blood cell – Page 2 – Communicable Diseases Research

Histidine-rich glycoprotein as a novel predictive biomarker of postoperative complications in intensive care unit patients: a prospective observational study

중환자실 환자의 수술 후 합병증에 대한 새로운 예측 바이오마커로서의 히스티딘이 풍부한 당단백질: 전향적 관찰 연구

Observational Study

Published on 2022-07-202022-09-11
Journal: BMC Anesthesiology
[Category] MERS, 바이오마커, 임상,

Alcohol Increases Lung Angiotensin-Converting Enzyme 2 Expression and Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Subunit 1-Induced Acute Lung Injury in K18-hACE2 Transgenic Mice

알코올은 폐 안지오텐신 전환 효소 2 발현을 증가시키고 중증 급성 호흡기 증후군을 악화시킨다

Article

Published on 2022-07-012022-09-11
Journal: The American journal of pathology
[Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] ACE2 Activation acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alcohol Alcohol Abuse alcohol consumption alveolar Alveolar space angiotensin angiotensin-converting enzyme 2 Biomarker blood cell body weight Bronchoalveolar lavage fluid chronic coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Course Cytokine storm decrease dramatic increase enzyme Ethanol Express Factor human ACE2 receptor Human angiotensin-converting enzyme 2 Immune cell immune cells increase Inflammasome Interaction K18-hACE2 lung tissue mechanism mice Mortality NF-κB NLR NLRP3 overexpression pandemic parenchymal proinflammatory protein 3 recruitment reported respiratory respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-CoV-2 spike protein severe acute respiratory syndrome Coronavirus spike Spike protein STAT3 Stress subunit syndrome therapeutic approach therapeutic approaches transgenic mice White blood cell worsening
[DOI] 10.1016/j.ajpath.2022.03.012 PMC 바로가기 [Article Type] Article

Early renal impairment is associated with in-hospital death of patients with COVID-19

조기 신장 장애는 COVID-19 환자의 병원 내 사망과 관련이 있습니다.

Article

Published on 2022-06-012022-09-11
Journal: The clinical respiratory journal
[Category] COVID19(2023년), SARS, 치료기술,

[키워드] Admission age ALB albumin Blood blood cell blood platelet BNP Brain brain natriuretic peptide C-reactive protein Clinical management clinical manifestation Clinical outcome Cohort cohorts collected Complication coronavirus disease Coronavirus disease 2019 count COVID-19 COVID-19 patient creatine CRP determine diabetes diagnosed with COVID-19 early renal impairment EGFR erythrocyte sedimentation erythrocyte sedimentation rate ESR higher risk Hospitalization Hospitalized impairment In-hospital death incidence independent risk factor independent risk factors Laboratory lymphocyte Lymphocyte count Mortality nitrogen Patient patients patients with COVID-19 peptide Pneumonia pneumonia. prealbumin prognostic Proteinuria Record renal renal function renal impairment renal insufficiency risk stratification sedimentation rate serum significantly higher significantly lower Stratification Urine WBC White blood cell
[DOI] 10.1111/crj.13496 PMC 바로가기 [Article Type] Article

Complete blood cells count abnormalities in COVID-19 patients and their prognostic significance: Single center study in Makkah, Saudi Arabia

전체 혈액 세포는 COVID-19 환자의 이상과 그 예후 중요성을 계산합니다: 사우디 아라비아 Makkah의 단일 센터 연구

Article

Published on 2022-06-012022-09-11
Journal: Saudi medical journal
[Category] COVID19(2023년), SARS, 치료기술,

[키워드] abnormality Admission age Anemia Blood blood cell blood count C-reactive protein clinical disease clinically Complete complete blood count coronavirus disease COVID-19 COVID-19 patient COVID-19 severity CRP Decision making decrease detectable disease effective intervention elevated evaluate feature female ferritin force group Inclusion Inflammation Inflammatory marker inflammatory markers leucocyte leucocytosis lymphopenia male management moderate N/L N/L ratio neutrophil neutrophil count neutrophilia non-survivor Non-survivors occurred Older age Organ failure outcome parameter Patient patients Peripheral blood Platelets platelets count prognostic prognostic significance. Rapid test regimen regimens Respiratory disease respiratory diseases Saudi Arabia security Serum ferritin Serum level Severe case severe COVID-19 disease severity Significant significant decrease significantly viral infection were excluded
[DOI] 10.15537/smj.2022.43.6.20210893 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Spike Protein Expression In Vitro and Hematologic Effects in Mice Vaccinated With AZD1222 (ChAdOx1 nCoV-19)

AZD1222(ChAdOx1 nCoV-19) 백신을 접종한 쥐의 시험관 내 SARS-CoV-2 스파이크 단백질 발현 및 혈액학적 효과

Article

Published on 2022-04-122022-09-11
Journal: Frontiers in Immunology
[Category] COVID19(2023년), SARS, 진단, 치료기술,

[키워드] Adenovirus Adenovirus-vectored vaccine AZD1222 AZD1222 (ChAdOx1 nCoV-19) blood cell cells ChAdOx1 ChAdOx1 nCoV-19 change cleavage cleaved COVID-19 COVID-19 vaccination COVID-19 vaccine detectable Disease progression Effect Evidence expected expression hematologic hematology parameter Hematology parameters host cell host cells Host immune response host immune responses immediate effect immediate effects immune responses immunization immunohistochemistry in vitro in vivo Infection innate immune response intramuscular intravenous investigated mice morbidity morbidity and mortality nCoV neutrophil occurred parameters plasma concentration Platelet platelet activation platelet and white blood cell parameters. produced promote Protein prothrombotic state Respiratory failure response risk S1 protein S1 subunit SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike glycoprotein SARS-CoV-2 spike protein sera severe COVID-19 spike spike glycoprotein Spike protein the S1 subunit undetectable vaccination vectored vaccine vehicle Viral Viral particles White blood cell
[DOI] 10.3389/fimmu.2022.836492 PMC 바로가기 [Article Type] Article

Definition of the Immune Parameters Related to COVID-19 Severity

COVID-19 심각도와 관련된 면역 매개변수의 정의

Article

Published on 2022-03-182022-09-11
Journal: Frontiers in Immunology
[Category] SARS, 치료기술,

[키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered Admission allocation among others Analysis analyzed Blood blood cell blood cell count caused Cell changes in clinical decision Clinical management Cohort coronavirus COVID-19 COVID-19 outcome COVID-19 patients Critical Cutoff defined Definition described disease disease severity fluctuations for inclusion granulocyte groups highlight Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients immunological immunological changes intensive care intensive care unit admission Laboratory Laboratory test lymphocyte Medical resources Mild moderate non-survivor offer outcome oxygen oxygen support Oxygen therapy parameter Patient Peripheral blood peripheral blood cell peripheral blood cells predict Predictive proof recorded ROC Curve sensitivity separated severe acute respiratory syndrome Coronavirus severity Severity of disease Severity Score specificity survival survivor symptomatic the disease therapy Triage triage.
[DOI] 10.3389/fimmu.2022.850846 PMC 바로가기 [Article Type] Article

Erythro-VLPs: Anchoring SARS-CoV-2 spike proteins in erythrocyte liposomes

Erythro-VLPS : 적혈구 리포좀에서 SARS-COV-2 스파이크 단백질을 고정시킨다

Research Article

Published on 2022-03-112022-09-10
Journal: PLoS ONE
[Category] MERS, SARS, 변종,

[키워드] ACE-2 acute respiratory syndrome acute respiratory syndrome coronavirus 2 Administered anchoring angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 assays average binding BLI Blood blood cell Cell coronavirus coronavirus disease COVID-19 cytoplasmic membrane defined dose-dependent Dynamics ELISA enzyme enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays facilitate fluorescent functional insertion intravenously Liposome membranes molecular dynamics novel open outer membrane pandemic Particles platform Protein protocol red blood cell respiratory S-protein SARS-CoV-2 spike SARS-CoV-2 spike protein scattering Seroconversion severe acute respiratory syndrome Coronavirus surfactant the SARS-CoV-2 therapeutic strategy Therapeutics Trial variants virus virus viruses was used
[DOI] 10.1371/journal.pone.0263671 PMC 바로가기 [Article Type] Research Article

Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Patients With COVID-19: An Italian Retrospective Study

COVID-19로 입원한 환자의 낮은 생존율에 대한 위험 요인으로 입원 시 낮은 비타민 D 상태: 이탈리아 후향적 연구

Article

Published on 2022-03-012022-09-11
Journal: Journal of the American Nutrition Association
[Category] MERS, SARS, 바이오마커,

[키워드] 25-hydroxyvitamin D 95% confidence interval Admission Alpha Analysis association available data best Biomarker blood cell C-reactive protein characteristic Clinical course Coagulation Cohort conducted consecutive patient count COVID-19 cytokine Cytokine storm D-dimer different time point evaluate exhibited Factor ferritin fibrinogen High-sensitivity C-reactive protein hospital Hospital mortality Hospitalization hospitalized patient hospitalized patients hsCRP hypovitaminosis Hypovitaminosis D IL-6 in-hospital mortality incidence independent risk factor Inflammation Inflammatory inflammatory markers institution interleukin interleukin 6 Italian logistic regression model lymphocyte marker median Mortality mortality. Multivariate analysis Necrosis neutrophil NLR non-survivor Non-survivors Odds ratio Patient PCT performed Poor poor prognosis Predictive preliminary findings Prevalence procalcitonin receiver operating characteristic Retrospective study risk SARS-CoV-2 SARS-COV-2 infection Sepsis serum serum 25-hydroxyvitamin D severity of COVID-19 significantly significantly higher status subsequent survivor the disease TNF-α Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha two groups Vitamin Vitamin D Vitamin D status WBC WBC count White blood cell with COVID-19
[DOI] 10.1080/07315724.2021.1877580 PMC 바로가기 [Article Type] Article

Innate immune response analysis in COVID-19 and kawasaki disease reveals MIS-C predictors

COVID-19 및 가와사키병의 타고난 면역 반응 분석은 MIS-C 예측 인자를 밝힙니다

Article

Published on 2022-03-012022-09-11
Journal: Journal of the Formosan Medical Association = Taiw
[Category] SARS, 변종, 치료기술,

[키워드] acute SARS-CoV-2 infection Adults analyses Analysis ArrayExpress association Blood blood cell Blood cells CASP1 CD14 CD36 children Cohort correlated COVID-19 COVID-19 diagnosis COVID-19 severity dataset determine disease downloaded dysregulated dysregulation enriched pathway enriched pathways expression level FCGR2A gene expression signature genetic polymorphisms HLA-DOB IFI16 IFNAR1 immune dysregulation immune response immune responses increased expression Inflammatory Innate innate immune innate immune gene innate immune genes innate immune response Innate immunity Interaction interactions irak4 IRF3 Kawasaki disease MIS-C moderate multisystem inflammatory syndrome. network network analysis NLRP3 pathway Patient PELI1 polymorphism predict predictor predisposition Pycard reveal SARS-CoV-2 infections severe COVID-19 severity STAT3 STING susceptibility syndrome TLR2 TLR7 TLR8 Transcriptome transcriptome datasets transcriptomes variant variants was used with COVID-19
[DOI] 10.1016/j.jfma.2021.06.009 PMC 바로가기 [Article Type] Article

Persistence of SARS-CoV-2 total immunoglobulins in a series of convalescent plasma and blood donors

일련의 회복기 혈장 및 헌혈자에서 SARS-COV-2 총 면역 글로불린의 지속성

Research Article

Published on 2022-02-242022-09-10
Journal: PLoS ONE
[Category] COVID19(2023년), MERS, SARS, 진단, 치료법,

[키워드] age analysed Analysis anti-SARS-CoV-2 antibodies antibody antibody waning Asymptomatic automated average average age Blood blood cell blood cell count blood cell counts blood donation blood donor Blood Group chemiluminescence immunoassay Concentration Contagion convalescent plasma COVID-19 COVID-19 case decay determine develop Donor donors evaluated feature first positive Follow-up follow-up period help human serum Immunity Immunoglobulin individual Infection Lower lymphocyte Lymphocyte count maintain majority male material median time minimum MOST N protein neutrophil Neutrophils nucleocapsid protein optical optical density outcome percentage percentages Peripheral blood plasma positive predict Protein Quantitative recognizing Relapse remained Result SARS-CoV-2 Sex symptomatic and asymptomatic total antibodies total antibody vaccination was performed Whole blood
[DOI] 10.1371/journal.pone.0264124 PMC 바로가기 [Article Type] Research Article