Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia
Article
[키워드] affected
alteration
anti-inflammatory cytokines
both groups
CD4
CD4-positive T cells
CD57
CD8
cells
central memory
chemokine
chemokine receptors
condition
COVID-19
COVID-19 patient
cytokine production
Cytokines
effector memory
flow cytometry
healthy controls
IL-17
immune system
immunological
Immunological memory
interferon-γ
Italy
less
lymphocyte
Lymphocyte differentiation
naïve
Necrosis
observation
pandemic
pathophysiological
Patient
patients with COVID-19
PD1
Peripheral blood
Pneumonia
proinflammatory
proliferate
public health
Regulatory T cell
required
SARS-CoV-2
Significant
significant increase
T cell
T cell activation
T cells
T helper
terminally differentiated
therapeutic strategy
TNF
transcription factor
viral infection
[DOI] 10.1038/s41467-020-17292-4 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41467-020-17292-4 PMC 바로가기 [Article Type] Article