Roche – Page 19 – Communicable Diseases Research

Quantitative Measurement of Anti-SARS-CoV-2 Antibodies: Analytical and Clinical Evaluation

Anti-SARS-CoV-2 항체의 정량적 측정: 분석 및 임상 평가

Article

Published on 2021-03-192022-09-11
Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술, 치료제,

Comparative effects of viral-transport-medium heat inactivation upon downstream SARS-CoV-2 detection in patient samples

환자 샘플에서 다운스트림 SARS-CoV-2 검출에 대한 바이러스 수송 매체 열 비활성화의 비교 효과

Comparative Study

Published on 2021-03-182022-09-10
Journal: Journal of Medical Microbiology [Category] SARS, 진단, 치료기술,

[키워드] Accuracy Affect alleviate alternatives approach arising CDC chain Chain Reaction clinically Combination Combined comparable Comparative Control correlated COVID-19 COVID-19 infection COVID-19 pandemic diagnosing diagnostic disease control downstream Effect Environmental impact evaluated extraction facilitate Healthcare provider healthcare providers heat inactivation heat-inactivation method infection control LightCycler 480 II Measures N1 and N2 National NHS outcome Patient performed polymerase chain reaction positive prevention probe protocol protocols provided purified RNA qRT-PCR qScript R 2 Rapid reaction reagent reagents reduce reducing reported required Resilience Result reverse transcription RNA extraction Roche RT-qPCR testing SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 genome SARS-CoV-2 virus sensitivity service supply chains Swab test result tested the SARS-CoV-2 virus Treatment Viral viral genomes viral inactivation viral transport media virus inactivation writing
[DOI] 10.1099/jmm.0.001301 PMC 바로가기 [Article Type] Comparative Study

A combined oro-nasopharyngeal swab is more sensitive than mouthwash in detecting SARS-CoV-2 by a high-throughput PCR assay

결합된 구강-비인두 면봉은 고처리량 PCR 분석으로 SARS-CoV-2를 검출하는 데 구강 세정제보다 더 민감합니다.

Comparative Study

Published on 2021-03-182022-09-10
Journal: Infection [Category] MERS, SARS, 진단, 치료기술,

Evaluation of 18 commercial serological assays for the detection of antibodies against SARS-CoV-2 in paired serum samples

한 쌍의 혈청 샘플에서 SARS-CoV-2에 대한 항체 검출을 위한 18가지 상용 혈청학적 분석 평가

Comparative Study

Published on 2021-03-172022-09-10
Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, 치료기술,

[키워드] ACRO acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody testing assays Boson Characteristics coronavirus cross-reactivity detect diagnose diagnoses diagnostic ECLIA ELISA epitope evaluated healthcare worker Healthcare workers highest ICU patient ICU Patients IgA IgG IgG ELISA IgM Infection Orient Patient performed POCT presence of antibody respiratory Roche SARS-CoV-2 SARS-CoV-2 antibody sensitivity sera Serological assay serological test Serological tests serology serum sample severe acute respiratory syndrome Coronavirus severe symptom severe symptoms specificity supplementary material Symptoms Test variety
[DOI] 10.1007/s10096-021-04220-7 PMC 바로가기 [Article Type] Comparative Study

Antibody titers and rapid antigen testing in elderly patients with SARS-CoV-2 pneumonia vs. staff of ICU and “Covid-19” wards

Article

Published on 2021-03-152022-11-01
Journal: GMS Hygiene and Infection Control [Category] COVID-19,

Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection

경도 SARS-CoV-2 감염에 대한 항체 반응의 이질성 및 혈청 역전의 시계열 분석 및 기계론적 모델링

Research Paper

Published on 2021-03-022022-09-11
Journal: EBioMedicine [Category] SARS, 진단, 치료법,

[키워드] Analysis Anti-S1 antibody antibody levels antibody production Antibody Response antibody titres assays Asymptomatic Blood blood sampling changes in clearance Comparisons correlated deaths evaluate Extended faster finding Follow-up funding greater healthcare worker heterogeneity heterogeneous Humoral immunity identify IgG Infection infections London Longevity Longitudinal studies longitudinal study Mathematical modelling mechanism median Mild mild infection mild SARS-CoV-2 infection neutralising antibody titre NIHR participant PCR peak population level positive production rate prospective cohort study protective humoral immunity pseudovirus pseudovirus neutralizing antibody recruited reduction in reductions in required response Roche S1 domain SARS-CoV-2 SARS-CoV-2 epidemic SARS-COV-2 infection SARS-CoV-2, Serology, Mathematical modelling, Sero-reversion semi-quantitative serological analysis serological response serology sustained Symptom time transition Viral viral nucleocapsid protein viral spike was performed Wellcome Trust
[DOI] 10.1016/j.ebiom.2021.103259 PMC 바로가기 [Article Type] Research Paper

Detection of Coronavirus in Tear Samples of Hospitalized Patients With Confirmed SARS-CoV-2 From Oropharyngeal Swabs

구강 인두 면봉에서 SARS-CoV-2가 확인된 입원 환자의 눈물 샘플에서 코로나바이러스 검출

Article

Published on 2021-03-012022-09-11
Journal: Cornea [Category] SARS, 치료기술,

[키워드] analyzed automatically case sery Chain Reaction chemosis Confirmed conjunctival conjunctival hyperemia contagiousness coronavirus coronavirus RNA detect detection disease fluid overload hospitalized patient hospitalized patients hyperemia intensive care intensive care unit Laboratory ocular Ocular surface ophthalmoscopy Oropharyngeal oropharyngeal swab oropharyngeal swabs Patient PCR performed polymerase chain polymerase chain reaction positive Real-time PCR recruited Respiratory failure Roche Sample SARS-CoV-2 SARS-CoV-2 positive patients submitted suffered Swab Tear tears tissue Viral viral conjunctivitis viral shedding was used
[DOI] 10.1097/ICO.0000000000002562 PMC 바로가기 [Article Type] Article

Prevalence of SARS-CoV-2 IgG antibodies in a large prospective cohort study of elite football players in Germany (May-June 2020): implications for a testing protocol in asymptomatic individuals and estimation of the rate of undetected cases

독일의 엘리트 축구 선수에 대한 대규모 전향적 코호트 연구(2020년 5월-6월)에서 SARS-CoV-2 IgG 항체의 유병률: 무증상 개인의 테스트 프로토콜 및 감지되지 않은 사례의 비율 추정에 대한 의미

Observational Study

Published on 2021-03-012022-09-12
Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 임상, 진단,

[키워드] acute respiratory syndrome age All participant antibody assay assays asymptomatic individual chemiluminescent immunoassay CLIA coronavirus correlated COVID-19 cumulative diagnostic eight ELISA Elite Epidemiology geographical distribution Germany IgG IgG positivity Immunity implication incidence Infection infections men nasopharyngeal neutralisation assay Neutralization assay oropharyngeal swabs participant PCR PCR-negative prospective cohort study protocol reference standard Roche SARS-CoV-2 SARS-CoV-2 IgG antibody Seroprevalence Shutdown Significant soccer study period tested unique was determined was used were used
[DOI] 10.1016/j.cmi.2020.11.033 PMC 바로가기 [Article Type] Observational Study

Recent Advances in the Evaluation of Serological Assays for the Diagnosis of SARS-CoV-2 Infection and COVID-19

SARS-CoV-2 감염 및 COVID-19 진단을 위한 혈청학적 분석 평가의 최근 발전

Public Health

Published on 2021-02-182022-09-11
Journal: Frontiers in Public Health [Category] MERS, SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advance automated chemiluminescence immunoassay CLIA collected coronavirus COVID-19 diagnosis of SARS-CoV-2 diagnostic DiaSorin ECLIA and ELISA Elecsys electrochemiluminescence immunoassay ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated FIVE iFlash IgA IgA antibodies IgA antibody IgG IgG and IgM IgM immunochromatographic assay Infection investigated lateral flow lateral flow immunochromatographic assay LFIA LIAISON Nasopharyngeal swab onset of symptom PCR assay plasma sample plasma samples point-of-care positive predominant recent reference standard respiratory retrospective retrospective diagnosis reverse transcriptase Roche RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RT-PCR SARS-CoV-2-specific antibodies sensitivity Sensitivity and specificity Serological assay serological test Serological tests severe acute respiratory syndrome Coronavirus Shenzhen specificity subject
[DOI] 10.3389/fpubh.2020.620222 PMC 바로가기 [Article Type] Public Health

Variable Performance in 6 Commercial SARS-CoV-2 Antibody Assays May Affect Convalescent Plasma and Seroprevalence Screening

6가지 상용 SARS-CoV-2 항체 분석의 다양한 성능이 회복기 혈장 및 혈청유병률 스크리닝에 영향을 미칠 수 있음

Article

Published on 2021-02-112022-09-11
Journal: American journal of clinical pathology [Category] MERS, 진단, 치료기술, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody Antibody assays assessment Beckman Coulter Centaur Cohort convalescent plasma coronavirus COVID-19 defined Definition detected antibody disease Donor donors Euroimmun greater Hospitalization IgA IgG independent Infection less molecular nucleocapsid Patient performance produced producing required respiratory Roche SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 nucleocapsid Screening sensitivity Seroconversion serologic serologic assay serology Seroprevalence Siemen Siemens specificity Spike protein symptom onset variable vista were assessed
[DOI] 10.1093/ajcp/aqaa228 PMC 바로가기 [Article Type] Article