Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registryArticle Published on 2022-08-152022-11-16 Journal: Respiratory Research [Category] SARS, 치료기술, [키워드] adjusted Affect Analysis antiplatelet association Atherosclerosis baseline baseline characteristics cardiovascular disease cardiovascular risk Characteristics chronic chronic obstructive COPD COVID COVID-19 COVID-19 pandemic Diagnosis discharge dissimilarity Impact In-hospital In-hospital death independent International Mortality multicenter Myocardial infarction Obstructive occurred outcome outcomes pandemic pathophysiological mechanism Patient patients Percutaneous coronary intervention prognostic proportion pulmonary disease SARS-CoV-2 positivity significant difference significantly significantly higher STEMI subject therapy treated two groups [DOI] 10.1186/s12931-022-02128-0 PMC 바로가기
Multi-disciplinary community respiratory team management of patients with chronic respiratory illness during the COVID-19 pandemicObservational Study Published on 2022-08-132022-10-04 Journal: NPJ Primary Care Respiratory Medicine [Category] 임상, 치료법, [키워드] Admission Admissions analysed benefit carried chronic obstructive chronic respiratory chronic respiratory disease Community correlated COVID-19 pandemic death Electronic health record highest Hospital admission implementation Infection Interaction Linear regression management Mortality NHS nosocomial COVID-19 occurred outcome pathway Pathways Patient Poisson model proportion pulmonary disease Rate reducing reduction in respiratory response secondary care severity significant decrease significantly higher team Triage Trust [DOI] 10.1038/s41533-022-00290-y PMC 바로가기 [Article Type] Observational Study
Hypocalcemia: A key biomarker in hospitalized COVID-19 patientsResearch article Published on 2022-08-012022-10-05 Journal: Biomedical journal [Category] SARS, 바이오마커, [키워드] addition Admission adult subject Arterial hypertension association Biochemical biomarkers Biomarker blood biochemical calcium calcium concentration Cancer cardiovascular diseases China Chronic diseases Chronic kidney disease chronic obstructive CKD clinical complication Cohort collected Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients CVD diabetes effective enrolled evaluated hospital hospitalizations hospitalized COVID-19 patient Hypocalcemia identify indicated ionized calcium mandatory material mechanical ventilation obesity outcome parameter Pathologies pathology patients poor prognosis positive correlation presence of comorbidity Previous studies profile Prognosis prognostic biomarker pulmonary disease Result SARS-CoV2 serum severity syndrome the disease [DOI] 10.1016/j.bj.2022.08.005 [Article Type] Research article
Efficacy of salmeterol and magnesium isoglycyrrhizinate combination treatment in rats with chronic obstructive pulmonary disease Research Published on 2022-07-192022-10-05 Journal: Scientific Reports [Category] 바이오마커, 치료제, [키워드] Adverse reaction airway Anti-inflammatory Bronchoalveolar lavage fluid characterized chronic inflammation chronic obstructive Clinical treatment Combination combination treatment contributing to COPD glucocorticoid Hormones IL-1β IL-6 infiltration inflammatory cell involved JAK/STAT signaling pathway Lung function Lung inflammation Lymphocytes Magnesium isoglycyrrhizinate mechanism MUC5AC neutrophil Patient propionate pulmonary disease receptor reduced salmeterol xinafoate secretion serum steroidal anti-inflammatory drugs suggested TNF-α Treatment White blood cells [DOI] 10.1038/s41598-022-16775-2 [Article Type] Research
Lp-PLA2 as a biomarker and its possible associations with SARS-CoV-2 infection바이오마커로서의 Lp-PLA2 및 SARS-CoV-2 감염과의 가능한 연관성Review Published on 2022-07-012022-09-11 Journal: Biomarkers in Medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] affected association Biomarker Biomarkers cardiovascular condition cardiovascular conditions chromosome chronic obstructive chronic obstructive pulmonary disease COVID-19 Economy enzyme estimation Evidence Exercise Tolerance healthy individuals help hepatic disease hour Inflammation life Lp-PLA2 management marker metabolic condition metabolic conditions obstructive pulmonary disease oxidative stress pathophysiological Pathways PLA2G7 pulmonary disease renal impairment risk SARS-COV-2 infection Serum level serum levels Sickness Signal transduction Tolerance Treatment [DOI] 10.2217/bmm-2021-1129 PMC 바로가기 [Article Type] Review
RT- PCR testing of upper respiratory tract samples for diagnosis of SARS-CoV-2: Between justification and overestimation, a multi-center international studySARS-CoV-2 진단을 위한 상기도 샘플의 RT-PCR 검사: 정당화와 과대평가 사이, 다기관 국제 연구Multicenter Study Published on 2022-07-012022-09-11 Journal: Travel medicine and infectious disease [Category] COVID19(2023년), SARS, 치료기술, [키워드] affected Analysis bilateralism Binary logistic regression binary logistic regression analysis chain Chain Reaction chronic obstructive chronic obstructive pulmonary disease clinical care collected conversion Conversion time COVID COVID 19 COVID 19 patient COVID-19 Critical detectable determine Diagnosis effective elevated erythrocyte sedimentation erythrocyte sedimentation rate Factor Factors false false-negative false-negative results Fever headache Health Hospitalized hospitalized patient hypertension identifying incidence independent risk factor independent risk factors infectious initial interfere International Isolation likelihood lobe lobes lymphopenia median negative RT-PCR obstructive pulmonary disease Occurrence outcome Patient patients polymerase chain reaction positive positive RT-PCR pulmonary disease radiological reaction RT- PCR RT-PCR SARS-CoV-2 RNA sedimentation rate tested upper respiratory tract [DOI] 10.1016/j.tmaid.2022.102334 PMC 바로가기 [Article Type] Multicenter Study
Effect of modified Total Body Recumbent Stepper training on exercise capacity and thioredoxin in COPD: a randomized clinical trial Research Published on 2022-07-012022-10-05 Journal: Scientific Reports [Category] 임상, [키워드] acute exacerbation alleviate benefit Body Borg chronic obstructive control group COPD Dyspnoea Effect exercise Exercise capacity exercise intolerance exhibited Follow-up groups Guidance increase in indication Intervention mechanism mMRC mRNA expression no difference oxidative stress parameter Patient patients Protein pulmonary disease Pulmonary function pulmonary rehabilitation randomized clinical trial randomly divided reduce reduced rehabilitation significantly increased Spinal cord injury Stepper stroke Symptom Total undergo walking distance [DOI] 10.1038/s41598-022-15466-2 [Article Type] Research
Association of epicardial adipose tissue with the severity and adverse clinical outcomes of COVID-19: A meta-analysisReview article Published on 2022-07-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 바이오마커, 임상, [키워드] 95% confidence interval adipose Adiposity Adverse adverse outcome chronic obstructive CIs Clinical outcome Computed tomography Control Coronary artery disease COVID-19 COVID-19 severity database diabetes Effect Epicardial adipose tissue help Hospitalization independent intensive care Invasive mechanical ventilation mean difference measure Meta-analysis objective Patient patients with COVID-19 poor prognosis positive primary end point Prognosis prognostic risk stratification pulmonary disease Quantitative Result risk factor Risk factors searched severe group severity SMD tissue visceral [DOI] 10.1016/j.ijid.2022.04.013 [Article Type] Review article
Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics녹농균(Pseudomonas aeruginosa): 병인, 독성 인자, 항생제 내성, 숙주와의 상호 작용, 기술 발전 및 새로운 치료법Review Published on 2022-06-252022-09-11 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, MERS, 유전자 메커니즘, [키워드] addition Antibiotic resistance Antibiotics antimicrobial autophagy Bacterial Bacterial pathogenesis bioinformatics burn wounds Cancer caused Cell signaling cGAS chronic obstructive clinically COPD COVID-19 CRISPR CRISPR-Ca cystic fibrosis Defense develop disorder drug drug resistance Drug screening effective effort Factor Factors fibrosis gram Host host defense host immune responses host-pathogen interaction immune immune responses immunodeficiency IMPROVE infect Infection infections Inflammasome Interaction intractable invasive LPS mammalian cell mechanism metabolomics molecular Non-coding RNAs opportunistic pathogen outer membrane P. aeruginosa pathogen Pathogenesis Pathways Patient platform Pseudomona Pseudomonas aeruginosa rapid progress Regulation Research scRNA-seq secretion Severe infection signaling pathways Strains therapy traits treat use of antibiotics Ventilation Vesicle virulence widespread [DOI] 10.1038/s41392-022-01056-1 PMC 바로가기 [Article Type] Review
Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease유전 및 염증성 기도 질환에서 글리코사미노글리칸의 표적화Review Published on 2022-06-082022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, 진단, [키워드] addition airway alveolar epithelium Asthma Cell cell differentiation chronic obstructive chronic obstructive pulmonary disease contribute COVID-19 COVID-19 pandemic cystic fibrosis described Diseases ECM Endothelium Extracellular matrix fibrosis glycosaminoglycan glycosaminoglycans Immune cell infiltration Inflammation Inflammatory Interaction interstitial involved lung Migration molecular interaction pathology pathophysiological role pulmonary disease receptor Research Respiratory disease targeting therapeutic agents tissue wound healing [DOI] 10.3390/ijms23126400 PMC 바로가기 [Article Type] Review