The cannabinoid receptor-1 gene interacts with stressful life events to increase the risk for problematic alcohol use칸나비노이드 수용체-1 유전자는 스트레스가 많은 생활 사건과 상호작용하여 문제가 있는 알코올 사용의 위험을 증가시킵니다Article Published on 2022-03-232022-09-11 Journal: Scientific Reports [Category] 변종, [키워드] Activation adulthood Affect alcohol Alcohol Use Disorders Identification Test association Audit baseline binding Brain childhood CNR1 conducted COVID-19 pandemic Cross-sectional analyses cross-sectional analysis death develop disorders DNA event Evidence Factor functional Genetic variant genetic variants Genome-wide association study genotyped habituation humans identification identify implicated interact Interaction interactions Model Neuroticism not significant nucleotide outcome outcomes Personality Trait polymorphism predicted predictor provided Psychiatric public health reason for receptor repeated reported Research risk risk allele single nucleotide Single nucleotide polymorphism SLE Stress Stressor stressors substance Substance use substance use disorders Support Swedish targets Test traits Treatment turn [DOI] 10.1038/s41598-022-08980-w PMC 바로가기 [Article Type] Article
Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B.1.1.7 in England: an observational cohort study영국의 SARS-CoV-2 계통 B.1.1.7과 관련된 사망률 및 중환자실 입원: 관찰 코호트 연구Observational Study Published on 2021-11-012022-09-10 Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 변종, 임상, [키워드] 28-day mortality 95% CI adjusted adjusted hazard ratio adjusted hazard ratios Admission age association Asthma Audit B.1.1.7 body-mass body-mass index cardiovascular disease case mix CCU chronic obstructive chronic obstructive pulmonary disease Clinical outcome clinical outcomes Cohort Community Comorbidities Comorbidity COVID-19 test COVID-19 testing Critical care Critically ill dependency Deprivation diabetes diagnostic died division Ethnicity exposure to finding funding geographical region groups hazard ratios hospital HRs hypertension immunocompromised condition increased risk independent independent of Infection infection with COVID-19 information Lineage Lineage B.1.1.7 measure Medical Science metastatic disease molecular Mortality National Observational cohort study obstructive pulmonary disease on type on types organ support overall mortality Oxford Patient patients with SARS-CoV-2 positive positive sample primary care Public Health England pulmonary disease QResearch receiving reported respiratory Respiratory disease risk S-gene SARS-CoV-2 SARS-COV-2 infection Sex smoking status Sociodemographic factor the SARS-CoV-2 two groups University of Oxford variant variant of SARS-CoV-2 virus strain Wellcome Trust [DOI] 10.1016/S1473-3099(21)00318-2 PMC 바로가기 [Article Type] Observational Study
Small-scale release of non-gene drive mosquitoes in Burkina Faso: from engagement implementation to assessment, a learning journey부르키나파소에서 유전자 드라이브가 없는 모기의 소규모 방출: 참여 실행에서 평가까지, 학습 여정Research Published on 2021-10-092024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] Audit Evaluation gene drive Genetically modified mosquitoes release malaria Responsible research stakeholder engagement [DOI] 10.1186/s12936-021-03929-2 PMC 바로가기 [Article Type] Research
Elderly Patient Care: A New Reality of the SARS-CoV-2 PandemicOpinion Published on 2021-10-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] administration adverse outcome age alimentary applied Audit Care Comorbidity conducted coughing COVID-19 deficiency demonstrated Disabled Dyspnea elderly employee employment European country hygiene identify implementation increase involved knowledge lack limit management modify mortality rate New No. 3 pandemic pathogen Patient Poland Post-infection Prevent preventing infection prevention professionals public health REALITY responders risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections second wave selected Spread Symptom the SARS-CoV-2 training transmitted virus spread [DOI] 10.14336/AD.2021.0222 PMC 바로가기 [Article Type] Opinion
Primary care for patients with respiratory tract infection before and early on in the COVID-19 pandemic: an observational study in 16 European countriesObservational Study Published on 2021-07-292022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] 95% CI Antibiotics Audit Belgium C reactive protein Care Characteristics clinical assessments consultation Contact country COVID-19 COVID-19 pandemic Denmark described diagnostic difference Effectiveness European European country Follow-up Germany Greece Health insight Laboratory testing management medication National pandemic Patient Poland PPE primary care proportion provided quality in healthcare Registered reported respiratory infections respiratory tract infection responses SARS-CoV-2 SARS-CoV-2 testing Symptom Threats Variation [DOI] 10.1136/bmjopen-2021-049257 PMC 바로가기 [Article Type] Observational Study
Risk of missing colorectal cancer with a COVID-adapted diagnostic pathway using quantitative faecal immunochemical testing정량적 분변 면역화학 검사를 사용한 코로나 적응 진단 경로로 결장직장암 누락 위험Original Article Published on 2021-07-062022-09-12 Journal: BJS Open [Category] 진단, [키워드] Audit bowel Cancer cancers Colonoscopy Colorectal cancer Combination COVID-19 CT scan data set diagnostic healthcare services immunochemical Local pathway patients performed PrEP Prevalence Quantitative reduced referred to residual risk Result risk Sensitivity and specificity symptomatic patient Symptomatic patients trade-off Triage [DOI] 10.1093/bjsopen/zrab056 PMC 바로가기 [Article Type] Original Article
Implementation of the ERAS (Enhanced Recovery After Surgery) protocol for colorectal cancer surgery in the Piemonte Region with an Audit and Feedback approach: study protocol for a stepped wedge cluster randomised trial: a study of the EASY-NET project감사 및 피드백 접근 방식을 사용하여 Piemonte 지역에서 대장암 수술을 위한 ERAS(수술 후 회복 강화) 프로토콜 구현: 계단형 쐐기형 클러스터 무작위 시험을 위한 연구 프로토콜: EASY-NET 프로젝트 연구Article Published on 2021-06-032022-09-11 Journal: BMJ Open [Category] SARS, 임상, 치료기술, [키워드] Activation adopted application approach approved assigned Audit Care changes in clinically Cluster Colorectal cancer Colorectal surgery Committee complications Control of pain COVID-19 COVID-19 pandemic detect endpoints enhanced ERAS ethical committee Ethics expected feedback four groups Health Health care hospital Hospital stay incidence include Italy LOS management multicentre outcome Pain pathway Patient peer-reviewed postoperative Postoperative Complications Primary outcome promote protocol quality in health care randomised Randomised trial Randomly randomly divided reduce reduction Region registration number Sample size Satisfaction secondary Secondary outcomes Statistical power stratified Stress Study protocol surgery surgical Surgical stress Volume [DOI] 10.1136/bmjopen-2020-047491 PMC 바로가기 [Article Type] Article
Organisation and timeline of measures in French psychiatric establishments during the first wave of the COVID-19 epidemic: EvOlu’Psy studyResearch Published on 2021-06-022022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] Admission Adults Audit Care changes in concerning COVID-19 cross-sectional domain First wave France French Full-time health-care hospital hospitalisation infection control management measure Mental mental health Mental health departments mental illness MOST organisation pandemic Patient Psychiatric psychiatric facility questionnaire reported required respond response restriction Result risk Risk factors severe COVID-19 social distancing Somatic Specific supplementary material was performed [DOI] 10.1186/s12888-021-03293-0 PMC 바로가기 [Article Type] Research
Organisation and timeline of measures in French psychiatric establishments during the first wave of the COVID-19 epidemic: EvOlu’Psy studyResearch Published on 2021-06-022022-10-27 Journal: BMC Psychiatry [Category] COVID-19, [키워드] Admission Adults Audit Care changes in concerning COVID-19 cross-sectional domain First wave France French Full-time health-care hospital hospitalisation infection control management measure Mental mental health Mental health departments mental illness MOST organisation pandemic Patient Psychiatric psychiatric facility questionnaire reported required respond response restriction Result risk Risk factors severe COVID-19 social distancing Somatic Specific supplementary material was performed [DOI] 10.1186/s12888-021-03293-0 PMC 바로가기 [Article Type] Research
The impact of COVID-19 pandemic on vascular registries and clinical trials코로나19 팬데믹이 혈관 등록 및 임상 시험에 미치는 영향Review Published on 2021-06-012022-09-11 Journal: Seminars in vascular surgery [Category] 임상, [키워드] affecting Audit clinical trial clinical trials coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 pandemic Data collection Decline desire Device Disruption Enrollment Europe Factor flexible forms Germany highlight increased mortality initiative insertion magnitude morbidity Needs Assessment network New organization organizations outcome outcomes pandemic Patient patient safety patients Preliminary data problem Quality Quality improvement registry reported Research risk Society study group study groups surgery the disease the United State The United States Trial United Kingdom United States variable Vascular Vascular surgery Volume [DOI] 10.1053/j.semvascsurg.2021.04.001 PMC 바로가기 [Article Type] Review