Longitudinal Metabolomics Reveals Ornithine Cycle Dysregulation Correlates With Inflammation and Coagulation in COVID-19 Severe PatientsMicrobiology Published on 2021-12-032022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] amino acid metabolism amino acids analyzed association biochemical Biochemical parameters Blood change Coagulation correlated COVID-19 COVID-19 patient COVID-19 patients creating cycle cytokine Cytokines diagnostic dipeptides discharge Disease progression drug dysregulation FIVE global pandemic humans Inflammation longitudinal longitudinal change marker metabolic disorder metabolic factor metabolite metabolites metabolome metabolomic metabolomics Mild nine ornithine ornithine cycle pathogenic mechanisms pathogenicity peptides potential mechanism provided SARS-CoV-2 SARS-COV-2 infection serum severe disease Severe patient severe patients significantly significantly higher valuable resource [DOI] 10.3389/fmicb.2021.723818 PMC 바로가기 [Article Type] Microbiology
Biochemical role of serum ferratin and d-dimer parameters in COVID 19 diagnosisReview article Published on 2021-12-012022-10-05 Journal: Saudi Journal of Biological Sciences [Category] 바이오마커, [키워드] affected Anticoagulant Biochemical parameters Biomarker Blood C-reactive protein can be used clinical symptom clinical trials Coronavirus 2019 COVID 19 COVID-19 COVID-19 infection COVID-19 patient COVID-19 vaccine COVID19 Cytokine storm D-dimer diagnosed diagnosing Diagnosis disease effective Effects Efficacy elevated ferritin level humans identify immune response immunosuppressive Infection instances mandatory Mild moderate Mortality Numerous pandemic parameter Patient polymerase chain pro-inflammatory pulmonary real time reverse transcription risk RT-PCR SARS-CoV-2 serum Serum ferritin severe COVID-19 severity shown symptomatic disease the disease the patient vitamin D levels [DOI] 10.1016/j.sjbs.2021.08.040 [Article Type] Review article
Effect of IL-6, IL-8/CXCL8, IP-10/CXCL 10 levels on the severity in COVID 19 infectionIL-6, IL-8/CXCL8, IP-10/CXCL 10 수준이 COVID 19 감염의 중증도에 미치는 영향Article Published on 2021-12-012022-09-11 Journal: International journal of clinical practice [Category] MERS, SARS, 바이오마커, [키워드] affected albumin biochemical parameter Biochemical parameters Biomarkers correlation COVID 19 COVID 19 patients COVID-19 patient COVID-19 patients CRP CXCL10 CXCL8 D-dimer dimer disease Effect examined group groups healthy volunteer healthy volunteers highest IL-6 IL-6 level IL-6 levels IL-8 IL6 Infection IP-10 IP10 Laboratory marker MERS parameter Patient PCT positive correlation predict Prognosis prognostic indicator progression Protein SARS-COV-2 infection SARS-CoV-2 infections sedimentation serum Severe patient severity significantly statistical analysis statistically significant difference the disease the healthy total protein Volunteer WBC were assessed [DOI] 10.1111/ijcp.14970 PMC 바로가기 [Article Type] Article
Therapeutic interventions of remdesivir in diabetic and nondiabetic COVID-19 patients: A prospective observational study conducted on Pakistani population당뇨병 및 비당뇨병 COVID-19 환자에 대한 렘데시비르의 치료적 개입: 파키스탄 인구를 대상으로 수행된 전향적 관찰 연구Observational Study Published on 2021-12-012022-09-11 Journal: Journal of medical virology [Category] 임상, 치료제, [키워드] 95% confidence interval Administered administration biochemical parameter Biochemical parameters C-reactive protein Clinical improvement Complication conducted coronavirus disease COVID-19 COVID-19 infection COVID-19 patient D-dimer diabetes Diabetes Mellitus Diabetic diabetic patient diabetic patients dimer Effectiveness exhibited ferritin indicated individual Infection Intervention Lactate lactate dehydrogenase nondiabetic patients Novel coronavirus novel coronavirus disease Patient patients prospective observational study recruited Remdesivir Severe infection therapeutic therapeutic agent Treatment with COVID-19 [DOI] 10.1002/jmv.27256 PMC 바로가기 [Article Type] Observational Study
COVID-19 Autopsy in India: Protocols, Procedures, and ExperiencesPathology Published on 2021-10-222022-10-31 Journal: Cureus [Category] COVID-19, [키워드] - autopsy protocol in covid-19 deaths approved Autopsy autopsy in infected case Biochemical parameters changes in clinical collected Comorbidities Comorbidity Complete condition conducted Conducting Coronavirus disease 2019 correlated covid autopsy in developing nation COVID-19 covid-19 autopsy covid-19 sample collection from autopsy described died duration of hospitalization ethics committee experience Health help histopathological histopathological examination Infection limit mechanical ventilation methodology of covid-19 autopsy organ organs pathologic feature pathophysiology Patient polymerase chain positive Post-mortem post-mortem on covid-19 deaths Precaution precautions in covid-19 autopsy protocol provide ranged RT-PCR SARS-CoV-2 Spread the disease tissue tissues viral infection was performed was tested [DOI] 10.7759/cureus.18984 PMC 바로가기 [Article Type] Pathology
The lockdown effects on a pediatric obese population in the COVID-19 eraResearch Published on 2021-10-182022-10-29 Journal: Italian Journal of Pediatrics [Category] Coronavirus, MERS, SARS, [키워드] absence addition biochemical biochemical parameter Biochemical parameters BMI categories changes in children cholesterol clinic consequence Consequences correlation COVID-19 COVID-19 pandemic Effect evaluated feature glycemia greater HDL information Italy Laboratory LDL lockdown Messina obese parent parental Patient pediatric Pediatric patient Perspective physical activity Result risk Safe significant differences social distancing transaminases Triglyceride worsening [DOI] 10.1186/s13052-021-01142-0 PMC 바로가기 [Article Type] Research
Effect of Vitamin D Supplementation on Muscle Status in Old Patients Recovering from COVID-19 InfectionCOVID-19 감염에서 회복 중인 노인 환자의 근육 상태에 대한 비타민 D 보충제의 효과Randomized Controlled Trial Published on 2021-10-092022-09-12 Journal: Medicina [Category] MERS, SARS, 임상, 진단, [키워드] 6MWT addition Alanine alanine aminotransferase Aldolase aspartate Aspartate aminotransferase biochemical parameter Biochemical parameters Biochemistry blood count carried center cholecalciferol conducted contribute cortisol COVID-19 creatine creatine kinase damage decrease decreases double-blind trial Effect Elderly patient elderly patients exercise Glucose health center Health status hematological homeostasis hormone Improvements Infection involved Lactate lactate dehydrogenase life material men metabolism muscle Myoglobin objective pathology Patient physical physical fitness pilot study Placebo protective role Protein Quality of life reported Respiratory function Respiratory function tests Result returned SARS-CoV-2 serum spirometry status suffered Testosterone total protein transaminase two group two groups urea uric acid Vitamin Vitamin D Vitamin D supplementation was used [DOI] 10.3390/medicina57101079 PMC 바로가기 [Article Type] Randomized Controlled Trial
Temporal Associations of the SARS-CoV-2 NP Antigen and Anti-Spike Total Ig Levels with Laboratory Parameters in a Greek Cohort of Hospitalized COVID-19 Patients입원한 COVID-19 환자의 그리스 코호트에서 실험실 매개변수와 SARS-CoV-2 NP 항원 및 항스파이크 총 Ig 수준의 시간적 연관성Research Article Published on 2021-09-202022-09-10 Journal: Canadian Respiratory Journal [Category] MERS, SARS, 치료법, [키워드] anti-S antibody Antigen ARDS Assessing association biochemical parameter Biochemical parameters correlation COVID-19 COVID-19 patient COVID-19 severity develop enrolled evaluated females group Hospitalization hospitalized patient hospitalized patients Immunoglobulin investigated Laboratory laboratory parameter lateral flow Level lung Lungs males marker median age median time nucleocapsid protein Patient patients with pneumonia Pneumonia poor prognosis profile Protein repeated Result risk factor SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 nucleocapsid severe COVID-19 severe COVID-19 patients significant negative correlation specific antibodies spike symptom onset Temporal the SARS-CoV-2 therapeutic interventions Total total Ig [DOI] 10.1155/2021/6590528 PMC 바로가기 [Article Type] Research Article
Kabasura Kudineer (KSK), a poly-herbal Siddha medicine, reduced SARS-CoV-2 viral load in asymptomatic COVID-19 individuals as compared to vitamin C and zinc supplementation: findings from a prospective, exploratory, open-labeled, comparative, randomized controlled trial, Tamil Nadu, IndiaRandomized Controlled Trial Published on 2021-09-152022-10-04 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 95% CI adverse effect adverse event age Asymptomatic Asymptomatic COVID-19 Asymptomatic COVID-19 cases AYUSH Biochemical parameters changes in Chennai clinical clinical examination clinical presentation clinical symptom co-morbidities conducted control group coronavirus disease COVID COVID-19 COVID-19 cases Ct value declined drug Efficacy effort exploratory groups IFNγ IL-10 IL-2 IL-6 Immunity in both groups India individual interferon gamma Kabasura kudineer marker Necrosis no significant difference observé Occurrence Polyherbal decoction polymerase chain Primary outcome progressed progression Randomized Randomized controlled trial randomized, controlled trial recruited reduced reducing reduction in registry Result SARS-CoV-2 viral load Secondary outcomes Siddha Siddha Medicine significantly single-center Standard of care statistical analysis symptomatic t -test the disease the SARS-CoV-2 the study group threshold TNF α Traditional medicine Trial Vaccine Viral load Vitamin C was used [DOI] 10.1186/s13063-021-05583-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Is haem the real target of COVID-19?햄이 코로나19의 진짜 표적인가?Article Published on 2021-09-012022-09-11 Journal: Photodiagnosis and photodynamic therapy [Category] SARS, 변종, [키워드] ACE2 antiviral response approach approaches attack binding biochemical parameter Biochemical parameters Blood blood cell CD147 CD26 Cell changes in Clinical effect complex COVID-19 COVID-19 pandemic decrease decreases DGCR8 DGCR8-DROSHA Drosha erythrocyte erythrocytes Haem Haemoglobin HO-1 hypothesised Increases increases in induce interact involved iron Iron metabolism mechanism mechanism of action metabolism miRNA molecular docking Molecular docking study occur pathogenicity PDT precursor Prevent receptor reduce reported SARS-CoV-2 Serum ferritin the disease vaccination variant virulence virus [DOI] 10.1016/j.pdpdt.2021.102381 PMC 바로가기 [Article Type] Article