Pooled SARS-CoV-2 antigen tests in asymptomatic children and their caregivers: Screening for SARS-CoV-2 in a pediatric emergency department무증상 아동 및 보호자를 대상으로 한 SARS-CoV-2 항원 통합 검사: 소아 응급실에서 SARS-CoV-2 선별 검사Article Published on 2021-10-012022-09-11 Journal: American journal of infection control [Category] SARS, 치료기술, [키워드] Admission Asymptomatic Chain Reaction Child children comparable contagious COVID-19 Critical Ct values effective evaluated extraction buffer False negative hospital Hospital infection identify individual individuals infectious Lateral Lateral flow test medium Mid-turbinate. nasopharyngeal swabs Oropharyngeal Outbreaks P-value PCR PCR swab PCR testing pediatric performed polymerase chain polymerase chain reaction Prevent Result SARS-CoV-2 SARS-CoV-2 antigen Screening Sensitivity and specificity significantly single-center study study period Swab swabbing Turbinate Universal was performed were used [DOI] 10.1016/j.ajic.2021.07.009 PMC 바로가기 [Article Type] Article
Feasibility analysis on the construction of a web solution for hydrometeorological forecasting considering water body management and indicators for the SARS-COV-2 pandemicResearch Article Published on 2021-10-012022-10-28 Journal: AI Perspectives [Category] COVID-19, [키워드] Analysis artificial artificial intelligence assist Brazil Brazilian caused coronavirus COVID-19 COVID-19 pandemic COVID19 develop Diseases effective feasibility Forecasting generate global pandemic greater highlight Hydrometeorological forecast Impact IMPROVE intelligence lack less management MATOPIBA medium methodology Model MONITOR number of infected pandemic Predictive proliferation recipient reduced regions Research resource resources risk SARS-CoV-2 SARS-CoV-2 (COVID-19) strongly related treated virus water body Water resources weather WRF-Hydro [DOI] 10.1186/s42467-021-00011-0 PMC 바로가기 [Article Type] Research Article
Antibody Response to SARS-CoV-2 is Associated with Long-term Clinical Outcome in Patients with COVID-19: a Longitudinal StudySARS-CoV-2에 대한 항체 반응은 COVID-19 환자의 장기 임상 결과와 관련이 있습니다: 종단 연구Article Published on 2021-10-012022-09-12 Journal: Journal of Clinical Immunology [Category] MERS, SARS, 진단, [키워드] anti-SARS-CoV-2 antibody antibody Antibody Response association Blood characterized clinical conducted COVID-19 COVID-19 patient COVID-19 symptom defined demonstrated died event female female gender Health highest hospital Hospital stay Hospitalization Host immune response identify long-COVID longitudinal male median median age medium nasopharyngeal sample NPs occur outcome Patient patients patients hospitalized patients with COVID-19 positive predictor proportion Prospective questionnaire readmission Reinfection reported required response RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RT-PCR Sequencing serological severity Sex Symptom Symptoms viral replication Viral RNA shedding viral shedding Virological waned was performed WHO severity score [DOI] 10.1007/s10875-021-01083-7 PMC 바로가기 [Article Type] Article
Impact of a binary triage system and structural reorganization of emergency department on health care workers exposed to suspected COVID-19 patients—a single-centre analysisOriginal Research Published on 2021-09-232022-10-30 Journal: International Journal of Emergency Medicine [Category] COVID-19, [키워드] analysed Analysis conducted COVID-19 COVID-19 pandemic COVID-19 patient cross-sectional Department effective Effectiveness Emergency Emergency department structure facilitated Fever HCW HCWs Health care worker high risk Impact implementation Infection involved medium Patient patients reducing reduction in reported respiratory symptom Result risk risk of COVID-19 severity supported triage system [DOI] 10.1186/s12245-021-00384-3 PMC 바로가기 [Article Type] Original Research
Molecular evolutionary characteristics of SARS‐CoV‐2 emerging in the United StatesResearch Article Published on 2021-09-202022-10-04 Journal: Journal of medical virology [Category] SARS, 변종, 진단, [키워드] addition Amino acid beta coronavirus bioinformatics Bioinformatics analysis calculate Characteristics coding decrease Evolution Genome Health highly pathogenic Hypothesis medium molecular molecular evolution Mutation nonsynonymous mutation nucleotide Positive selection RNA viruses S gene S protein SARS‐CoV‐2 SARS‐CoV‐2 sequence Seven Spike protein statistically significant Surveillance the United State The United States virus virus variants was used were used whole genome whole genome sequence [DOI] 10.1002/jmv.27331 PMC 바로가기 [Article Type] Research Article
Discrepancies in Infectivity of Flavivirus and SARS-CoV-2 Clinical Samples: An Improved Assay for Infectious Virus Shedding and Viremia Assessment플라비바이러스와 SARS-CoV-2 임상 샘플의 감염력 불일치: 감염성 바이러스 배출 및 바이러스혈증 평가를 위한 개선된 분석Article Published on 2021-09-182022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition alternative Antibody titers assessment Avicel Cellulose clinical clinical sample clinical samples coronavirus COVID-19 culture medium Dengue evaluated flavivirus Improved infectious particles Infectivity infectivity assessment Laboratory MCC medium methylcellulose microcrystalline microcrystalline cellulose Neutralizing antibody titer neutralizing antibody titers nucleic acid nucleic acid amplification nucleic acid amplification tests overlay medium Particle plaque Plaque assay plaques respiratory SARS-CoV-2 SARS-CoV-2 strains sensitivity severe acute respiratory syndrome Coronavirus shedding significantly time-consuming Viremia virus virus infectivity virus strains virus titer virus titers Virus titration was performed was used while [DOI] 10.3390/ijerph18189845 PMC 바로가기 [Article Type] Article
Single and Combinative Impacts of Healthy Eating Behavior and Physical Activity on COVID-19-like Symptoms among Outpatients: A Multi-Hospital and Health Center SurveyObservational Study Published on 2021-09-182022-10-04 Journal: Nutrients [Category] SARS, 임상, [키워드] activity approach association Behavior boost center conducted contribute COVID-19-like symptoms cross-sectional Data collection eating effective fish fruits Health healthy healthy eating score immune function Impact IMPROVE Interaction International likelihood logistic regression models medium nine non-pharmacological outpatients pandemic physical activity Physical inactivity physically questionnaire Sociodemographic characteristics survey Symptom tested the healthy vegetables Vietnam [DOI] 10.3390/nu13093258 PMC 바로가기 [Article Type] Observational Study
Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic targetProlyl 이성질 효소 PIN1은 SARS-COV-2 증식에서 필수적인 역할을하며, 이는 새로운 치료 표적으로서의 가능성을 나타낸다.Article Published on 2021-09-172022-09-10 Journal: Scientific Reports [Category] SARS, 유전자 메커니즘, 진단, [키워드] activate Acute promyelocytic leukemia acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 added addition APL ATRA cells cellular coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CPE Culture culture medium Cytopathic effect drug Drug development expression global pandemic Infectious diseases inhibit inhibitor inhibitory effect leukemia medium molecular mechanism mRNA mRNA synthesis N protein novel Novel coronavirus novel coronavirus disease PIN1 potential therapeutic agent potential therapeutic agents proliferation Promyelocytic leukemia protein synthesis receptor reduced respiratory retinoic acid SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus siRNA suppressed Target identification therapeutic agents therapeutic target Transcription treat Viral [DOI] 10.1038/s41598-021-97972-3 PMC 바로가기 [Article Type] Article
Endothelial Cell Activation by SARS-CoV-2 Spike S1 Protein: A Crosstalk between Endothelium and Innate Immune CellsArticle Published on 2021-09-142022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] “cytokine storm” activated Activation addressed adhesion molecules alteration amplify cell activation chemokine chemokines Coagulopathy Combination conditioned contributing to COVID-19 Crosstalk CXCL10/IP-10 Cytokines decrease endothelial activation Endothelial cell endothelial cells Endothelial dysfunction Endothelium Evidence expression human lung human monocyte-derived macrophage hyperinflammatory state ICAM-1 impairment increased expression Infection Inflammatory response Innate Macrophage macrophages MDM mechanism medium multi-organ failure occur Pathogenesis pro-inflammatory mediator pro-inflammatory mediators Protein prothrombotic state released S1 protein SARS-CoV-2 severe COVID-19 spike spike S1 protein THBD the disease the S1 protein the SARS-CoV-2 the spike protein tissue Vascular vascular homeostasis VCAM-1 [DOI] 10.3390/biomedicines9091220 PMC 바로가기 [Article Type] Article
Factors Associated With Longitudinal Psychological and Physiological Stress in Health Care Workers During the COVID-19 Pandemic: Observational Study Using Apple Watch DataObservational Study Published on 2021-09-132022-10-04 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] A significant reduction age Analysis app Apple Watch autonomic baseline changes in Characteristics collected COVID-19 COVID-19 case COVID-19 diagnosis COVID-19 pandemic determine Effect emotion emotional enrolled Factor feature follow-up period HCW HCWs Health care worker heart rate heart rate variability highest hospital HRV identify increased risk individual longitudinal marker medium mental health Multivariate analysis nervous system nervous system function New York New York City objective Observational optimism pandemic participant Perceived stress physiological physiological consequence Physiology Protective Psychological Psychological distress Psychology Quality of life reduced risk Resilience Result risk significantly Stress Stressor subject Support survey Variability Warrior wearable device worker [DOI] 10.2196/31295 PMC 바로가기 [Article Type] Observational Study