article
Case Report: Canakinumab for the Treatment of a Patient With COVID-19 Acute Respiratory Distress SyndromeImmunology Published on 2020-08-252022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory distress syndrome Adaptive immune response bacterial superinfection canakinumab CD56 Cell compassionate use condition correlated COVID-19 cytokine cytokine levels Cytokine release syndrome Cytokine storm died expressing high risk hospital Hospitalization IL-1 IL-1β IL-6 IL-6 level immune cells Infection interleukin-6 Intubated Lung inflammation Lymphocyte count male monoclonal antibody Multiorgan natural killer NK cell Patient presenting reduced renal rescued respiratory SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity severe cases significantly subset syndrome Treatment with COVID-19 [DOI] 10.3389/fimmu.2020.01942 PMC 바로가기 [Article Type] Immunology
Tocilizumab and steroid treatment in patients with COVID-19 pneumonia코로나19 폐렴 환자에서 토실리주맙과 스테로이드 치료Research Article Published on 2020-08-202022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] 95%CI adjusted age analyses anti-inflammatory treatment Comorbidities Comorbidity controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia Cox regression analysis darunavir death defined determine difference early treatment Efficacy Endpoint endpoints Evidence failure group hazard hazard ratio Hospital admission Hydroxychloroquine immune response IMPROVE intravenously Intubated intubation IQR lead male median median age Methylprednisolone non-intubated patient non-intubated patients not intubated outcome overall survival PaO Patient patients with COVID-19 Pneumonia primary endpoint Propensity score Ratio Respiratory failure Result Ritonavir Severe COVID-19 pneumonia single-center study Standard of care steroid steroid treatment Steroids subcutaneously survival Tocilizumab treated patient Treatment treatment with tocilizumab with COVID-19 [DOI] 10.1371/journal.pone.0237831 PMC 바로가기 [Article Type] Research Article