Lab-on-chip assay of tumour markers and human papilloma virus for cervical cancer detection at the point-of-care Research Published on 2022-05-242022-10-05 Journal: Scientific Reports [Category] 바이오마커, [키워드] Affect amplify analytical sensitivity assays Cancer Cancer cells cervical cancer Combination complement demonstrated DNA Efficacy expression HPV Infection ISFET isothermal amplification limit of detection majority marker molecular target mRNA point-of-care resolved selected single copy strain tissue tissue samples tissues transcriptase transistor virus [DOI] 10.1038/s41598-022-12557-y [Article Type] Research
COVID-19 associated coagulopathy and thrombosis in cancerResearch article Published on 2022-05-012022-10-05 Journal: Thrombosis research [Category] COVID19(2023년), SARS, 임상, [키워드] adverse outcome amplify anti-cancer treatment Antithrombotic Cancer cancer patient caused clinical study clinically Coagulation Coagulopathy Combination COVID-19 COVID-19 infection COVID-19 vaccination D-dimer disease Disseminated intravascular coagulation effective Efficacy and safety evaluated haematological malignancy hypercoagulable immune response Immune suppression IMPROVE incidence Infection intensity lung cancer management outcome Patient patients Prophylaxis Pulmonary embolism risk Safe SARS-CoV-2 selected seroconversion rate Severe COVID-19 Infection Specific thromboembolic complications thrombosis thrombotic microangiopathy vaccination venous thromboembolic [DOI] 10.1016/j.thromres.2021.12.006 [Article Type] Research article
Inhaled antibodies: Quality and performance considerations흡입 항체: 품질 및 성능 고려 사항Review Published on 2022-04-292022-09-12 Journal: Human vaccines & immunotherapeutics [Category] MERS, 진단, [키워드] administration Aerosols amplify antibodies antibody Asthma COVID-19 dosage drug Dry powder inhaler Formulation Infectious disease involved Local Lung disease Lungs Measures molecular nebulizer offer Protein Quality receptor specificity stability target the disease Therapeutics therapy Treatment variety virus [DOI] 10.1080/21645515.2021.1940650 PMC 바로가기 [Article Type] Review
Types and Applications of Nicking Enzyme-Combined Isothermal AmplificationNicking 효소 결합 등온 증폭의 유형 및 응용Review Published on 2022-04-212022-09-11 Journal: International Journal of Molecular Sciences [Category] 진단, 치료제, [키워드] amplification amplify application biochemical cleavage clinics Community complexity COVID-19 diagnostic diagnostics Disadvantages Efficiency enzyme Enzymes hospitals Immunodiagnosis IMPROVE Intensive isothermal isothermal amplification limitations molecular molecular detection Molecular diagnosis Nicking nicking enzyme. nucleic acid nucleic acids outbreak overcome platform POCT point-of-care Research shown subject target targets temperature Type [DOI] 10.3390/ijms23094620 PMC 바로가기 [Article Type] Review
Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19Research article Published on 2022-04-142022-10-05 Journal: Blood advances [Category] SARS, 바이오마커, 비임상, [키워드] activated Activation aggregate amplification amplify amplifying Analysis approach assays binding CD16 Coagulation Combination COVID-19 Critically ill patient driving Evidence Ex vivo exhibited expression fibrinogen function functional high risk highlight HLA-DR hypercoagulability hyperinflammation identify in vitro indicated Inflammation Inflammatory Inflammatory cytokine Inflammatory mediators inflammatory monocyte Interaction interleukin-1β life-threatening mechanism mechanisms monocyte P-selectin pathogenesis of COVID-19 Patient pharmacological Platelet platelet activation Platelets presenting proinflammatory cytokines receptor response RNA-sequencing SARS-COV-2 infection secretion severe COVID-19 Signaling single-cell subset thromboembolic complications Thromboinflammation tissue tumor necrosis factor-α with COVID-19 [DOI] 10.1182/bloodadvances.2021006680 [Article Type] Research article
Can periodontal pockets and caries lesions act as reservoirs for coronavirus?치주낭과 충치 병변이 코로나바이러스의 저장소 역할을 할 수 있습니까?Article Published on 2022-04-012022-09-11 Journal: Molecular oral microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplify approach Asymptomatic Can caries Chain Reaction coronavirus cross-sectional cross-sectional study Ct value detect dissemination evaluate Genes infections information knowledge lesion lesions negative control participant Patient patients periodontal pocket polymerase chain polymerase chain reaction positive positive control positive COVID-19 real-time polymerase chain reaction reservoir reservoirs RT-PCR S gene SARS-CoV-2 SARS-CoV-2 detection sensitivity severe acute respiratory syndrome Coronavirus specificity symptomatic the mean the SARS-CoV-2 virus while [DOI] 10.1111/omi.12362 PMC 바로가기 [Article Type] Article
Profiling RT-LAMP tolerance of sequence variation for SARS-CoV-2 RNA detectionSARS-CoV-2 RNA 검출을 위한 서열 변이의 RT-LAMP 내성 프로파일링Article Published on 2022-03-242022-09-11 Journal: PLoS ONE [Category] SARS, 변종, 치료기술, 치료제, [키워드] adopted affecting amplification amplify bases clinical laboratory creating Critical deletions Detection sensitivity diagnostic diagnostic test diagnostic tests dramatic increase Effect highlight identify knowledge Laboratory LAMP molecular molecular diagnostic tests Mutation no effect nucleic acid nucleic acid amplification Point mutation primer primer set primer sets Profiling qPCR assays Reactions reduced regions RNA sequence robust RT-LAMP RT-qPCR RT-qPCR assays SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 RNA detection SARS-CoV-2 sequence SARS-CoV-2 variant SARS-CoV-2 variants sensitivity sequence variation significantly Spread These data Tolerance utility variant Viral RNA viral RNA detection virus [DOI] 10.1371/journal.pone.0259610 PMC 바로가기 [Article Type] Article
Immunity debt or vaccination crisis? A multi-method evidence on vaccine acceptance and media framing for emerging COVID-19 variants면책 부채 또는 예방 접종 위기? 신종 코로나바이러스 감염증(COVID-19) 변종에 대한 백신 수용 및 미디어 프레이밍에 대한 다중 방법 증거Article Published on 2022-03-152022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] amplify Analysis approach community health conflict Consequences Coverage COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines Critical Delta Effect effective engage Evidence Frame Framing theory influence mechanism media omicron Omicron variants Outbreaks pandemic Participants Population prevalent Public Public acceptance for vaccination raise reassurance rising scientific evidence vaccination Vaccine Vaccine hesitancy variant variants [DOI] 10.1016/j.vaccine.2022.01.055 PMC 바로가기 [Article Type] Article
Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevitySirt1과 AMPK를 통한 페룰산과 베르베린은 건강한 장수의 세포 정화 촉진제로 작용할 수 있습니다Review Published on 2022-03-012022-09-11 Journal: Open Heart [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] activating Activation AMPK amplify amplifying anthocyanin Anti-inflammatory effects antioxidant Apoptosis appear autophagy bacterial metabolite benefit berberine biogenesis boost carotid carotid artery carotid artery diseases Cell cell survival cellular cellular senescence Chinese clinically complementary Concentration conjunction coronary angiography deficit detect DNA DNA repair echocardiography Effect endothelial ENhance enzyme expression ferulic acid function functions Health health benefits healthy independent Inflammation inhibiting mechanism mediator mitochondrial molecular basis mRNA NAD+ NF-kB nicotinamide Nrf2 nutraceutical Phase 2 promote promoter Protective protective effect protein level protein levels SARS-CoV-2 spike protein SIRT1 Spike protein survival synergistic the SARS-CoV-2 tissues Toxicity transcription factor turn [DOI] 10.1136/openhrt-2021-001801 PMC 바로가기 [Article Type] Review
Replace, amplify, transform: a qualitative study of how postgraduate trainees and supervisors experience and use telehealth for instruction in ambulatory patient careResearch Published on 2022-02-222022-10-28 Journal: BMC Medical Education [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] activities activity amplify can be used coded conducted COVID-19 pandemic Critical Data analysis data-driven develop Educational technology effective ENhance help implementation in-person visit indicated median observation organized Patient Patient care pediatric PGME Postgraduate medical education recommendation Result supplementary material telehealth Telemedicine thematic analysis trainee [DOI] 10.1186/s12909-022-03175-3 PMC 바로가기 [Article Type] Research