Effect and safety of Chinese herbal medicine granules in patients with severe coronavirus disease 2019 in Wuhan, China: a retrospective, single-center study with propensity score matching2019년 중국 우한에서 발생한 중증 코로나바이러스 질환 환자에서 한약 과립의 효과 및 안전성: 성향 점수 매칭을 통한 후향적 단일 센터 연구Article Published on 2021-05-012022-08-31 Journal: Phytomedicine : international journal of phytother [Category] 치료제, [키워드] 1:1 28-day mortality baseline category caused Chinese Chinese herbal medicine CHM Clinical improvement Computerized tomography coronavirus disease Coronavirus disease 2019 cough COVID-19 D-dimer level Day defined duration of fever Dyspnea Effect Fever fibrinolysis Granule granules Health herbal medicine high risk hospital lung lung lesion male no significant difference Ordinal Scale Patient patients treated Primary outcome propensity score matching PSM reduced retrospective Retrospective study severe coronavirus disease severe COVID-19 significant difference single-center single-center study the patient Treatment treatment effect usual care usual care alone was used Wuhan [DOI] 10.1016/j.phymed.2020.153404 PMC 바로가기 [Article Type] Article
Potential Mechanism Prediction of Herbal Medicine for Pulmonary Fibrosis Associated with SARS-CoV-2 Infection Based on Network Analysis and Molecular DockingPharmacology Published on 2021-04-122022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] analyses Analysis approach binding activity CCP Chinese Chinese herbal medicine component components contribute COVID-19 database distribution enrichment analysis exhibited expression finding Gene ontology health-care Herbal high risk IL-6 include indicated Infection inhibit involved KEGG Kyoto MAPK MAPK signaling mechanism Medicine metabolism MMP9 molecular docking molecular mechanism molecular mechanisms multiple pathways network network pharmacology offer pathway Patient Potential PPI predict prediction prescription protein-protein interaction pulmonary pulmonary fibrosis receptor SARS-CoV-2 SARS-COV-2 infection signaling pathway signaling pathways suggested target targets TGF-β1 the disease the SARS-CoV-2 TNF-α treatment for COVID-19 VEGF Version [DOI] 10.3389/fphar.2021.602218 PMC 바로가기 [Article Type] Pharmacology
Chinese Herbal Medicine Used With or Without Conventional Western Therapy for COVID-19: An Evidence Review of Clinical StudiesPharmacology Published on 2021-02-262022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 95% CI 95% confidence interval addition adverse events Analysis analyzed Characteristics Chest CT Chinese Chinese herbal medicine CHM clinical clinical study Comparator group control group control groups Controlled trial Conventional Coronavirus disease 2019 cough COVID-19 current duration of fever evaluated Evidence fatigue FIVE Herbal injection intervention group manifestation mean difference Medicine Methodological quality Negative conversion rate no statistical difference non-randomized novel coronavirus pneumonia nucleic acid test Randomized controlled trial RCT RCTs receiving reducing Retrospective study review risk risk of bia SARS-CoV-2 statistical difference tested therapeutic effect therapy therapy for COVID-19 Traditional Chinese medicine Treatment [DOI] 10.3389/fphar.2020.583450 PMC 바로가기 [Article Type] Pharmacology
Properties of the Novel Chinese Herbal Medicine Formula Qu Du Qiang Fei I Hao Fang Warrant Further Research to Determine Its Clinical Efficacy in COVID-19 TreatmentOriginal Article Published on 2021-02-012024-09-02 Journal: Medical Acupuncture [Category] 대상포진, [키워드] Chinese herbal medicine COVID-19 formula QDQF1 immune response SARS-CoV-2 Traditional Chinese medicine [DOI] 10.1089/acu.2020.1466 PMC 바로가기 [Article Type] Original Article
Chinese herbal medicine: Fighting SARS-CoV-2 infection on all frontsReview Published on 2021-01-212023-07-01 Journal: Journal of ethnopharmacology [Category] SARS, [키워드] 3CLpro, 3C-Like protease ACE2, angiotensin-converting enzyme 2 Active ingredients andro, andrographolide broad-spectrum antiviral CHIKV, Chikungunya virus Chinese herbal medicine COVID-19, Coronavirus disease 2019 EBOV, Ebola virus EC50, half maximal effective concentration FCV, feline calicivirus GA, glycyrrhizic acid GRP78, glucose regulating protein 78 H1N1, influenza A HBV, hepatitis B virus HCV, hepatitis C virus HIV, Human immunodeficiency virus HSV-1, Herpes simplex virus type 1 IC50, Half maximal inhibitory concentration IL-10, interleukin-10 JHQG, Jinhua Qinggan Granules LHQW, Lianhuaqingwen capsules Mpro, main protease MERS, Middle East respiratory syndrome coronavirus MLAV, Mengla virus NHC PRC, National Health Commission of the People's Republic of China NSP, nonstructural protein organ protection PDL, Pudilan Xiaoyan oral liquid PHEIC, Public Health Emergency of International Concern PLpro, papain-like protease RdRp, RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SARS-CoV, severe acute respiratory syndrome coronavirus SI, selectivity index TMPRSS2, Transmembrane Protease Serine 2 TNF-α, tumor necrosis factor-α WHO, World Health Organization XYP, Xiyanping injection [DOI] 10.1016/j.jep.2021.113869 PMC 바로가기 [Article Type] Review
Research Progress on Main Symptoms of Novel Coronavirus Pneumonia Improved by Traditional Chinese MedicinePharmacology Published on 2020-09-112022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] activity Anti-inflammatory antioxidant Antiviral Chinese Chinese herbal medicine Codonopsis coronavirus cough country COVID-19 COVID-19 patients diarrhea early stage fatigue Fever ginseng Gypsum IMPROVE Improved infecting initial symptom mechanism of action Medicine Mild MOST novel novel coronavirus pneumonia Patient pharmacological physiopathological mechanism Pneumonia Progress public health Radix reduce reduce mortality Research severe disease significantly spread to the patient therapeutic effects these symptoms Traditional Traditional Chinese medicine Treatment [DOI] 10.3389/fphar.2020.556885 PMC 바로가기 [Article Type] Pharmacology
5-Fluorouracil in combination with deoxyribonucleosides and deoxyribose as possible therapeutic options for the Coronavirus, COVID-19 infection코로나바이러스, COVID-19 감염에 대한 가능한 치료 옵션으로 데옥시리보뉴클레오사이드 및 데옥시리보스와 조합된 5-플루오로우라실Article Published on 2020-09-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 비임상, 치료제, [키워드] 5-Fluorouracil 5-FU animal model animal models Antiviral antiviral agent antiviral drug antiviral drugs Author breath Chinese herbal medicine Chinese herbal medicines Combination Complete coronavirus coronavirus SARS-CoV-2 COVID-19 infection COVID-19 treatment death disease drug drugs global pandemic herbal medicines Human infected patient infected patients medications Panic patients proof question removal SARS-CoV-2 term therapeutic option therapy Treatment Viral viral infection virus viruses Wuhan Wuhan, China [DOI] 10.1016/j.mehy.2020.109754 PMC 바로가기 [Article Type] Article
Potential mechanisms of Chinese Herbal Medicine that implicated in the treatment of COVID-19 related renal injuryResearch article Published on 2020-09-012022-10-05 Journal: Saudi Pharmaceutical Journal : SPJ [Category] 치료법, [키워드] Analysis Apoptosis applied association Association rules CASP3 China Chinese Chinese herbal medicine CHM clinical comparable Complication Corona COVID-19 COVID-19 infection COX1 COX2 Herbal high mortality IL6 implicated include ingredient Injury investigated kaempferol kidney mechanism Medicine modulate molecular mechanism Mortality network pharmacology NOS2 pathway Pathways Patient pharmacological Potential potential mechanism Prevent provide PTGS1 PTGS2 quercetin reduce regulate renal Renal/kidney injury reported searched shown Side effect target TCM therapeutic potential therapy TNF Traditional Chinese medicine treat Treatment Yao [DOI] 10.1016/j.jsps.2020.08.002 [Article Type] Research article
Chinese herbal medicine for COVID-19: Current evidence with systematic review and meta-analysisReview article Published on 2020-09-012022-10-05 Journal: Journal of integrative medicine [Category] SARS, 신약개발, [키워드] 95% CI 95% confidence interval Adults adverse event adverse events Analysis C-reactive protein Care changes in China Chinese Chinese herbal medicine CHM Cochrane Library collected Computed tomography contagious Continuous control group Controlled trial Course COVID-19 COVID-19 cases criteria CRP current database disease evaluator Evidence Follow-up Google Scholar hazard ratio help IMPROVE Inflammatory inflammatory markers information Infrastructure life-threatening lung CT scan marker Meta-analysis New coronavirus objective Odds ratio outcome Participants Patient peer-reviewed Pneumonia Primary outcome Randomized controlled trial RCT RCTs Result risk risk of bia SARS-CoV-2 screened searched secondary SMD standard care standardized mean difference Study design Symptom systematic review therapy time-to-event analysis Traditional Chinese medicine treat Treatment treatment group Treatment outcome was used were expressed were recorded [DOI] 10.1016/j.joim.2020.07.008 [Article Type] Review article
A systematic review and meta-analysis of the efficacy and safety of western medicine routine treatment combined with Chinese herbal medicine in the treatment of COVID-194900 Published on 2020-08-072022-10-30 Journal: Medicine [Category] COVID-19, MERS, [키워드] 2019-nCoV adverse events Adverse reactions assist Blood CBM China Chinese Chinese herbal medicine CNKI Cochrane Library Complete Coronavirus disease 2019 COVID-19 data extraction effective Efficacy and safety eight evaluate Evidence Fatality rate Fever global public health Infectious disease lack Meta-analysis patient hospitalization peer-reviewed Pneumonia Prevent Primary outcome protocol Registration Research risk of bia secondary outcome Support symptomatic Symptoms systematic review therapy Traditional Chinese medicine Treatment VIP virus nucleic acid Western medicine [DOI] 10.1097/MD.0000000000021616 PMC 바로가기 [Article Type] 4900