A Knowledge, Attitude, and Perception Study on Flu and COVID-19 Vaccination during the COVID-19 Pandemic: Multicentric Italian Survey InsightsArticle Published on 2022-01-192022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Affect Attitude Attitudes Chinese health authority clinical conditions Comorbidity conducted confirmed case COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional death Diseases evaluated Factors First wave FIVE flu vaccination General population higher risk humans immunization impacts IMPROVE Influenza insight Intention Italian Italy knowledge knowledge score lack morbidity Mortality multicenter Novel coronavirus pandemic participant Perception problem questionnaire reason receive SARS-COV-2 infection Side effect significantly Spread study period survey susceptibility the disease the vaccine unlikely vaccinated against COVID-19 vaccination Vaccine virus was collected [DOI] 10.3390/vaccines10020142 PMC 바로가기 [Article Type] Article
Pulmonary Mesenchymal Stem Cells in Mild Cases of COVID-19 Are Dedicated to Proliferation; In Severe Cases, They Control Inflammation, Make Cell Dispersion, and Tissue RegenerationImmunology Published on 2022-01-132022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] “cytokine storm” affected Alter Analysis biological function bronchoalveolar lavage sample CD40 Cell cell proliferation Cell therapy cell types chemotaxis clinical conditions Control COVID-19 COVID-19 patient Cytokine storm cytoplasmic Data analysis dispersion FHL2 Genes IFNGR1 IFNGR2 immune individual individuals induce inhibitor involved lung marker MDA5 mesenchymal stem cell Mild mild case mild COVID-19 patients MSC MSCs Necrosis NF-κB NFKBIA not express OPTN overexpression paracrine Patient performed PKR PPP2CB promote inflammation pulmonary receptors regeneration RNA secretion sequence Severe case severe COVID-19 single cell RNA sequencing single-cell RNA-seq STEM stem cell Target genes therapeutic therapeutic potential therapy for COVID-19 these cell tissue tlr-3 TLRs TNFR1 TNFR2 Transcription transcriptionally treat triggered upregulated upregulated gene upstream virus virus load [DOI] 10.3389/fimmu.2021.780900 PMC 바로가기 [Article Type] Immunology
Immunoediting in SARS-CoV-2: Mutual relationship between the virus and the hostReview Published on 2022-01-102022-10-04 Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome adaptive immune system Cancer Cancer cells caused clinical conditions coronavirus Coronavirus disease 2019 Course COVID-19 develop disease early infection effective effort Epitopes growth hallmark help heterogeneous HIV Host HTLV-1 immune response immune system in viral infected cell infected cells Inflammatory response inhibiting malignancy MHC I molecule modulating Mutation occur pathophysiological mechanism patients promote response SARS-CoV-2 suppresse the interferon the SARS-CoV-2 therapeutic strategy tumor cell untreated patients viral infection virus [DOI] 10.1016/j.intimp.2022.108531 PMC 바로가기 [Article Type] Review
Management skin manifestation of multisystem inflammatory syndrome associated with SARS-CoV-2SARS-COV-2와 관련된 다중 시스템 염증 증후군의 관리 피부 증상Case Reports Published on 2022-01-062022-09-01 Journal: Virology Journal [Category] 진단, [키워드] A multisystem inflammatory syndrome Affect Antibiotics Brain children clinical conditions Contact COVID-19 COVID-19 infection Dermatology described develop Diagnosis discharged disease effective emergency department Europe eyes Fever headache high fever Hospitalization Immunoglobulin indicated infected with SARS-CoV-2 Infection Inflammatory Initially intravenous Intravenous immunoglobulin IVIG joint joint pain kidney Laboratory laboratory findings lung male Methylprednisolone MIS MIS-C morbidity and mortality nausea organ Pain Paracetamol Patient pulse radiological reducing SARS-CoV-2 skin skin lesion skin lesions syndrome tissue inflammation Treatment USA weakness with COVID-19 [DOI] 10.1186/s12985-021-01736-4 PMC 바로가기 [Article Type] Case Reports
Vitamin D: Dosing, levels, form, and route of administration: Does one approach fit all?Article Published on 2021-12-232022-10-28 Journal: Reviews in Endocrine & Metabolic Disorders [Category] COVID-19, SARS, [키워드] administration affecting appear approach bone clinical conditions condition Conference COVID-19 deficiency Diabetes Mellitus different disease Dosing Extraskeletal effects General population Glucocorticoids greater healthy indicated International International Conference kidney liver management mechanism metabolism obesity Osteoporosis outcomes parathyroid hormone Parenteral Patient populations SARS-COV-2 infection skeletal Specific syndrome therapeutic to define treated Vitamin Vitamin D vitamin D administration vitamin D level Vitamin D supplementation [DOI] 10.1007/s11154-021-09693-7 PMC 바로가기 [Article Type] Article
Challenges posed by COVID‐19 in cancer patients: A narrative reviewReview Published on 2021-12-232022-10-31 Journal: Cancer Medicine [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] acute respiratory syndrome Affect affected Cancer cancer patient challenge Chemotherapy clinical conditions Clinical management coronavirus coronavirus disease COVID‐19 COVID‐19 infection COVID‐19 develop diagnosing effort Evidence General population group helping higher risk immune system immunocompromised condition immunodeficiency IMPROVE increase International malignancy management Novel coronavirus outcome pandemic Patient patients profiles Prognosis public health emergency risk risk of infection SARS‐CoV‐2 SARS‐CoV‐2 treated World Health Organization [DOI] 10.1002/cam4.4519 PMC 바로가기 [Article Type] Review
Prospective, observational, single-centre cohort study with an independent control group matched for age and sex aimed at investigating the significance of cholinergic activity in patients with schizophrenia: study protocol of the CLASH-studyArticle Published on 2021-12-202022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] acetylcholinesterase addition adult psychiatry age and sex alteration anticipated approach approval association Butyrylcholinesterase calculated carried changes clinical clinical conditions clinical symptom code cognitive cognitive disorders cohort study control group Critically ill patient delirium delirium & Department disorders duration of illness enrolment esterase Ethics Evidence extension form Germany Hospital admission Hypothesis independent metabolism negative Neuroinflammation Observational cohort study parameter pathophysiological Patient point-of-care Prospective psychotherapy psychotic disorders. Registered required Sample size SARS-CoV-2 pandemic scale Schizophrenia schizophrenia & schizophrenic Secondary objective statistical analysis Study protocol Symptom the ethics committee Ulm university [DOI] 10.1136/bmjopen-2021-050501 PMC 바로가기 [Article Type] Article
Pandemic hospitals and reorganizing emergency departmentsArticle Published on 2021-12-172022-10-29 Journal: Turkish Journal of Medical Sciences [Category] COVID-19, SARS, [키워드] airway Cardiopulmonary city clinical conditions condition conditions Contact COVID-19 pandemic COVID-19 pandemics diagnosing Diagnosis Disasters Disruption Emergencies emergency department emergency treatment facilitated follow-up period health institution Health Service healthcare hospital Hospitalization Hospitalized hospitals Intensive intensive care Isolation Laboratory management Measures medical services occur Outpatient pandemic Patient Patient care patients physical provided Stage Support symptoms of COVID-19 the disease the patient treated Turkey [DOI] 10.3906/sag-2106-169 PMC 바로가기 [Article Type] Article
COVID-19 and obesity: a systematic review and meta-analysis on the pre-existing clinical conditions, COVID-19 symptoms, laboratory findings and clinical outcomesLetter to the Editor Published on 2021-12-022022-10-31 Journal: EXCLI Journal [Category] COVID-19, [키워드] clinical conditions Clinical outcome COVID-19 COVID-19 symptoms Laboratory Meta-analysis systematic review [DOI] 10.17179/excli2021-4226 PMC 바로가기 [Article Type] Letter to the Editor
Drug repurposing in COVID-19: A review with past, present and futureResearch article Published on 2021-12-012022-10-05 Journal: Metabolism Open [Category] 신약개발, 임상, 치료제, [키워드] ACE2 Applying approach approaches approved cause clinical conditions clinical trials conducted coronavirus disease coronavirus SARS-CoV-2 COVID-19 COVID-19 disease COVID19 drug Drug repurposing effective Effectiveness ENCODE Favipiravir FDA food Genome global public health host cell surface identify in vitro infection process initiate Interaction molecular docking problems protease inhibitors Protein Protein structure‐based drug design Remdesivir reuse ribavirin Ritonavir RNA virus SARS CoV2 SARS-CoV2 shown single-stranded positive-sense spike structural proteins therapeutic agent Tocilizumab treat [DOI] 10.1016/j.metop.2021.100121 [Article Type] Research article