Protocol for a phase 3 trial to evaluate the effectiveness and safety of a heterologous, two-dose vaccine for Ebola virus disease in the Democratic Republic of the Congo콩고민주공화국에서 에볼라 바이러스 질병에 대한 이종 2회 용량 백신의 효과와 안전성을 평가하기 위한 3상 시험 프로토콜Article Published on 2022-03-082022-09-11 Journal: BMJ Open [Category] 비임상, [키워드] Ad26 animal board breath children clinical examination clinical trial collected conducted conferences COVID-19 Democratic Republic determine disease dose doses Ebola Ebola virus Ebola virus disease Effectiveness eligible adult Eligible adults ELISA enrolled Ethics ethics committee evaluate Filovirus finding glycoprotein group group discussion health problem Heterologous immune response immune responses Infant Infectious diseases offered Open Access Open-label outbreak participant Participants phase 3 trial Pregnancy Prophylactic public health recorded reduce regimen registration number Research review SAE SAEs Sample second dose Serious Adverse Event Serious Adverse Events sub-Saharan Africa subset tested Trial tropical tropical medicine vaccination Vaccinations Vaccine vaccinia virus Virus Disease virus transmission were given women [DOI] 10.1136/bmjopen-2021-055596 PMC 바로가기 [Article Type] Article
Online consultation in an orthopedic trauma surgery outpatient clinic: is there a learning curve?Research Published on 2022-03-022022-10-27 Journal: BMC Musculoskeletal Disorders [Category] Coronavirus, MERS, SARS, [키워드] accounted category clinical examination Cohort condition connection Contact COVID-19 COVID-19 pandemic Effectiveness feasibility Follow-up Follow-up visit implementation lifted lockdown maintain no difference Online consultation orthopedic outcome outpatient clinic Patient Patient care patients Physical examination pilot study Result resulting significant difference Support surgical Telemedicine therapy this system took place trauma Treatment Volume was used were recorded while [DOI] 10.1186/s12891-022-05144-9 PMC 바로가기 [Article Type] Research
Lung ultrasound in ruling out COVID-19 pneumonia in the ED: a multicentre prospective sensitivity studyObservational Study Published on 2022-03-012022-10-05 Journal: Emergency medicine journal : EMJ [Category] SARS, 임상, [키워드] 95% CI 95%CI Accuracy Blood clinical examination cough COVID-19 COVID-19 outbreak CXR diagnosed diagnosing Diagnosis diagnosis of COVID-19 diagnostic emergency department enrolled Fever Italy likelihood ratio multicentre Negative predictive value pathway Patient patients Pneumonia positive Positive predictive value Pragmatic Prevalence prospective observational study protocol radiological Real-time PCR reference standard Research SARS-CoV-2 sensitivity Shortness of breath specificity Spread Symptom Symptoms the patient Ultrasonography [DOI] 10.1136/emermed-2020-210973 PMC 바로가기 [Article Type] Observational Study
Medical students from German-speaking countries on abroad electives in Africa: destinations, motivations, trends and ethical dilemmasResearch Published on 2022-01-172022-10-31 Journal: Human Resources for Health [Category] Coronavirus, SARS, [키워드] Africa analyzed categories chose clinical examination country database driving East engage Europe Factor feasible Germany global health highlight IMPROVE International International elective investigated knowledge literature medical education Medical elective medical ethics Overseas elective proportion reported Result SARS-CoV-2 School selected South Africa student surgery Surgical Procedure Travel Travel medicine unique [DOI] 10.1186/s12960-022-00707-2 PMC 바로가기 [Article Type] Research
The Impact of COVID-19 Pandemic on the Learning Outcomes of Medical Students in Taiwan: A Two-Year Prospective Cohort Study of OSCE PerformanceArticle Published on 2021-12-252022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] average clinical examination COVID-19 COVID-19 pandemic distal evaluate Final groups had more Impact learning medical students National no significant difference OSCE (objective structured clinical examination) outcome pandemic performance Prospective significantly standardized patient student supplemental teaching while [DOI] 10.3390/ijerph19010208 PMC 바로가기 [Article Type] Article
Rehabilitation needs following COVID-19: Five-month post-discharge clinical follow-up of individuals with concerning self-reported symptomsResearch article Published on 2021-12-052022-10-05 Journal: EClinicalMedicine [Category] 임상, [키워드] affective Analysis auditory breathlessness clinical examination clinically cognitive Cognitive function Cognitive impairment Cohort cohort study complexity concerning Consequences COVID-19 detrimental fatigue finding FIVE Follow-up form functional healthcare hospital hospitalised patient hospitalized COVID-19 patient individual Intervention Linköping Long-term follow-up nonspecific Östergötland PACS Pain Patient performed post-COVID-19 primary care problem provided Region regions rehabilitation Rehabilitation need reported required Residual symptoms SARS-CoV-2 self-reported symptom survivor Swedish Symptom Symptoms translated weakness were assessed [DOI] 10.1016/j.eclinm.2021.101219 [Article Type] Research article
Study protocol for a randomized clinical trial to evaluate the effect of the use of Xylitol gum in the prevention of caries lesions in children living in Ladakh—the Ca ries Pre vention X ylitol in Ch ildren (CaPreXCh) trialLadakh에 거주하는 어린이의 우식 병변 예방에 대한 자일리톨 검 사용의 효과를 평가하기 위한 무작위 임상 시험의 연구 프로토콜 - 어린이의 Caries Prevention X ylitol(CaPreXCh) 시험Study Protocol Published on 2021-12-042022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] administration afternoon Analysis baseline bleeding calculated caries cariogenic bacteria carried chewing gum children clinical clinical examination clinical trial conducted COVID-19 pandemic Cox regression Data analysis dental plaque dentinal Efficacy enamel evaluate evaluate the effect Evidence frailty Health help India initial Ladakh lesion Maltitol moderate morning oral examination oral health parallel-group participant pellet plaque Prevalence prevention programmes Primary outcome protocol Randomized randomized clinical trial Randomly receive recorded reduce repeated reported subject sucrose supplementary material sweetener Trial triple-blind two groups Valley w/v Xylitol [DOI] 10.1186/s13063-021-05828-y PMC 바로가기 [Article Type] Study Protocol
Implementing Lung Ultrasound in the Outpatient Management of COVID-19 Pneumonia: A Pilot Study to Update Local GuidelinesMedicine Published on 2021-11-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age ambulatory patient approach assessment calculated chest X-ray clinical examination clinician conducted COVID-19 COVID-19 pandemic demographics Descriptive statistics Diagnosis died distribution evaluate Follow-up guideline help Hospitalization Hospitalized Implementing IMPROVE Inclusion Local lung management means men Mild-to-moderate outcome Outpatient pandemic Patient percentages performed Pneumonia presenting Prospective Study protocol random reduce SARS-CoV2 Sensitivity and specificity severity and prognosis single-center Standard deviation Switzerland Ultrasound variables with COVID-19 [DOI] 10.3389/fmed.2021.774035 PMC 바로가기 [Article Type] Medicine
Improving the early identification of COVID-19 pneumonia: a narrative reviewCOVID-19 폐렴의 조기 식별 개선: 서술적 검토Review Published on 2021-11-012022-09-11 Journal: BMJ Open Respiratory Research [Category] SARS, 치료기술, [키워드] Admissions Altered mental status Asymptomatic Bacterial bacterial pneumonia basic biochemical blood pressure carried Chest chest X-ray clinical examination clinical parameter Clinical parameters Community Confusion Contact contribute COVID-19 COVID-19 case COVID-19 disease COVID-19 patient COVID-19 pneumonia COVID-19 pneumonia patient COVID-19 pneumonia patients COVID-19 progression CRP Delayed Deterioration Disease progression duration of symptom Dyspnoea early disease Evidence evidence of facilitate fatigue feasible Fever healthcare Hospital admissions hypoxia identifying IMPROVE Improving increase intervene Intervention less limit literature review MONITOR morbidity Mortality oxygen oxygen saturation oxygen saturations parameter Patient persistent fever Pneumonia Predictive Prevent Prognosis progression progressive COVID-19 proportion Pulmonary embolism pulse question respiratory infection respiratory rate risk Sepsis severe disease severe fatigue Shortness of breath Symptom temperature the disease the timing threshold thresholds utility [DOI] 10.1136/bmjresp-2021-000911 PMC 바로가기 [Article Type] Review
MOG antibody-associated encephalitis secondary to Covid-19: case reportCOVID-19에 이차적 인 MOG 항체 관련 뇌염 : 사례보고Case Reports Published on 2021-10-272022-09-01 Journal: BMC Neurology [Category] 진단, [키워드] Affect affecting Analysis antibody Antibody titer Antibody titre association Atypical Autoimmunity brain MRI Case report cerebrospinal fluid clinical examination CNS Course COVID-19 COVID-19 infection CSF Deterioration Encephalitis executive full recovery headache highlight in some include Infection Inflammation Laboratory laboratory examination lesion male manifestation Methylprednisolone MOG MOG antibody MRI neurological manifestation neurological manifestations Neuropsychology occur outcome Patient patients PCR Prognosis respiratory Respiratory system SARS-CoV-2 serum the disease Treatment unique while [DOI] 10.1186/s12883-021-02449-5 PMC 바로가기 [Article Type] Case Reports