Baricitinib improves respiratory function in patients treated with corticosteroids for SARS-CoV-2 pneumonia: an observational cohort study바리시티닙은 SARS-CoV-2 폐렴에 대한 코르티코스테로이드 치료 환자의 호흡 기능을 개선합니다: 관찰 코호트 연구Observational Study Published on 2021-01-052022-09-11 Journal: Rheumatology (Oxford, England) [Category] 임상, 진단, 치료제, [키워드] adjusted arterial oxygen partial pressure Baricitinib block viral entry Combination Corticosteroid Corticosteroids COVID-19 cytokine Cytokine storm discharge end point enrolled European FiO2 greater HCQ High-dose Hospitalization IMPROVE inhibitor Jak Janus kinase Lopinavir Lopinavir/ritonavir moderate moderate to severe network Observational cohort study observational study oxygen oxygen partial pressure oxygen saturation PaO2 partial pressure Patient patients treated patients with moderate patients with SARS-CoV-2 pharmacoepidemiology pharmacovigilance pneumocyte Pneumocytes Pneumonia Prevent primary end point proportion Pulmonary function pulse oximetry reduction required requiring supplemental oxygen Respiratory function risk Ritonavir SARS-CoV-2 SARS-CoV-2 pneumonia secondary severe SARS-CoV-2 SpO2 SpO2/FiO2 Statistics supplemental oxygen Viral viral entry Weighting [DOI] 10.1093/rheumatology/keaa587 PMC 바로가기 [Article Type] Observational Study
Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application: a prospective, observational study모바일 애플리케이션의 대규모 자체 보고 데이터를 사용하여 영국의 COVID-19 감염 핫스팟 감지: 전향적, 관찰 연구Observational Study Published on 2021-01-012022-09-11 Journal: The Lancet. Public Health [Category] Fulltext, MERS, 임상, 치료제, [키워드] 95% CI age assessment assessments calculated chain change chronic chronic disease community infection community transmission complementary Council country COVID COVID Symptom Study app COVID-19 COVID-19 infection dataset Department detect Disease surveillance effective Engineering England estimate foundation Government granular healthy heart help highest highlight hotspot identify incidence incidence of COVID-19 incidence rate incidence rates increases in information Intervention Local Logistic regression Markov Markov chain Medical Research Council National observational study office ONS pandemic PCR tests Poisson Prevalence provided recorded Region reported Reproduction number resource RT-PCR RT-PCR test RT-PCR tests Science sensitivity Society spread of COVID-19 Statistics survey Swab Swab test Symptom Symptoms test results the disease Wellcome Trust Zoe Global [DOI] 10.1016/S2468-2667(20)30269-3 PMC 바로가기 [Article Type] Observational Study
Efficacy of Traditional Chinese Medicine, Maxingshigan-Weijing in the management of COVID-19 patients with severe acute respiratory syndrome: A structured summary of a study protocol for a randomized controlled trial중증 급성 호흡기 증후군이 있는 COVID-19 환자 관리에 대한 중국 전통 의학 Maxingshigan-Weijing의 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-12-232022-08-31 Journal: Trials [Category] MERS, SARS, 임상, 치료제, [키워드] 1:1 acute respiratory syndrome acute respiratory syndrome coronavirus addition administration Affiliated Hospital age allergic allergies anorexia anti-bacterial Anti-viral anticipated Anxiety Arm asked Asymptomatic automatically aversion blinded Blinding Blood tinged blood tinged sputum both groups Care carried center checklist Chenpi chest pain chest X-ray Chinese Chinese Clinical Trial Registry Chinese herbal medicines clinical clinical symptom clinical trials clinically Cold comparator Patients composed control group Controlled trial coronavirus cough COVID-19 COVID-19 patient criteria critical patient critical patients defined diarrhea disease Diseases dissemination distension Dizziness dry mouth dysphoria effective Efficacy element Eligible patients ephedra exclusion criteria expectoration female Fever Follow-up four-point scale Gypsum H1N1 H1N1 influenza headache hematopoietic system Herba Ephedra herbal medicine hospital IBM IBM Corp IMPROVE improvement in both group include Inclusion inclusion and exclusion criteria inclusion criteria individual Influenza Informed consent Inpatient Insomnia Kaplan-Meier method kidney Kidney function lactation less liver log-rank test malaise male management Maxingshigan-weijing mechanical ventilation Medicine Melon Mild mild clinical symptoms multicenter multiple organ failure muscular nasal nasal obstruction nausea nausea and vomiting negative test nucleic acid number objective open Open-label oral administration outcome participant Patient patients Peach pharyngalgia Pneumonia positive Pregnancy previous study Primary outcome Professor proportion protocol Radix random random allocation random number generator randomisation randomised Randomized Randomized controlled trial randomly divided receive recruited registry reported researcher respiratory Respiratory failure respiratory symptom Sample size SARS-CoV-2 SARS-CoV-2 nucleic acid Scoring second secondary Secondary outcomes Semen sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity Shock Shortness of breath statistical analysis Statistical power Statistics status Study protocol suffering supplementary material supportive care survival survival time sweating Symptom symptomatic Symptoms System TCM temperature test results the median therapy total score Traditional Traditional Chinese medicine treated Treatment trial protocol Trial registration Trichosanthe Trichosanthes Kirilowii university USA Version virus pneumonia vomiting website wheezing Winter Withdrawal [DOI] 10.1186/s13063-020-04970-3 PMC 바로가기 [Article Type] Letter
Assessment of the potential role of atmospheric particulate pollution and airborne transmission in intensifying the first wave pandemic impact of SARS-CoV-2/COVID-19 in Northern ItalyResearch Article Published on 2020-12-212022-10-28 Journal: Bulletin of Atmospheric Science and Technology [Category] COVID-19, [키워드] activate Activation acute respiratory syndrome addition Airborne virus transmission amplifying assessment atmospheric average carried China collected Combination Concentration concentrations consequence contagious coronavirus correlated correlation coefficient COVID-19 COVID-19 infection death dose doubling Effect effective enhanced Environmental pollution Epidemiologic parameters exceeded Factor Fatality rate First wave humans incidence indicated infected individual infected patient Infection infection rate infective Italian Italy mortality rate Northern region occurred pandemic Particle Particles pathology PM10 PM2.5 Region reported Respiratory system SARS-CoV-2 Spread statistical analysis Statistics Transmission transported Valley virus virus carrier while WHO Wuhan [DOI] 10.1007/s42865-020-00024-3 PMC 바로가기 [Article Type] Research Article
COVID-19 cycles and rapidly evaluating lockdown strategies using spectral analysisArticle Published on 2020-12-172022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, SARS, [키워드] Analysis Bayesian cause contribute country COVID-19 COVID-19 case declines Epidemic Epidemiology estimate evaluate Factors help indicated lockdown recorded Spectral spectral analysis Statistics suppressed the epidemic wavelength [DOI] 10.1038/s41598-020-79092-6 PMC 바로가기 [Article Type] Article
Public Health Interventions for the COVID-19 Pandemic Reduce Respiratory Tract Infection-Related Visits at Pediatric Emergency Departments in TaiwanPublic Health Published on 2020-12-162022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Admission Analysis Asthma categories children COVID-19 COVID-19 pandemic database dataset Department diagnose Diagnosis disease effective Emergency Fever handwashing Health Infection intensive care Intervention Memorial N95 masks National pediatric Pediatric emergency department prevented proportion Public Public health intervention Public health interventions reducing respiratory respiratory tract respiratory tract infection retrieved risk of infection SARS-CoV-2 significant decrease significant difference significantly significantly higher significantly lower social distancing Statistics subgroup analysis surgical System Taiwan tract Transmission transmitted urinary tract infection urinary tract infections wearing masks [DOI] 10.3389/fpubh.2020.604089 PMC 바로가기 [Article Type] Public Health
Some Questions to Our Chinese Colleagues Pioneering Research Into Coronavirus Disease 2019 (COVID-19)Medicine Published on 2020-12-082022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] analyzed association baseline body mass index Cardiology carried Chinese consequence Coronavirus disease 2019 COVID-19 described disease electrocardiogram electrocardiographic excluded Follow-up Hospital admission household size Infection information Laboratory test many case missing value Mortality neurologic no difference outcome pandemic Patient patients physician prognostic indicator Psychiatric question report reported Statistics were excluded with COVID-19 [DOI] 10.3389/fmed.2020.594623 PMC 바로가기 [Article Type] Medicine
Time dynamics of COVID-19Article Published on 2020-12-032022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] Case fatality rate country covariate COVID-19 COVID-19 case cumulative Data analysis death Decreased determine doubling Effect Epidemiology facilitate functional information initial positive Regression model Scientific data Statistics time trajectory [DOI] 10.1038/s41598-020-77709-4 PMC 바로가기 [Article Type] Article
Non-COVID-19 excess deaths by age and gender in the United States during the first three months of the COVID-19 pandemicArticle Published on 2020-12-012023-07-06 Journal: Public health [Category] SARS, [키워드] COVID-19 Fatality risk Statistics [DOI] 10.1016/j.puhe.2020.10.004 PMC 바로가기
Mortality reduction in 46 severe Covid-19 patients treated with hyperimmune plasma. A proof of concept single arm multicenter trial과면역 혈장으로 치료받은 46명의 중증 코비드-19 환자의 사망률 감소. 개념 증명 단일 암 다기관 시험Article Published on 2020-12-012022-09-12 Journal: Haematologica [Category] MERS, SARS, 진단, [키워드] 95%CI Administered antibody ARDS Bilateral changes Chest chest X-ray Cohort conducted convalescent CPAP CRP died disease elevated enrolled expected hospital Hyperimmune plasma Intubated Laboratory LDH male mechanical ventilation monoclonal antibodies Mortality multicenter Multicenter trial Neutralizing null hypothesis occurred outcome paO2/fiO2 Patient patients patients treated plasma Potential treatment radiologic Randomized controlled trial reduction in respiratory secondary Serious Adverse Event severity Statistics Survivors Treatment was obtained weaning [DOI] 10.3324/haematol.2020.261784 PMC 바로가기 [Article Type] Article