active treatment – Page 2 – Communicable Diseases Research

Predictors of poor seroconversion and adverse events to SARS-CoV-2 mRNA BNT162b2 vaccine in cancer patients on active treatment

활성 치료 중인 암 환자에서 SARS-CoV-2 mRNA BNT162b2 백신에 대한 불량한 혈청 전환 및 유해 사례의 예측인자

Observational Study

Published on 2021-12-012022-09-11
Journal: European journal of cancer (Oxford, England : 1990 [Category] MERS, SARS, 바이오마커, 임상, 진단,

Serologic response to COVID-19 infection and/or vaccine in cancer patients on active treatment

활성 치료 중인 암 환자의 COVID-19 감염 및/또는 백신에 대한 혈청학적 반응

Article

Published on 2021-12-012022-09-11
Journal: ESMO open [Category] SARS, 변종, 치료법,

[키워드] active treatment anti-S Anti-S1 antibody antibody response rate Antibody titer biologic BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine booster Cancer cancer patient Cancer patients Chemotherapy Chemotherapy treatment Cohort control group COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines domain dose evaluated Health care Health care worker humoral identify Immunocompromised Immunocompromised patient Immunocompromised patients immunogenic immunogenicity Immunologic immunologic response Immunotherapy Infection less metastatic disease multiple regression model natural infection Neutralizing antibody titer Odds ratio other treatment other treatments Patient positive positive response reduced response rate S1/S2 SARS-CoV-2 variant SARS-CoV-2 variants serologic Serologic response serologic test serologic tests serological surveillance shown significantly solid tumor solid tumors Specific subgroup subgroups the SARS-CoV-2 Treatment tumors vaccination Vaccine vaccine doses Virological were measured
[DOI] 10.1016/j.esmoop.2021.100283 PMC 바로가기 [Article Type] Article

Association of Antineoplastic Therapy With Decreased SARS-CoV-2 Infection Rates in Patients With Cancer

암 환자의 SARS-CoV-2 감염률 감소와 항종양 요법의 연관성

Article

Published on 2021-11-012022-09-11
Journal: JAMA Oncology [Category] Fulltext, MERS, 치료제,

[키워드] 95% CI ACE2 ACE2 gene active treatment additional sensitivity analyses additional sensitivity analysis age Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 anti-SARS-CoV-2 Antineoplastic antineoplastics association Cancer cancer type cancers cell lines cellular center Cohort cohort study Compound compounds confounders COVID-19 pandemic database Decreased determine disrupt downregulation drug treatment evaluated exhibited expression female finding gemcitabine gene expression signature identify in silico analysis inhibitor library male measure Memorial mTOR multivariable analysis New York novel Odds ratio outcome Patient patients Patients with cancer PI3K positive Rate receiving reduced Replication retrospective cohort SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test signature significantly lower statistically steroid steroid use therapy these compound these compounds treated Treatment
[DOI] 10.1001/jamaoncol.2021.3585 PMC 바로가기 [Article Type] Article

Metabolic dysfunction associated fatty liver disease and coronavirus disease 2019: clinical relationship and current management

대사 기능 장애 관련 지방간 질환 및 코로나바이러스 질환 2019: 임상 관계 및 현재 관리

Review

Published on 2021-10-032022-09-10
Journal: Lipids in Health and Disease [Category] MERS, SARS, 유전자 메커니즘,

[키워드] ACE2 active treatment acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin angiotensin converting enzyme caused Clinical management contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patient deaths develop disease Disruption Drug-induced liver injury dysfunction enzyme exacerbated expression Fatty liver fatty liver disease Glucose Host hypoxic increased risk indicated infected with COVID-19 Injury International investigated Liver injury MAFLD management mechanism mechanisms metabolic Metabolic disorders metabolic dysfunction multifactorial pandemic of COVID-19 Patient patients with COVID-19 present prevalence of COVID-19 prevalent previous study progression promoted receptor recommendation respiratory respiratory infection respiratory outcomes SARS-CoV-2 severity of COVID-19 systemic inflammatory tendency the patient Treatment Viral Youth
[DOI] 10.1186/s12944-021-01564-z PMC 바로가기 [Article Type] Review

The neutralizing antibody response post COVID-19 vaccination in patients with myeloma is highly dependent on the type of anti-myeloma treatment

골수종 환자의 Covid-19 백신 접종 후 중화 항체 반응은 항-미 일종 치료의 유형에 크게 의존합니다.

Multicenter Study

Published on 2021-08-022022-09-01
Journal: Blood Cancer Journal [Category] MERS, SARS, 임상, 진단, 치료법,

Lower response to BNT162b2 vaccine in patients with myelofibrosis compared to polycythemia vera and essential thrombocythemia

진성적혈구증가증 및 본태성 혈소판증가증에 비해 골수섬유증 환자에서 BNT162b2 백신에 대한 낮은 반응

Letter to the Editor

Published on 2021-07-292022-09-12
Journal: Journal of Hematology & Oncology [Category] SARS, 진단,

Evaluation of Seropositivity Following BNT162b2 Messenger RNA Vaccination for SARS-CoV-2 in Patients Undergoing Treatment for Cancer

암 치료를 받는 환자에서 SARS-CoV-2에 대한 BNT162b2 메신저 RNA 백신 접종 후 혈청 양성 평가

Research

Published on 2021-05-282022-09-12
Journal: JAMA Oncology [Category] MERS, SARS, 진단,

[키워드] 95% CI accompanied active treatment age analyses Analysis analyzed anti-S Antibody Response Antibody titer anticancer Beilinson Hospital blood sample Blood samples BNT162b2 BNT162b2 vaccine Cancer center Chemotherapy cohort study comparison Comparisons conducted Control control group COVID-19 COVID-19 disease Davidoff defined develop domain Enrollment evaluate exhibited Factor finding greater healthy control healthy controls high risk higher risk IgG IgG antibodies IgG antibody IgG titer IgG titers immunoassay Immunotherapy Importance intravenous measure median men messenger Messenger RNA multivariable analyses multivariable analysis objective outcome participant Participants Patient Patients with cancer Point Primary outcome prospective cohort study receiving Relevance required Research respond Result RNA SARS-CoV 2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose second messenger secondary Secondary outcomes seropositive Seropositivity serum sample serum samples setting severe COVID-19 disease significantly significantly lower solid tumor solid tumors Study participants Support systemic therapy systemic treatment the patient therapy titers Treatment Tumor tumors vaccination vaccine dose
[DOI] 10.1001/jamaoncol.2021.2155 PMC 바로가기 [Article Type] Research

Clinical course and management of 73 hospitalized moderate patients with COVID-19 outside Wuhan

우한 외 지역의 COVID-19 입원 중등도 환자 73명의 임상 경과 및 관리

Research Article

Published on 2021-05-132022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 치료기술, 치료제,

[키워드] active treatment acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission analyzed blood biochemistry Chest chest tightness clinical Clinical course coronavirus cough Course died discharge fatigue Fever Follow-up Hospitalization Hospitalized hospitalized patient hospitalized patients hyperglycemia IMPROVE Infection investigated Laboratory less Liver function lymphopenia majority management median median age medical record medical records men moderate myocardial enzymes nucleic acid nucleic acid test on admission Patient patients with COVID-19 positive positively correlated Prognosis proportion recurrence respiratory SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 patients severe acute respiratory syndrome Coronavirus survivor Survivors Symptom Symptoms the median the SARS-CoV-2 Treatment Viral Viral detection virus carrier virus carriers women Wuhan
[DOI] 10.1371/journal.pone.0249655 PMC 바로가기 [Article Type] Research Article

Incidence of COVID-19 in outpatients with cancer receiving active treatment in the context of a pandemic: An Andalusian cohort study

Short communication

Published on 2021-04-012022-10-05
Journal: Seminars in oncology [Category] SARS, 치료법,

The right immune-modulation at the right time: thymosin α1 for prevention of severe COVID-19 in cancer patients

적시에 적절한 면역 조절: 암 환자의 중증 코로나19 예방을 위한 티모신 α1

Review

Published on 2021-02-042022-09-10
Journal: Future Oncology [Category] MERS, SARS, 임상,

[키워드] Abstract active treatment Adults anticancer approach approaches cancer patient Cancer patients caner children clinical trial COVID-19 curative disease drug effective Efficacy EudraCT Evidence explain favor function help Hypothesis immune system incurable incurable disease individuals lack modulate multicenter offer Open-label outcome patient population Patients with cancer phase Prevent prevention preventive treatment produced Prophylactic Prophylaxis PROTECT randomized study rationale receiving risk SARS-CoV-2 scientific evidence severe COVID-19 Severe infection severe infections Support thought thymosin thymus Treatment Trial vaccination Vaccine vaccine efficacy
[DOI] 10.2217/fon-2020-0754 PMC 바로가기 [Article Type] Review