Endothelial cell infection and dysfunction, immune activation in severe COVID-19
내피 세포 감염 및 기능 장애, 심한 Covid-19에서의 면역 활성화
Research Paper
[키워드] Activation
adhesion
alveolar septa
animals
body weight
Body weight loss
Brain infection
cadherin
cause
Cell
circulation
Coagulation
collected
complement
conducted
contribute
correlated
COVID-19
COVID-19 disease
COVID-19 patients
cytokine
Deceased
develop
downregulation
dysfunction
edema
electron microscopy
endothelial
Endothelial cell
endothelial cells
Endotheliitis
Eosinopenia
epithelial cells
evidenced
fatality
hemorrhage
ICAM1
immune activation
Immune cell
immune cells
immunostaining
infect
Infection
initial
Injury
interstitial inflammation
K18
K18-hACE2
lung
Lung epithelial cells
Lungs
lymphocytopenia
mice
Microscopy
NHP
NHP models
organ
organs
Pathogenesis
pathway
Pathways
Patient
perivascular inflammation
Platelet
Platelets
Pneumonia
pulmonary
PULMONARY VESSELS
rationale
Result
RNA-seq analyses
SARS-CoV-2
SARS-COV-2 infection
serum
severe COVID-19
severe COVID-19 disease
severity
Signaling
Single Cell
up-regulation
upregulated
Vascular
VCAM1
VE-cadherin
vessel
weight loss
while
[DOI] 10.7150/thno.61810 PMC 바로가기 [Article Type] Research Paper
[DOI] 10.7150/thno.61810 PMC 바로가기 [Article Type] Research Paper