On the potential for discontinuing atovaquone-proguanil (AP) ad-hoc post-exposure and other abbreviated AP-regimens: Pharmacology, pharmacokinetics and perspectivesarticle Published on 2023-04-302024-09-01 Journal: Travel Medicine and Infectious Disease [Category] 말라리아, [키워드] Antimalarials Atovaquone-proguanil Chemoprophylaxis malaria Travelers [Article Type] article
Synthesis and antimalarial activity of amide and ester conjugates of siderophores and ozonidesarticle Published on 2023-04-302024-09-01 Journal: BioMetals [Category] 말라리아, [키워드] Antimalarials cerebral malaria iron chelation Siderophore-ozonide conjugates [Article Type] article
Pre-referral rectal artesunate is no “magic bullet” in weak health systems사전 의뢰 직장 아르테순산은 취약한 건강 시스템에서 "마법의 총알"이 아니다.Article Published on 2023-03-302024-08-01 Journal: BMC Medicine [Category] 말라리아, [키워드] Antimalarials artesunate Case management Effectiveness health systems quality of care Rectal artesunate Referral severe malaria [DOI] 10.1186/s12916-023-02777-y PMC 바로가기
Malaria patient spectrum representation in therapeutic clinical trials of uncomplicated malaria: a scoping review of the literature치료적 임상 시험에서 단순 말라리아 환자 스펙트럼 표현: 문헌에 대한 범위 검토Article Published on 2023-02-102024-08-01 Journal: Malaria Journal [Category] 말라리아, [키워드] Antimalarials clinical trial malaria patient selection review Uncomplicated malaria [DOI] 10.1186/s12936-023-04441-5 PMC 바로가기
N-sulfonylpiperidinedispiro-1,2,4,5-tetraoxanes exhibit potent in vitro antiplasmodial activity and in vivo efficacy in mice infected with P. berghei ANKAarticle Published on 2022-12-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] Antimalarials Endoperoxides P. berghei P. falciparum Tetraoxanes [Article Type] article
From DC18 to MR07: A Metabolically Stable 4,4′-Oxybisbenzoyl Amide as a Low-Nanomolar Growth Inhibitor of P. falciparumArticle Published on 2022-11-042024-08-29 Journal: ChemMedChem [Category] 말라리아, [키워드] Antimalarials In silico pharmacophore mapping In vitro metabolic stability malaria Plasmodium falciparum
New Transmission-Selective Antimalarial Agents through Hit-to-Lead Optimization of 2-([1,1′-Biphenyl]-4-carboxamido)benzoic Acid DerivativesArticle Published on 2022-11-042024-08-29 Journal: ChemBioChem [Category] 말라리아, [키워드] Antimalarials epigenetics Gametocytes heterocycles inhibitors Plasmodium
The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasitesarticle Published on 2022-09-302024-09-01 Journal: Traffic [Category] 말라리아, [키워드] Antimalarials malaria Plasmodium falciparum Protein Transport small molecule libraries [Article Type] article
Community-Based Malaria Testing Reduces Polypharmacy in a Population-Based Survey of Febrile Illness in Western Kenyaarticle Published on 2022-08-312024-09-01 Journal: International Journal of Public Health [Category] 말라리아, [키워드] Antibiotics Antimalarials Fever malaria Malaria testing polypharmacy [Article Type] article
In silico study indicates antimalarials as direct inhibitors of SARS-CoV-2-RNA dependent RNA polymeraseIn silico 연구는 항말라리아제가 SARS-CoV-2-RNA 의존성 RNA 중합효소의 직접적인 억제제임을 나타냅니다.Article Published on 2022-08-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] SARS, 치료제, [키워드] active site active sites acute respiratory syndrome coronavirus Amino acid amino acid residue amino acid residues amodiaquine antimalarial Antimalarials Antiviral ATP binding caused Chloroquine co-crystallized Compound conserved coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 crystal structure docked docking results global pandemic Hydroxychloroquine in silico in silico inhibition. indicate inhibitor interactions involved MD simulation molecular pandemic PDB PDB ID performed Poliovirus RdRP RdRps Remdesivir Replication researcher residue residues respiratory RNA RNA dependent RNA polymerase RNA polymerase RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2-RNA dependent RNA polymerase screened Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Simulation study Structure suggested Superimposition Transcription Treatment was used [DOI] 10.1080/07391102.2021.1871956 PMC 바로가기 [Article Type] Article