Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial확인 된 또는 의심되는 박테리아 감염 (Batch)으로 입원 한 어린이의 바이오 마커 유도 항생제 치료 기간 : 무작위 대조 시험을위한 프로토콜Paediatrics Published on 2022-01-252022-09-10 Journal: BMJ Open [Category] Fulltext, SARS, 바이오마커, 임상, [키워드] Adverse drug reactions adverse effect Algorithm Analysis Antibiotic treatment antibiotic use Antibiotics approved Bacterial infection best Biomarker C reactive protein children clinician commenced conducted conjunction control arm Controlled COVID-19 pandemic death Diagnostic microbiology discharge dissemination East Ethics Follow-up Health hospital Hospital stay HRA include infections Infectious diseases International Intervention intravenous antibiotics National Health Service NHS North outcome paediatric intensive & critical care PCT peer-reviewed procalcitonin protocol public health randomised controlled trial RCT REC recruit reduce registration number Relapse Research respond Safety measure secondary Secondary outcomes treated Treatment trial protocol Two-arm utility West [DOI] 10.1136/bmjopen-2020-047490 PMC 바로가기 [Article Type] Paediatrics
Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza박테리아 동시 감염 및 지속적인 호중구 기관지 폐포 염증에 대한 비정형 반응은 인플루엔자와 중요한 COVID-19를 구별합니다Research Article Published on 2022-01-112022-09-12 Journal: JCI Insight [Category] 진단, 치료기술, [키워드] activating Antibiotic treatment Bacterial bacterial coinfections BAL BAL fluid blood sample bronchoalveolar Bronchoalveolar lavage CCL7 chemokine chemokines chemotactic factor circulating Cohort collected comparable Concentration coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical Critically ill critically ill COVID-19 patients CXCL1 CXCL11 CXCL12 CXCL8 cytokine Cytokines decrease effector cell elafin elevated fluids G-CSF highlighting IL-1 β IL-17A IL-1ra Immunological response immunology Inflammation Influenza Invasive mechanical ventilation leukocyte lung Lungs Lymphocytes mechanically ventilated patient mechanically ventilated patients metalloproteinase Monocytes neutrophil neutrophilic Neutrophils NK cell NK cells parameter pathophysiology patients with COVID-19 patients with influenza Protease inhibitor protease inhibitors proteolytic activity severe coronavirus disease Tissue Inhibitor TNF- α Treatment Viral pneumonia [DOI] 10.1172/jci.insight.155055 PMC 바로가기 [Article Type] Research Article
Iranian Pediatric COVID-19 Epidemiology and Clinical CharacteristicsResearch Article Published on 2021-12-152022-10-31 Journal: The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale [Category] COVID-19, [키워드] addition age Antibiotic treatment Antibiotics Antiviral average Care children clinical Clinical sign conducted Corona cough COVID-19 diagnosed died disease epidemiological epidemiological data evaluate Features Fever FIVE GGO Hospitalized Infection information Iran Khorramabad Laboratory majority malignancy medical record mortality rate MOST Novel coronavirus opacity Oxygen therapy Prevalence respiratory Result SARS-CoV-2 Spread steroid Steroids Symptom Tehran Treatment underlying disease [DOI] 10.1155/2021/4914371 PMC 바로가기 [Article Type] Research Article
How Does COVID-19 Pandemic Impact on Incidence of Clostridioides difficile Infection and Exacerbation of Its Gastrointestinal Symptoms?Medicine Published on 2021-12-132022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Clostridioides difficile infection addition Affect all age groups alteration Antibiotic therapy Antibiotic treatment Antibiotics antimicrobial Antiviral Bacterial infection cephalosporins Clostridioide Clostridioides difficile infection colonization resistance complicate contributing to Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 infection COVID-19 pandemic COVID-19 patients death develop diarrhea elderly Elderly patient elderly patients Exacerbation excessive use explain facilitated fecal Gastrointestinal gut microbiota healthcare highlight Hospitalized hospitalized patient immunomodulatory drug Impact incidence infection with COVID-19 lung involvement manifestation microbial infection Mortality nasopharyngeal NSAIDS organ outcome pathogen Pathogenesis Pathogens Patient patients with COVID-19 persistence physician presence of comorbidity receiving reduced risk risk factor SARS-CoV-2 SARS-CoV-2 viral particle severe disease Spread Symptom Transmissibility Transmission virus entry widespread with COVID-19 [DOI] 10.3389/fmed.2021.775063 PMC 바로가기 [Article Type] Medicine
Mobility of β -lactam resistance under ampicillin treatment in gut microbiota suffering from pre-disturbance암피실린 치료 중 미리 교란된 장내 미생물군에서 β-락탐 내성의 이동성Article Published on 2021-12-092024-07-29 Journal: Microbial Genomics [Category] 살모넬라증, [키워드] Antibiotic resistance Antibiotic treatment gut microbiota intestinal inflammation plasmid transfer [DOI] 10.1099/mgen.0.000713 PMC 바로가기
Infliximab rescue therapy in a patient with acute severe ulcerative colitis and coronavirus disease 2019 followed by Escherichia coli 0157:H7 infection: a case report급성 중증 궤양성 대장염 및 코로나바이러스 질환 2019에 이어 대장균 0157:H7 감염 환자에서 Infliximab 구조 요법: 증례 보고Case Reports Published on 2021-12-012022-09-12 Journal: Croatian Medical Journal [Category] 진단, [키워드] administration antibiotic Antibiotic treatment biologic Case report caused clinical response coronavirus disease COVID-19 disease dominant driven by Escherichia coli general condition induce Infection Inflammatory bowel disease infliximab management Mild Necrosis parameter Patient positive risk SARS-CoV-2 SARS-CoV-2-positive patient second serological test severity tested the patient therapy treat treated Treatment ulcerative colitis uremic syndrome [DOI] 10.3325/cmj.2021.62.634 PMC 바로가기 [Article Type] Case Reports
A Challenge of COVID—19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent PatientCase Report Published on 2021-11-262022-10-30 Journal: Medicina [Category] COVID-19, MERS, SARS, [키워드] Streptococcus gordonii Antibiotic treatment biologic Blood challenge clinician Coronaviral COVID-19 COVID-19 infection COVID-19 pandemic Culture diagnosed Diagnosis disease disorder Endocarditis febrile Fever headache Infection infectious endocarditis infective investigation Manifestations Microbiome Moderate COVID-19 myalgias Oral microbiome outcomes Pain Pathogenesis Patient Pneumonia positive reported risk factor RT-PCR Streptococcus sweating Symptom syndrome the patient Treatment vegetation virulence weight loss while [DOI] 10.3390/medicina57121298 PMC 바로가기 [Article Type] Case Report
Antibiotics for Fever Among Children: Findings From the Surveillance for Enteric Fever in India Cohorts어린이의 발열에 대한 항생제: 인도 집단의 장티푸스 감시 결과Article Published on 2021-11-152024-07-29 Journal: Nanoscale [Category] 살모넬라증, [키워드] acute febrile illness Antibiotic treatment Cohort India pediatric SEFI [DOI] 10.1093/infdis/jiab115 PMC 바로가기
Partial oral antibiotic treatment for bacterial brain abscess: an open-label randomized non-inferiority trial (ORAL)Randomized Controlled Trial Published on 2021-11-122022-10-04 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 Admission age all-cause mortality Alpha Antibiotic therapy Antibiotic treatment Antibiotics assigned Bacterial blinded Brain Brain abscess caused Cerebral abscess cognitive complications composite endpoint conducted Controlled trial criteria Date Denmark effective Endpoint EudraCT favor Follow-up France Health hospital Immunocompromise include independent International intravenous intraventricular investigator-initiated Netherlands non-inferiority non-inferiority trial Open-label oral outcome parallel group Partial Patient patients Pregnancy primary endpoint Pseudomona Quality of life randomization Randomized Randomized controlled trial recommendation recruitment Registered rupture Sample size scale secondary severe adverse events standard treatment suggested Treatment Tuberculosis [DOI] 10.1186/s13063-021-05783-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Amoebic liver abscess in a COVID-19 patient: a case reportCase Report Published on 2021-11-042022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] abdominal pain acute respiratory syndrome Affect Amoebiasis Amoebic liver abscess Antibiotic treatment Case report caused clinical picture coronavirus coronavirus disease country COVID-19 described diarrhoea discharged disease Dyspnoea Entamoeba histolytica exploratory Fever hospital hospitalisation hypoxaemia Interaction intestinal knowledge liver malaise Manifestations Nasopharyngeal swab parasite Pathogens pathophysiological patient with COVID-19 polymerase chain positive receiving reported SARS-CoV-2 serology similarities Stool examination the patient tomography Treatment Venezuela was performed [DOI] 10.1186/s12879-021-06819-9 PMC 바로가기 [Article Type] Case Report