Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s Research Published on 2022-07-122022-10-05 Journal: Cell Discovery [Category] 변종, [키워드] ACE2 base omicron Receptor binding SARS-CoV-2 [DOI] 10.1038/s41421-022-00431-0 [Article Type] Research
Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineagesOmicron 하위 계통을 포함하여 다양한 SARS-CoV-2 변이체에 대해 매우 효과적인 3회 용량 백신의 강력한 광범위 중화 항체의 선택 및 구조적 기반Article Published on 2022-07-012022-09-11 Journal: Cell Research [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] base effective neutralizing antibody omicron SARS-CoV-2 variants Selection vaccinee [DOI] 10.1038/s41422-022-00677-z PMC 바로가기 [Article Type] Article
Insertion-and-Deletion Mutations between the Genomes of SARS-CoV, SARS-CoV-2, and Bat Coronavirus RaTG13SARS-CoV, SARS-CoV-2 및 박쥐 코로나바이러스 RaTG13의 게놈 간의 삽입 및 삭제 돌연변이Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 base bases bat bat coronavirus RaTG13 Complete coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) developmental distribution FIVE Frame gene sequence Genome genome sequence Genome sequences genomes Inconclusive INDEL indels insertion insertion-and-deletion mutation mechanism MOST Mutation mutation rate mutations Noncoding region nonstructural protein 3 Open reading frame ORF ORF8 ORF8 gene ORF8 genes Point mutation point mutations protein 3 RaTG13 replaced REPLACED BY replacement S1 domain SARS-CoV SARS-CoV-2 SARS-CoV-2 genome sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus (SARS-CoV) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Spike protein the SARS-CoV-2 genome the spike protein viral genome virus [DOI] 10.1128/spectrum.00716-22 PMC 바로가기 [Article Type] Article
Effects of COVID-19 Mental Health Interventions Among Children, Adolescents, and Adults Not Quarantined or Undergoing Treatment Due to COVID-19 Infection: A Systematic Review of Randomised Controlled TrialsCOVID-19 감염으로 인해 격리되지 않았거나 치료를 받고 있지 않은 아동, 청소년 및 성인 사이의 COVID-19 정신 건강 개입의 영향: 무작위 대조 시험의 체계적인 검토Article Published on 2022-05-012022-09-11 Journal: Canadian journal of psychiatry. Revue canadienne d [Category] 임상, [키워드] 95% CI 95% confidence interval Anxiety Autoimmune base children Controlled controlled trials coronavirus country COVID-19 COVID-19 infection database Depression depressive symptom Depressive symptoms Effect effective eligible English expressive feasible French General population group therapy heterogeneity high risk hospitalised Infection Internet Intervention Living systematic review mental health mental health interventions not significant nous Older participant Participants Population post-intervention Psychological outcomes psychological outcomes. randomised controlled trial reduced reported review risk of bia searched significantly SMD standardized mean difference Support Swedish Symptom tested the United State therapy Treatment Trial trials United States Worry [DOI] 10.1177/07067437211070648 PMC 바로가기 [Article Type] Article
Epidemiological Features of COVID-19 in Northwest Russia in 20212021년 러시아 북서부 COVID-19의 역학적 특징Article Published on 2022-04-292022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] age Alpha Analysis assessment AT.1 variant base Beta carried changes in characteristic characterized China circulating Coronavirus infection COVID-19 COVID-19 incidence COVID-19 pandemic decrease Delta delta variant epidemiological epidemiological situation epidemiological surveillance Europe feature Federal District fluctuation fluctuations Genetic Genetic variant genetic variants global health globe Health highlight increase International Lineage lineages megacity morbidity mortality rate mortality rates Northwest Russia Novel coronavirus Novel coronavirus infection occurred omicron pandemic Pasteur Institute Phylogenetic Phylogenetic tree population density progression provided reached replaced Russia Saint Petersburg SARS-CoV-2 SARS-CoV-2 strains severe COVID-19 severity shown Spread strain Surveillance Transport vaccination variant variants variants of concern variants of concern. VoC Wuhan [DOI] 10.3390/v14050931 PMC 바로가기 [Article Type] Article
Benefits of integrated screening and vaccination for infection control감염관리를 위한 통합검진 및 예방접종의 장점Article Published on 2022-04-212022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] adverse outcome base Characteristics college Community compartmental model Compliance Coverage COVID-19 infections deaths delta variant develop disease disease spread disease transmission Diseases effective Effectiveness Efficacy Frequency Hospitalization hospitalizations hypothetical infection control Infectious diseases initial Intervention Model parameter predominant reduce Reproduction number reproduction numbers Safe Screening sensitivity analysis the vaccine Transmission vaccination vaccination rate Vaccination strategies Vaccine [DOI] 10.1371/journal.pone.0267388 PMC 바로가기 [Article Type] Article
Guide RNAs containing universal bases enable Cas9/Cas12a recognition of polymorphic sequences Research Published on 2022-03-252022-10-05 Journal: Nature Communications [Category] 변종, 유전자 메커니즘, 진단, 치료제, [키워드] applicability base bases canonical Cas9 complexes CRISPR degenerate DNA sequence Effects gene sequence Genetic guide guide RNA guide RNAs highlight HIV human gene Inclusion Organisms pathogen Polymorphisms preserved probe protease RNA sequence Single nucleotide polymorphism SNP SNPs spacer specificity variant variety while [DOI] 10.1038/s41467-022-29202-x [Article Type] Research
Structural Bases of Zoonotic and Zooanthroponotic Transmission of SARS-CoV-2SARS-COV-2의 동물성 및 동물원에서 Zooanthroponotic 전파의 구조적 염기Review Published on 2022-02-172022-09-10 Journal: Viruses [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, 조류인플루엔자, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analysed angiotensin angiotensin-converting enzyme 2 animal animals base coronavirus COVID-19 eradication focus foundation group highlight Host implication in vitro in vivo Interaction molecular persistence RBDs receptor Receptor binding domain receptor binding domains respiratory SARS-CoV-2 SARS-CoV-2 susceptibility severe acute respiratory syndrome Coronavirus Spike protein Spread susceptible the SARS-CoV-2 the spike protein Transmission variant virus zoonotic [DOI] 10.3390/v14020418 PMC 바로가기 [Article Type] Review
Sequence analysis for SNP detection and phylogenetic reconstruction of SARS-cov-2 isolated from Nigerian COVID-19 casesResearch article Published on 2022-01-012022-10-05 Journal: New Microbes and New Infections [Category] 변종, 유전자 메커니즘, 치료기술, [키워드] 2019-nCoV 3′UTR accounted addition Analysis average base causative pathogen characteristic characterized clade Clustering community transmission conserved Coronaviridae COVID-19 COVID-19 case Culture D614G D614G mutation disease distribution family Frequency GenBank genome sequence Genome sequence data genomic genomic region genus Betacoronavirus GISAID GISAID database highest include index case Intensive likelihood Lineage MAFFT morbidity and mortality Multiple mutants New coronavirus Nigeria Novel coronavirus ORF10 ORF1ab pandemic Phylogenetic Phylogenetic tree Phylogeny reference genome Region regions Result retrieved SARS-CoV-2 SARS-CoV-2 genome sequence severe respiratory symptom significantly higher similarity SNP SNPs spike gene Treatment Version viral sequences virus was done were used widespread [DOI] 10.1016/j.nmni.2022.100955 [Article Type] Research article
An Integrated Deep Learning and Belief Rule Base Intelligent System to Predict Survival of COVID-19 Patient under UncertaintyArticle Published on 2021-12-162022-10-31 Journal: Cognitive Computation [Category] COVID-19, [키워드] analyzed approach base belief Belief Rule Base COVID-19 COVID-19 patient Critical deep disease eight form globe Health learning outbreak Patient patient data patients Probability probability of survival reliability required Research risk factor rule survival System tested transfer learning Transmission Uncertainty Validation Accuracy VGG Net virus with COVID-19 X-ray [DOI] 10.1007/s12559-021-09978-8 PMC 바로가기 [Article Type] Article