Impact of previous exposure to SARS-CoV-2 and of S-Trimer (SCB-2019) COVID-19 vaccination on the risk of reinfection: a randomised, double-blinded, placebo-controlled, phase 2 and 3 trialSARS-CoV-2 및 S-Trimer(SCB-2019) COVID-19 백신에 대한 이전 노출이 재감염 위험에 미치는 영향: 무작위 배정, 이중 맹검, 위약 대조, 2상 및 3상 시험Clinical Trial Published on 2022-07-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 1:1 95% CI addition Alpha assigned attack rates B.1.1.7 B.1.351 B.1.617.2 B.1.621 baseline Beta calculate CEPI Clover Coalition confirmed case COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccine dose double-blind double-blinded Efficacy enrolled Evidence evidence of exposure to FIVE groups hospitalisation Impact injection site pain Innovation IQVIA Lambda Local lowest moderate-to-severe COVID-19 multicentre no evidence of P.1 participant Participants Phase 2 Placebo placebo-controlled placebo-controlled trial Primary outcome Primary outcomes protection Protective randomised Randomly Rate reactogenicity Real-time PCR receive recipients recombinant Reinfection reported response risk SARS-CoV-2 SARS-CoV-2-naïve participants SCB-2019 Secondary analyses secondary analysis Serious Adverse Event Serious Adverse Events severe adverse events severe COVID-19 severity subsequent subset symptomatic systemic adverse event systemic adverse events technology Trial USA vaccination Vaccine vaccine dose vaccine efficacy variant variants Viral variants with COVID-19 [DOI] 10.1016/S1473-3099(22)00144-X PMC 바로가기 [Article Type] Clinical Trial
Saliva versus Upper Respiratory Swabs: Equivalent for Severe Acute Respiratory Syndrome Coronavirus 2 University Screening while Saliva Positivity Is Prolonged After Symptom Onset in Coronavirus Disease 2019 Hospitalized Patients타액 대 상부 호흡기 면봉: 중증 급성 호흡기 증후군 코로나바이러스 2 대학 선별 검사에 해당하며 코로나바이러스 질병 2019 입원 환자의 증상 발병 후 타액 양성이 연장됨Article Published on 2022-07-012022-09-11 Journal: The Journal of molecular diagnostics : JMD [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Asymptomatic Cohort collected comparable coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 equivalent faculty hospital hospitalized patient hospitalized patients nare offer Onset pandemic populations positive Prolonged proportion Real-time PCR reopening respiratory Saliva SARS-CoV-2 SARS-CoV-2 detection School Schools Screening screening methods sensitivity severe acute respiratory syndrome Coronavirus specimen study cohort Swab symptom onset symptomatic symptomatic and asymptomatic symptomatic COVID-19 tested university University of Pennsylvania upper upper respiratory [DOI] 10.1016/j.jmoldx.2022.03.012 PMC 바로가기 [Article Type] Article
Voice Sequelae Following Recovery From COVID-19Case report Published on 2022-07-012022-10-05 Journal: Journal of Voice [Category] 바이오마커, 진단, 치료기술, [키워드] analyzed approach Biomechanical correlates caused clinical collected COVID-19 digestive system Diseases Health identify Infectious disease laryngeal men men and women mucosa paralysis participant Patient professional Result symptomatic System therapy Trigger voice voice analysis Vowel sounds weakness women [DOI] 10.1016/j.jvoice.2022.06.033 [Article Type] Case report
Myocarditis and Cardiac Complications Associated With COVID-19 and mRNA Vaccination: A Pragmatic Narrative Review to Guide Clinical PracticeReview article Published on 2022-07-012022-10-05 Journal: Heart, Lung and Circulation [Category] COVID19(2023년), SARS, 바이오마커, [키워드] appear Biomarker cardiac cardiac complication Cardiac magnetic resonance imaging caused clinical Clinical course Clinical practice Complication coronavirus Coronavirus disease 2019 COVID-19 COVID-19 infection echocardiography effective Endemic Evidence Guidance guide heterogeneity incidence Infection infections International lack management manuscript Mild mRNA mRNA vaccination myocardial involvement myocarditis narrative National Patient patient group patients with COVID-19 Pericarditis Practice provide recovering from COVID-19 resource review risk risk stratification SARS-CoV-2 symptomatic the SARS-CoV-2 virus troponin vaccination widespread [DOI] 10.1016/j.hlc.2022.03.003 [Article Type] Review article
Effect of a home-based inspiratory muscular training programme on functional capacity in patients with chronic COVID-19 after a hospital discharge: protocol for a randomised control trial (InsCOVID trial)퇴원 후 만성 COVID-19 환자의 기능 능력에 대한 가정 기반 흡기 근육 훈련 프로그램의 효과: 무작위 대조 시험 프로토콜(InsCOVID 시험)Article Published on 2022-07-012022-09-11 Journal: BMJ Open Respiratory Research [Category] 임상, [키워드] 1:1 acute respiratory syndrome acute respiratory syndrome coronavirus Admission analysis of variance approved baseline blinded coronavirus COVID-19 COVID-19 patients Declaration of Helsinki discharged Effect eight eligible patient enrolled Ethics evaluate exercise exercise intolerance fatigue finding functional functional capacity groups Helsinki hospital Hospital admission hospital discharge IMPROVE inspiratory muscle Intervention muscles muscular National outcome Patient peer-reviewed Pneumonia primary endpoint protocol pulmonary rehabilitation randomised randomised controlled trial receive registration number Regulation Research Research Ethics Research Ethics Committee respiratory muscles Supervised exercise Symptom symptomatic Symptoms the primary endpoint Trial usual care usual care alone variance [DOI] 10.1136/bmjresp-2022-001255 PMC 바로가기 [Article Type] Article
Factors associated with clinical progression to severe COVID-19 in people with cystic fibrosis: A global observational studyObservational Study Published on 2022-07-012022-10-05 Journal: Journal of cystic fibrosis : official journal of t [Category] COVID19(2023년), SARS, 유전자 메커니즘, 임상, [키워드] 95%CI acute SARS-CoV-2 infection Analysis AOR body mass index CFTR Clinical characteristics Cohort coronavirus country COVID-19 Cystic cystic fibrosis demographics diabetes effective Factor fibrosis hospital hospitalisation hospitalised increase in International Logistic regression Older age outcome outcomes oxygen Patient prescription Primary outcome progression protective effect recipients reduced reported risk SARS-CoV-2 SARS-COV-2 infection severe COVID-19 Severe infection significantly solid-organ transplant supplemental oxygen Supplemental oxygen therapy symptomatic therapy Transplant Vaccine was used [DOI] 10.1016/j.jcf.2022.06.006 PMC 바로가기 [Article Type] Observational Study
Clinical Performance of a Lateral Flow SARS-CoV-2 Total Antibody Assay측면 흐름 SARS-CoV-2 총 항체 분석의 임상 성능Article Published on 2022-06-302022-09-12 Journal: The journal of applied laboratory medicine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI 95%CI Abbott Abbott SARS-CoV-2 IgG antibody assays clinical collected COVID-19 COVID-19 pandemic demonstrated Diagnosis diagnostic Flow Immunity Inflammatory Lateral lateral flow negative RT-PCR Patient patients Pediatric patient performance positive relative RT-PCR RT-PCR testing SARS-CoV-2 Sensitivity and specificity Serological assay serology specimen specimens symptom onset symptomatic syndrome Test Total utility [DOI] 10.1093/jalm/jfac003 PMC 바로가기 [Article Type] Article
Viral RNA Load and Infectivity of SARS-CoV-2 in Paired Respiratory and Oral Specimens from Symptomatic, Asymptomatic, or Postsymptomatic Individuals무증상, 무증상 또는 무증상 개인의 호흡기 및 구강 표본에서 SARS-CoV-2의 바이러스 RNA 부하 및 감염성Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, [키워드] anterior nares Asymptomatic Asymptomatic individuals asymptomatic patient asymptomatic patients bodily secretions Care care provider classic close contact collected COVID-19 COVID-19 diagnosis Critical diagnosed with COVID-19 diagnostic diagnostic sensitivity diagnostic testing epidemiological FIVE followed by Frequency Health Health care help individual individuals infection with SARS-CoV-2 Infectious virus Infectivity information initial Isolation load molecular nare nares nasopharyngeal oral patients platform positive individual positive individuals provide quarantine respiratory RNA RT-PCR Saliva saliva specimens Sample Sampling frequency SARS-CoV-2 secretion sensitivity specimen specimens Surveillance Swab swabs symptomatic symptomatic patient Symptomatic patients tested The diagnostic sensitivity understanding viral RNA load virus detection virus infectivity virus isolation was determined [DOI] 10.1128/spectrum.02264-21 PMC 바로가기 [Article Type] Article
Evaluation of Four Point of Care (POC) Antigen Assays for the Detection of the SARS-CoV-2 Variant OmicronSARS-CoV-2 변이체 오미크론 검출을 위한 4가지 진료 시점(POC) 항원 분석 평가Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] Abbott Analysis analytical sensitivity Antigen assays Asymptomatic average Cell culture contributing to correlated Cycle threshold value ddPCR Delta delta variant detect detectable detection diagnostics digital PCR Dilution discrepancies discrepancy Ensuring evaluated Genome highest Infectious virus infectious virus titer limit limit of detection LOD log manuscript molecular N gene omicron Omicron variant POC Point point of care point-of-care positive quantified Rapid antigen tests Real-time PCR reduced replicate RNA SARS-CoV-2 specimen Spread swab sample symptomatic tested the SARS-CoV-2 vaccinated individuals variant variant of SARS-CoV-2 Viral viral stock viral stocks virus stock virus titer [DOI] 10.1128/spectrum.01025-22 PMC 바로가기 [Article Type] Article
Bilateral Emphysematous Pyelonephritis Associated with COVID Pneumonia: A Case ReportCOVID 폐렴과 관련된 양측 폐기종성 신우신염: 증례 보고Case Reports Published on 2022-06-272022-09-11 Journal: The American journal of case reports [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] ACE2 acute respiratory distress acute respiratory distress syndrome angiotensin Angiotensin-converting enzyme Antimicrobial therapy Bilateral caused Cell cells changes in Combination Coronavirus infection COVID COVID-19 COVID-19 infection Diabetic Diagnosis Emergency Emphysematous emphysematous pyelonephritis Fever general condition human cell human cells Inflammation inflammatory change inflammatory changes inflammatory process Injury kidneys linkage local inflammation lung parenchyma movement nephrectomy outcome Pain parenchymal Pneumonia potentiation progressed pyelonephritis receptor renal renal abnormalities renal abnormality report respiratory distress respiratory symptoms risk factor SARS-CoV-2 SARS-CoV-2 virus Sepsis shivering symptomatic syndrome the patient the SARS-CoV-2 virus therapy treat Treatment tubular cell Urinary tract Viral pneumonia worse prognosis [DOI] 10.12659/AJCR.936370 PMC 바로가기 [Article Type] Case Reports