ankylosing spondylitis

[키워드] activating Activation allele Alter analysis ankylosing spondylitis Antigen Arthritis Autoimmune canonical carriage cause Cell cells class Cohort Combination combinations complement condition conducted contribute contributing to controls damage decrease develop disease dosage Endoplasmic reticulum epistatic interaction epistatic interactions ERAP1 Factor Genetic genetic factors genetic information genotype data Haplotype haplotypes healthy healthy control HLA HLA allele HLA alleles HLA ligand HLA ligands HLA-B human leukocyte antigen human population identify Immune cell immune cells immune system immune-cell Immune-mediated immune-mediated diseases Immunopathogenesis imputation individual Infectious disease inflammatory activity Inflammatory arthritis Inflammatory response inhibitory receptor Inhibitory Receptors instance instances Interaction investigated joint joints killer immunoglobulin-like receptors KIR KIR gene KIR genes KIR-HLA KIR3DL1 KIRs leukocyte Ligand ligands lymphocyte Lymphocytes malignant malignant cells natural killer Pathogenesis pathogenic variant pelvis proinflammatory provide receptor regulated repertoire Research risk shifting specificity spine spondylitis T-cells threshold tissue
[DOI] 10.1371/journal.pgen.1008906 PMC 바로가기 [Article Type] Research Article