Caenorhabditis elegans – Page 2 – Communicable Diseases Research

Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine

스트레스 반응 및 대사 유전자 조절은 낮은 S-아데노실메티오닌에서 변경됩니다.

Research Article

Published on 2018-11-282022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

Non-proteolytic activity of 19S proteasome subunit RPT-6 regulates GATA transcription during response to infection

19S proteasome subunit RPT-6의 비 단백질 분해 활성은 감염에 대한 반응 동안 GATA 전사를 조절합니다

Research Article

Published on 2018-09-282022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] activated affected ATPase Bacterial infection Bacterial infections binding Caenorhabditis elegan Caenorhabditis elegans component conserved Defense domain Evidence expression expression of gene GATA GATA transcription factor GATA transcription factors Gene Expression Genes immune function immune functions immune gene immune genes immune response Immunity in vivo independent independent of indicated Infection interact Interaction involved oxidative stress pathogen physically proteasome proteolytic activity Pseudomonas aeruginosa regulate Regulation required subunit Transcription transcription factor transcription factors
[DOI] 10.1371/journal.pgen.1007693 PMC 바로가기 [Article Type] Research Article

Viable-but-Nonculturable Listeria monocytogenes and Salmonella enterica Serovar Thompson Induced by Chlorine Stress Remain Infectious

염소 스트레스로 유도된 생존 가능하지만 배양 불가능한 리스테리아 모노사이토제네스와 살모넬라 엔테리카 세로바 톰슨은 감염성을 유지한다.

Research Article

Published on 2018-04-172024-07-29
Journal: mBio [Category] 살모넬라증,

[키워드] Caenorhabditis elegans food-borne pathogens Listeria Salmonella VBNC
[DOI] 10.1128/mBio.00540-18 PMC 바로가기 [Article Type] Research Article

A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa

녹농균에 대한 방어를 위해서는 보존된 미토콘드리아 감시 경로가 필요합니다

Research Article

Published on 2017-06-292022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] activate activated Activation addition Bacterial battery Caenorhabditis Caenorhabditis elegans Cell cellular structure conserved Critical cytological damage Defense defense mechanisms described Diseases dysfunction Effect elegan elegans element Ethanol expand exposure to family functions genetics Health heat homeostasis Host host defense human pathogen hypothermia hypoxia Imbalance immune responses include increasingly indicate Infection innate immune response Innate immunity Interaction intestinal kill leads liquid mammals mechanism mechanisms mitigate mitochondrial organelle organism Organisms overlap overlapping oxidative damage P . aeruginosa pathogen Pathogens pathway Physiology Prevent Protein Pseudomonas aeruginosa pyoverdine recognizing Regulation required respond response secreted selective shown Stress stress response Surveillance threat Toxicity transcriptomics unique upregulation variety virulence
[DOI] 10.1371/journal.pgen.1006876 PMC 바로가기 [Article Type] Research Article

Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes

다른 동일한 tRNA 유전자의 조직 및 시간 특이적 발현

Research Article

Published on 2016-08-252022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] abrogate adaptive addition Affect affected age aggregation Amino acid Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans can not changes in codon codon usage conserved disease Diseases dynamic eight element expressed expression expression level expression levels fluorescent Genes genome-wide analysis GFP hallmark Host identity intrinsic intron Intronic introns lead MONITOR mutations nematodes neurodegeneration observation orthologous gene orthologous genes Pairing predict promoter promoters Protein Protein misfolding protein sequences protein translation protein-coding gene protein-coding genes recognize regulated Regulating reporter ribosome sequence synonymous tissue tissues transcribed tRNA tRNAs Tryptophan
[DOI] 10.1371/journal.pgen.1006264 PMC 바로가기 [Article Type] Research Article

Comparative Genomic Analysis of Drechmeria coniospora Reveals Core and Specific Genetic Requirements for Fungal Endoparasitism of Nematodes

Drechmeria coniospora의 비교 게놈 분석을 통해 선충류의 곰팡이 내부 기생충에 대한 핵심 및 특정 유전적 요구 사항이 밝혀졌습니다.

Research Article

Published on 2016-05-062022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] acquisition adhesion Analysis arms race branch Caenorhabditis elegan Caenorhabditis elegans can be used characterisation characterized Comparative core Dissection elegan elegans Endoparasitism Evolution evolutionary arms race expresse expressed fluorescent reporter genes functional fungal Fungal infection fungi fungus Gene Expression Gene expression analysis gene families gene family Genes Genetic genetic engineering genetic transformation Genome genomic growth Host in silico infect Infection initial Interaction Interference involved kill killing knock-out knowledge lifecycle mechanism Modification molecular mycelia nematode nematodes NETs opens parasitic nematodes parasitism pathogen pathogen’ Phylogenetic analysis probe regulated reported reporter genes Requirement sequenced Specific spore Stage Tolypocladium transformation TRAP virulence
[DOI] 10.1371/journal.pgen.1006017 PMC 바로가기 [Article Type] Research Article

The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones

Caenorhabditis elegans 단백질 FIC-1은 Heat-Shock 70 계열 단백질, 번역 연장 인자 및 히스톤을 공유적으로 수정하는 AMPylase입니다

Research Article

Published on 2016-05-032022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] approach ATP bacterial pathogen biochemical Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans connection consequence conserved core histone domain elegan elegans elongation elongation factors Endoplasmic reticulum Factor Factors family family members functional Heat shock heat shock protein heat-shock protein histone identify in vitro in vivo innate immune response Innate immunity modify novel nuclear ortholog P . aeruginosa pathogen phenotype post-translational modification Previous studies previous study Protein Proteins Pseudomonas aeruginosa sequence identity substrate susceptibility target protein target proteins three-dimensional structure translation unfolded protein response UPR
[DOI] 10.1371/journal.pgen.1006023 PMC 바로가기 [Article Type] Research Article

Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food‐borne bacterial pathogens

저철분 식이 섭취는 식품 유래 세균 병원체에 의한 장 감염의 장내 염증 반응과 병리학을 억제합니다.

journal-article

Published on 2015-09-012024-07-30
Journal: Neurogastroenterology and motility : the official [Category] 살모넬라증,

[키워드] Caenorhabditis elegans gut microbiome intestinal pathogens iron supplementation lipocalin-2.
[DOI] 10.1002/eji.201545642 [Article Type] journal-article

Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans

Caenorhabditis elegans의 소포 수송에 의한 세포 간 프리온 도메인의 확산

Research Article

Published on 2013-03-282022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] aggregate aggregation ALS amyloid Amyotrophic lateral sclerosis animal model appearance asparagine Author autonomous autophagy Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans Cell cellular cellular pathway conformation culture cell cytosolic Degradation developmental delay different disease Diseases domain elegan embryonic Encephalopathy Epigenetic Evidence exhibit expressed expressing expression form Glutamine hallmark hallmarks include infect infectious Lateral Sclerosis lobar lysosomal lysosomal vesicle mechanism misfolded protein misfolded proteins mitochondrial multicellular multicellular organism N-terminus naive cells neurodegenerative neurodegenerative disorders NM organism Parkinson's Disease pathology pathway prion Propagation Protein Proteins real time recent Spread spreading thought tissue tissue culture tissues Toxicity trait transgenic mice transmissible spongiform encephalopathies Transmission Transport underlie Vesicle vesicular widespread yeast
[DOI] 10.1371/journal.pgen.1003351 PMC 바로가기 [Article Type] Research Article

The GATA Transcription Factor egl-27 Delays Aging by Promoting Stress Resistance in Caenorhabditis elegans

GATA 전사 인자 egl-27은 꼬마선충의 스트레스 저항성을 촉진하여 노화를 지연시킵니다

Research Article

Published on 2012-12-132022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] accumulated activated Affect age aging aging process alteration animals Author Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans conserved daf-16 Delay Effect elegan expression Factor Factors found FoxO GATA GATA transcription factor Gene Genes heat stress identify IGF-1 impair IMPROVE increase inhibited insulin Intersection involved limit Longevity molecular mechanism molecular mechanisms mutant overexpression oxidative stress pathway Pathways promote Promoting PROTECT protective response protective responses receptor reduced required resistance response Signaling significantly Stress stress response stress responses suppresse survival target transcription factor wild-type worm worms
[DOI] 10.1371/journal.pgen.1003108 PMC 바로가기 [Article Type] Research Article