Anti-Arbovirus Antibodies Cross-React With Severe Acute Respiratory Syndrome Coronavirus 2Article Published on 2022-12-212023-07-10 Journal: Microbiology Spectrum [Category] COVID19(2023년), [키워드] arbovirus Chikungunya virus cross-protection dengue virus Neutralizing antibodies SARS-CoV-2 serological cross-reactivity. [DOI] 10.1128/spectrum.02639-22 PMC 바로가기
A Brighton Collaboration standardized template with key considerations for a benefit/risk assessment for an inactivated viral vaccine against Chikungunya virusChikungunya 바이러스에 대한 비활성화된 바이러스 백신의 이점/위험 평가에 대한 주요 고려 사항이 포함된 Brighton Collaboration 표준화 템플릿Clinical Trial Published on 2022-08-192022-09-12 Journal: Vaccine [Category] MERS, 비임상, 임상, 진단, [키워드] assessment benefit Benefit/Risk Chikungunya Chikungunya virus clinical study clinical trials collaboration COVID-19 database disease effective emerging disease evaluated Extensive feature flexible group Health Human humoral immune responses inactivated inactivation India key consideration Nile pandemic participant Phase I poliomyelitis preclinical study profiles provide risk river Safety Seasonal influenza subjects Vaccine vaccine platform Vaccines Vero Cell virus West working [DOI] 10.1016/j.vaccine.2022.06.006 PMC 바로가기 [Article Type] Clinical Trial
Bomidin: An Optimized Antimicrobial Peptide With Broad Antiviral Activity Against Enveloped VirusesBomidin: 외피 바이러스에 대한 광범위한 항바이러스 활성을 가진 최적화된 항균 펩티드Article Published on 2022-05-192022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Against AMP AMPs antibiotic antimicrobial antimicrobial peptide antimicrobial peptide. antimicrobial peptides AVP Bacteria Bacterial bovine Chikungunya Chikungunya virus CHIKV Coronavirus-2 Defense Dengue dengue virus DENV-2 disrupt Escherichia coli Evolution expressed expression extraction front line fungi global public health herpes simplex herpes simplex virus heterologous expression HSV-2 life-threatening lipids mechanism membrane membranes methionine molecular offer organism overcome pathogen Pathogens peptide peptides produced purification Research SARS-CoV-2 sequence Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus therapeutic variety virus viruses [DOI] 10.3389/fimmu.2022.851642 PMC 바로가기 [Article Type] Article
Intracellular mono-ADP-ribosyltransferases at the host–virus interphaseReview Published on 2022-05-102023-08-30 Journal: Cellular and Molecular Life Sciences [Category] E형 간염, [키워드] ADP-ribosylation alphavirus Chikungunya virus coronavirus hydrolase interferon macrodomain MARylation PARP Pattern recognition receptors Signaling [DOI] 10.1007/s00018-022-04290-6 PMC 바로가기 [Article Type] Review
Plant-Derived Recombinant Vaccines against Zoonotic VirusesReview Published on 2022-01-212022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] approach candidate vaccine Chikungunya virus chimeric Crimean–Congo hemorrhagic fever virus current deaths dengue virus disease Diseases Ebola virus effective emerging coronaviruses expression genetic material Hantaviruses Henipaviruses hepatitis E virus HIV Human immunogenic include lack Newcastle virus offer organization plant plant molecular farming Prevent produced Proteins Rabies virus recombinant Recombinant protein recombinant vaccines restrict Safe Spread structural proteins subunit vaccination Vaccine Vaccines viral peptides virion virus virus particles Virus-like particle virus-like particles viruses VLP VLPs West Nile Virus yellow fever virus Zika virus zoonotic zoonotic disease zoonotic influenza Zoonotic viruses [DOI] 10.3390/life12020156 PMC 바로가기 [Article Type] Review
Potential Benefits of Antiviral African Medicinal Plants in the Management of Viral Infections: Systematic ReviewPharmacology Published on 2021-12-242022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] activity Africa African Antiviral antiviral activity astrovirus candidate Canine distemper Chikungunya virus clinical trial Coronavirus disease 2019 COVID-19 database demonstrated Dengue Ebola virus echovirus enterovirus Evidence Fever Google Google Scholar herbal mecidine HIV Human human diseases in vitro in vivo management measles virus medicinal plants Outbreaks pandemic Parvovirus plant plants Potential provided required respiratory review Rift SARS-CoV-2 SARS-CoV-2 (2019-nCoV) screened searched sensitivity Treatment Valley vesicular stomatitis Viral diseases viral infection viral infections virus yellow fever Zika virus [DOI] 10.3389/fphar.2021.682794 PMC 바로가기 [Article Type] Pharmacology
A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virusArticle Published on 2021-12-092022-10-04 Journal: Nature Medicine [Category] 비임상, 임상, 치료제, [키워드] Administered Adverse antibody approved arthralgia Arthritis cause characterized Chikungunya virus clinical trial Concentration conducted detectable disease dose dose-dependent Effect evaluate evaluated Ex vivo expression Fever functional healthy Human IgG IgG level immunocompromised individual Immunoglobulin in vivo Infant Infection Infectious diseases interim analysis intravenous knowledge Messenger RNA Mild moderate monoclonal monoclonal antibody mRNA mRNA-based Neutralizing Neutralizing activity neutralizing antibody offer participant patients phase 1 trial Placebo placebo-controlled plasma concentration predicted Preventive medicine Primary outcome Randomized Rash serum severity single dose therapeutic therapeutic use therapy Tolerability Treatment Trial viral infection [DOI] 10.1038/s41591-021-01573-6 PMC 바로가기 [Article Type] Article
Overview on Chikungunya Virus Infection: From Epidemiology to State-of-the-Art Experimental ModelsReview Published on 2021-10-052023-08-30 Journal: Frontiers in Microbiology [Category] E형 간염, [키워드] in vitro cell model cell entry Chikungunya virus Epidemiology non-human primate models Pathogenesis replicative cycle rodent models [DOI] 10.3389/fmicb.2021.744164 PMC 바로가기 [Article Type] Review
A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trialArticle Published on 2021-07-302022-10-04 Journal: Nature Communications [Category] 임상, [키워드] adenovirus vectored vaccine adverse event alphaviruses antigens capsid cause caused cellular ChAdOx1 Chikungunya Chikungunya virus clinical trial dosage dose Dose escalation expressing full-length healthy volunteer humoral IgG immunogenicity data induce infected individuals Intramuscular injection Lineage lineages Major majority Mild moderate neutralizing antibody nonrandomized Open-label outbreak Outbreaks Outcomes research participant phase 1 trial polyprotein PRNT recruited Region reported Safe serious adverse reaction Seroconversion single dose T-cell Response tested Tolerability Trial vaccination Vaccine Vaccines viral infection virus [DOI] 10.1038/s41467-021-24906-y PMC 바로가기 [Article Type] Article
Serological cross-reactivity using a SARS-CoV-2 ELISA test in acute Zika virus infection, Colombia콜롬비아 급성 지카바이러스 감염에서 SARS-CoV-2 ELISA 검사를 이용한 혈청학적 교차반응Article Published on 2020-12-012022-09-12 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, [키워드] arbovirus Arbovirus infection Asymptomatic Chikungunya virus collected Contact COVID-19 cross-reactivity Dengue dengue virus diagnosed Diagnosis endemic area endemic diseases evaluate Fever group individual individuals Infection investigated Patient SARS-CoV-2 SARS-CoV-2 ELISA sera serological serological cross-reaction Seronegativity Serosurvey Symptom validation validation study Zika Zika virus Zika virus infection [DOI] 10.1016/j.ijid.2020.09.1451 PMC 바로가기 [Article Type] Article