Impact of COVID-19 on the oral health of adults in Wuhan and China: results of a nationwide online cross-sectional questionnaire surveyResearch Article Published on 2021-03-262022-10-28 Journal: BMC Oral Health [Category] COVID-19, Fulltext, SARS, [키워드] affected bleeding breath Care China collected conducted COVID-19 cross-sectional cross-sectional survey evaluate Frequency gingival bleeding Health Impact maintaining not differ oral health participant Prevalence problem problems psychologically question questionnaire Questionnaire survey Result significantly significantly more suffered supplementary material the epidemic toothbrushing Treatment Wuhan [DOI] 10.1186/s12903-021-01533-z PMC 바로가기 [Article Type] Research Article
Essential properties and pitfalls of colorimetric Reverse Transcription Loop-mediated Isothermal Amplification as a point-of-care test for SARS-CoV-2 diagnosisSARS-CoV-2 진단을 위한 현장 진단 테스트로서의 비색 역전사 루프 매개 등온 증폭의 필수 속성 및 함정Research Article Published on 2021-03-262022-09-10 Journal: Molecular Medicine [Category] SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] addition clinical samples Cluster color change colorimetric detection correlation Ct values demonstrated described detect determinate Diagnosis diagnosis of COVID-19 diagnostic diagnostics Essential false-negative false-negative results indication indications Internal control Interpretation lead Loop-mediated isothermal amplification manuscript molecular Molecular biology molecular diagnostics nuance performed point of care point-of-care positive produced quantification reducing Result resulting reverse transcription RT-LAMP RT-qPCR SARS-CoV-2 sensitivity specificity supplementary material Symptom technique Viral Viral load virus with color [DOI] 10.1186/s10020-021-00289-0 PMC 바로가기 [Article Type] Research Article
Diabetes, even newly defined by HbA1c testing, is associated with an increased risk of in-hospital death in adults with COVID-19Observational Study Published on 2021-03-262022-10-04 Journal: BMC Endocrine Disorders [Category] Coronavirus, 임상, [키워드] Admission age Analysis China Chinese coronavirus disease Coronavirus disease 2019 COVID-19 Cox regression analysis D-dimer death defined diabete diabetes diagnosed Factor Final group groups hemoglobin Hemoglobin A1c In-hospital death in-hospital mortality rate increased mortality increased risk independent risk factor Inpatient investigated Kaplan-Meier survival analysis Mortality mortality rate multivariate Cox regression Organ failure outcomes patients patients with COVID-19 Prevalence Probability reported Result Retrospective study Screening significantly increased supplementary material survival Tongji Hospital Undiagnosed diabetes was determined with COVID-19 Wuhan [DOI] 10.1186/s12902-021-00717-6 PMC 바로가기 [Article Type] Observational Study
Testing olfactory dysfunction in acute and recovered COVID-19 patients: a single center study in ItalyCovid-19 Published on 2021-03-262022-10-30 Journal: Neurological Sciences [Category] COVID-19, MERS, SARS, [키워드] acute COVID-19 acute illness acutely ill patient Anosmia antibody appear association Clinical characteristics cohorts of patient coronavirus disease COVID-19 demographic dysfunction Frequency hospitalized patient Hyposmia investigated Italian population Italy median Molecular diagnosis molecular test nasal olfactory olfactory dysfunction olfactory test Olfactory testing participant Patient positive recovered reported Result SARS-CoV-2 scored significantly higher single center subject subjects supplementary material Symptom Symptoms symptoms onset Testing was performed [DOI] 10.1007/s10072-021-05200-7 PMC 바로가기 [Article Type] Covid-19
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effectResearch Article Published on 2021-03-262022-10-27 Journal: BMC Bioinformatics [Category] COVID-19, [키워드] Analysis antigenic antigenic protein antigenicity BCG Combination COVID-19 Evidence explain HBV humans identify immunogenic immunogenicity induce investigated Measle MMR OPV pandemic disease protective effect Protein Putative protection regions Result SARS-CoV-2 SARS-CoV-2 protein sequence severe pneumonia severity supplementary material Tetanus the disease Vaccine Vaccines Variation [DOI] 10.1186/s12859-021-04045-3 PMC 바로가기 [Article Type] Research Article
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effectResearch Article Published on 2021-03-262022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, COVID-19, Fulltext, SARS, [키워드] Analysis antigenic antigenic protein antigenicity BCG Combination COVID-19 Evidence explain HBV humans identify immunogenic immunogenicity induce investigated Measle MMR OPV pandemic disease protective effect Protein Putative protection regions Result SARS-CoV-2 SARS-CoV-2 protein sequence severe pneumonia severity supplementary material Tetanus the disease Vaccine Vaccines Variation [DOI] 10.1186/s12859-021-04045-3 PMC 바로가기 [Article Type] Research Article
Meta-analysis: COVID-19 diagnosis in chest CT—master key for radiologistsReview Published on 2021-03-252022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] Analysis Chest Chest CT chest CT scan China consolidation coronavirus COVID-19 COVID-19 diagnosis CT scan declining determine diagnosis of COVID-19 diagnostic Dyspnea early stage GGO increase in indicate initial International Isolation last stage lesion linear Meta-analysis National observation outbreak Patient PCR test pleural effusion Prevalence radiologist reported RT-PCR SARS-CoV-2 sensitivity statistical analysis supplementary material Symptom systematic review the disease [DOI] 10.1186/s43055-021-00457-6 PMC 바로가기 [Article Type] Review
Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatmentResearch Published on 2021-03-252022-11-01 Journal: Cell & Bioscience [Category] COVID-19, [키워드] Affect Analysis animal animal model attenuate bioinformatic analysis cause conserved COVID-19 demonstrated disease Drosophila Effect effective Express expression Genes highly pathogenic Host human protein identify in vivo inhibit inhibiting mechanism muscle organism pathogenic pathogenicity phenotype Protein reduced Result resulting SARS-CoV-2 SARS-CoV-2 genes SARS-CoV-2 protein SARS-CoV2 selinexor supplementary material tested tissue tissues Toxicity transgenic Treatment various tissues viability viral gene Virus-host interaction XPO1 [DOI] 10.1186/s13578-021-00567-8 PMC 바로가기 [Article Type] Research
Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by SelinexorResearch Published on 2021-03-252022-11-01 Journal: Cell & Bioscience [Category] COVID-19, [키워드] affinity cause Cell cells cellular cellular damage characterization COS-7 cells COVID-19 cytotoxicity disease drug candidate Endoplasmic reticulum examined highest highly pathogenic Host host protein identify inhibit inhibitor interact Interaction lysosomal mechanism membrane membranes over-expressed pathogenic pathogenicity Protein Proteins purification Rae1 Ranbp2 Result reveal SARS-CoV-2 SARS-CoV-2 protein selinexor subcellular localization supplementary material tested the SARS-CoV-2 the SARS-CoV-2 genome Toxicity XPO1 [DOI] 10.1186/s13578-021-00568-7 PMC 바로가기 [Article Type] Research
Human mobility and poverty as key drivers of COVID-19 transmission and controlResearch Article Published on 2021-03-252022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] adverse effect analyzed applied Applying Cell Compliance Contact mixing patterns coronavirus COVID-19 COVID-19 mortality COVID-19 transmission curtail develop driver Effective strategies Effectiveness Efficacy epidemiological evaluated exhibited help helping hotspot Human human mobility identify IMPROVE incidence indicated individual Intervention lifted lockdown lockdowns morbidity morbidity and mortality outbreak Outbreaks overall mortality parameters reduce Region regions resource Result risk SIR model supplementary material Transmission Transmission model transmission rates [DOI] 10.1186/s12889-021-10561-x PMC 바로가기 [Article Type] Research Article