Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancerArticle Published on 2021-06-212022-10-04 Journal: Cell Death & Disease [Category] 바이오마커, [키워드] activated addition Analysis Antigen applied approach biological fluid Biomarker Cancer clinical setting clinically Cohort Diagnosis diagnostic procedure differentially expressed Endpoint ERG EVs extracellular vesicle feasibility Follow-up IMPROVE information marker men molecular test pathway Patient patients PD-L1 Predictive profile prognostic Prostate cancer Protein Protein-protein interaction networks proteomic Retrospective analysis robust sera Signaling survivin TGF-β translational Tumour biomarkers Vesicle [DOI] 10.1038/s41419-021-03909-z PMC 바로가기 [Article Type] Article
Semen impairment and occurrence of SARS-CoV-2 virus in semen after recovery from COVID-19COVID-19 회복 후 정액 손상 및 정액 내 SARS-CoV-2 바이러스 발생Article Published on 2021-05-172022-09-11 Journal: Human reproduction (Oxford, England) [Category] SARS, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered affected age all subjects Analysis azoospermia biological fluid caution chance collected Contagion coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity cross-sectional cross-sectional study demonstrated ELISA enrolled evaluated Fertility form function General population healing Health Organization IL-8 impairment implication index Infection interleukin interleukin-8 leukocyte leukocytes limit men Nasopharyngeal swab Occurrence oligo-crypto-azoospermia parameter Participants Patient performed positive quantification Questionnaires registration number reproductive routine RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 infections SARS-CoV-2 virus SARS-CoV2 Semen Semen analysis severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 sexual sexual transmission significantly specimen Statistical power tested the SARS-CoV-2 genome Urine virus virus RNA was performed World Health Organization [DOI] 10.1093/humrep/deab026 PMC 바로가기 [Article Type] Article
Seasonal Stability of SARS-CoV-2 in Biological FluidsArticle Published on 2021-04-302022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Aerosols Biological biological fluid biological fluids Blood breast milk close contact condition conditions contaminated surfaces droplets environmental condition fomite half-life Human humans implication nasal occur potential risk remained Saliva SARS-CoV-2 SARS-CoV-2 stability SARS-CoV-2 transmission seasonal secreted significantly sputum stability surface survived transmission of SARS-CoV-2 Urine virus virus stability [DOI] 10.3390/pathogens10050540 PMC 바로가기 [Article Type] Article
Monitoring COVID-19 Transmission Risks by Quantitative Real-Time PCR Tracing of Droplets in Hospital and Living EnvironmentsResearch Article Published on 2021-01-062022-10-30 Journal: mSphere [Category] COVID-19, MERS, [키워드] accumulated acute respiratory syndrome amplicons association Asymptomatic carriers biofluid biological fluid biological fluids collected communicable disease Contamination coronavirus coronavirus disease COVID COVID-19 creating Critical droplet droplets Environment environmental contamination evaluated fecal fomite highest hospital hospital ward identify infections Influenza marker microbiota monitoring multiplex nasopharyngeal NGS occur pandemic Patient patients PCR public health qPCR quantitative real-time PCR released risk Saliva SARS-CoV-2 searched secretion selected Sequencing significantly Spread Support surface swabs trace tracing Transmission Viral RNA virus was performed widespread [DOI] 10.1128/mSphere.01070-20 PMC 바로가기 [Article Type] Research Article
Incidence and Persistence of Viral Shedding in COVID-19 Post-acute Patients With Negativized Pharyngeal Swab: A Systematic ReviewMedicine Published on 2020-08-282022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Analysis biological fluid Blood blood sample caused Community coronavirus coronavirus disease COVID-19 criteria diffusion droplets epidemiological Factor feature fecal Limited log rank test Mann–Whitney U -test median occur Patient patients patients with COVID-19 post-acute phase protocol Registered respiratory tract review RT-PCR SARS-CoV-2 SARS-CoV-2 viral RNA shedding significantly specimen specimens Spread statistical analysis Stool subgroup analysis Swab swabs Transmission Urine viral RNA clearance viral shedding [DOI] 10.3389/fmed.2020.00562 PMC 바로가기 [Article Type] Medicine
Nano-Vesicle (Mis)Communication in Senescence-Related PathologiesReview Published on 2020-08-262022-10-31 Journal: Cells [Category] Coronavirus, MERS, [키워드] aging apoptotic bodies biological fluid cells cellular senescence changes COVID-19 COVID-19 infections Critical death Diseases Exosome exosome biogenesis Exosomes extracellular vesicle Extracellular vesicles heterogeneous group homeostasis information involved Microvesicles miRNA multivesicular body nucleic acids organ physiological plasma Potential biomarker Probability Protein Saliva senescent Signaling Structure susceptibility Transport Urine Vesicle [DOI] 10.3390/cells9091974 PMC 바로가기 [Article Type] Review
Predicted peptide patterns from the SARS-CoV-2 proteome for MS-MS based diagnosisResearch Article Published on 2020-06-302022-10-28 Journal: Bioinformation [Category] COVID-19, [키워드] 2019 novel coronavirus Analysis biological fluid body fluid can be used caused complex COVID-19 dataset Diagnosis early diagnosis Health manifested nasopharyngeal swabs pandemic PCR peptide platform proteome SARS-CoV-2 SARS-CoV-2 peptides SARS-CoV-2 viral Skyline targeted proteomics the SARS-CoV-2 the WHO tryptic peptides Variability viral mutation virus [DOI] 10.6026/97320630016477 PMC 바로가기 [Article Type] Research Article
A Review of Salivary Diagnostics and Its Potential Implication in Detection of Covid-19Infectious Disease Published on 2020-04-172022-10-31 Journal: Cureus [Category] COVID-19, [키워드] aerosol-generating procedures antimicrobial effect asked biological fluid biological marker bleeding cause changes in clinical decision clinical monitoring close contact Community coronavirus disease Coronaviruses cost effective defined dentist detection develop development Diagnosis diagnostic diagnostics digestion Disease diagnosis functions greater Health Healthcare professional healthcare worker hospitalized patient hospitals IMPROVE involved nasopharyngeal nasopharyngeal specimen non invasive Non-invasive novel corona virus offer oropharyngeal swab outbreak pandemic Patient Patient care Potential produced Protein Pyrexia Rapid required Research respiratory symptoms respiratory virus respiratory viruses review risk of transmission Safe Saliva salivary salivary diagnostics salivary gland SARS-CoV secretion specimen systemic disease the patient utilised virus [DOI] 10.7759/cureus.7708 PMC 바로가기 [Article Type] Infectious Disease