Severe acute respiratory syndrome coronavirus 2 antibody prevalence in adult patients with short bowel syndrome-A German multicenter cross-sectional study성인 단장증후군 환자에서 중증급성호흡기증후군 코로나바이러스 2 항체 유병률-독일 다기관 횡단면 연구Multicenter Study Published on 2022-08-012022-09-11 Journal: JPEN. Journal of parenteral and enteral nutrition [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody test Antigen asked assumed avoidance bowel Care comparable complexity concerning Contact contact with coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 disease COVID-19 infection cross-sectional Definition disease Economy Effect fill out Frequency Germany group Hospitalized increased risk Infection less median Mild multicenter N protein National no difference nucleocapsid parenteral nutrition Patient patients positive Prevalence questionnaire receiving respiratory risk risk behavior risk factor SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Short bowel syndrome short bowel syndrome (SBS). syndrome tertiary care center the patient Treatment [DOI] 10.1002/jpen.2410 PMC 바로가기 [Article Type] Multicenter Study
Availability of oral antivirals against SARS-CoV-2 infection and the requirement for an ethical prescribing approachSARS-CoV-2 감염에 대한 경구 항바이러스제의 가용성 및 윤리적 처방 접근의 요구 사항Review Published on 2022-08-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] Fulltext, SARS, 변종, 치료제, [키워드] Antiviral antivirals approach authorisation complexity condition conducted country COVID-19 draft drug Effectiveness Efficacy FIVE health system health systems hierarchy high risk indicated Medicine Mild-to-moderate molnupiravir national health authorities national health authority Nirmatrelvir non-hospitalised Omicron variant Patient patients with COVID-19 placebo-controlled Policy predicted Randomised trial Ritonavir SARS-CoV-2 SARS-COV-2 infection scoring system severe COVID-19 supported symptom onset Transparency treat USA [DOI] 10.1016/S1473-3099(22)00119-0 PMC 바로가기 [Article Type] Review
Drug repurposing based on a quantum-inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2고전적 지문과 비교하여 양자에서 영감을 받은 방법을 기반으로 한 약물 용도 변경은 SARS-CoV-2에 대한 잠재적인 항바이러스제를 밝혀냅니다.Article Published on 2022-07-182022-09-11 Journal: PLoS Computational Biology [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] accelerated Algorithm Alpha Antiviral antiviral therapeutics approach approved B.1.1.7 B.1.351 B.1.617.2 Beta binary BMS-986094 Cell culture classical cobalamin Combination comparison Comparisons complex complexity Compound compounds computational resource computational resources COVID-19 pandemic cytotoxicity Delta demonstrated Drug repurposing DrugBank database Efficacy England evaluate form GS-6620 IC50 identify in vitro inhibit inhibited inhibitors inhibitory concentration limit maximum optimization overlap pace parameter predicted problem RdRP Remdesivir replication of SARS-CoV-2 resolved RNA-dependent RNA polymerase SARS-CoV-2 SARS-COV-2 infection screening method several variant several variants strain these compound these compounds vitamin B12 while [DOI] 10.1371/journal.pcbi.1010330 PMC 바로가기 [Article Type] Article
Vulture-Based AdaBoost-Feedforward Neural Frame Work for COVID-19 Prediction and Severity Analysis SystemVulture-Based AdaBoost-Feedforward Neural Frame Work for COVID-19 예측 및 심각도 분석 시스템Article Published on 2022-06-012022-09-11 Journal: Interdisciplinary sciences, computational life sci [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy affected Affected part tracking Analysis chest X-ray Chest X-ray image Chest X-ray images complexity COVID COVID-19 COVID-19 disease COVID-19 severity death deep learning develop disease early stage error rate Feature extraction human body humans identify initial involved machine learning mechanism Neural offer prediction reduce required Research researcher risk Segmentation severity Severity analysis. spread of COVID-19 System virus Vulture work X-ray [DOI] 10.1007/s12539-022-00505-3 PMC 바로가기 [Article Type] Article
Novel mobility index tracks COVID-19 transmission following stay-at-home orders새로운 이동성 지수는 재택 명령에 따른 COVID-19 전염을 추적합니다.Article Published on 2022-05-102022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Additive Model adjusted average change complexity COVID-19 COVID-19 case COVID-19 cases COVID-19 transmission defined effective expiration explained functional Hierarchical index individual Interaction interactions Metrics mitigate Mobility monitoring multidimensional novel population density Principal component principal component analysis public health reduction SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants significantly Spread Vaccine Variability vulnerability while with COVID-19 [DOI] 10.1038/s41598-022-10941-2 PMC 바로가기 [Article Type] Article
Improved methods for the detection and quantification of SARS-CoV-2 RNA in wastewater폐수에서 SARS-CoV-2 RNA의 검출 및 정량화를 위한 개선된 방법Article Published on 2022-05-032022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] aluminum aluminum hydroxide buffer complexity Concentration confirmed cases coronavirus correlation COVID-19 pandemic detect enveloped virus epidemiological data genetic material glycine hydroxide Improved lack matrix mengovirus methodology N1 and N2 organic matter positive Precipitation problems produced quantification quantity reduction SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection selected targets virus wastewater [DOI] 10.1038/s41598-022-11187-8 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease OutcomesSARS-CoV-2 점 돌연변이 및 삭제 스펙트럼과 다양한 질병 결과와의 연관성Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, [키워드] Amino acid amino acid substitution amino acid substitutions Amplicon amplicons Analysis association average complexity consensus sequence coronavirus COVID-19 COVID-19 pandemic COVID-19 severity Deletion deletions develop diagnostic disease diversity index Effects functional Genetic variant genetic variants Haplotype infected patients isolate isolates location Mild mild COVID-19 symptoms Mild disease Mild symptom mild symptoms moderate moderate or severe disease mutant mutant spectra mutant spectrum Mutation mutations nasopharyngeal Nsp12 nsp12 (polymerase) Patient patients with moderate phenotypic Point Point mutation polymerase Region RNA RNA virus RNA viruses SARS-CoV-2 selective pressures Sequencing severe COVID-19 severe disease severity significantly significantly higher Spain spike three-dimensional structure ultradeep sequencing. viral pathogenesis virus [DOI] 10.1128/spectrum.00221-22 PMC 바로가기 [Article Type] Article
Types and Applications of Nicking Enzyme-Combined Isothermal AmplificationNicking 효소 결합 등온 증폭의 유형 및 응용Review Published on 2022-04-212022-09-11 Journal: International Journal of Molecular Sciences [Category] 진단, 치료제, [키워드] amplification amplify application biochemical cleavage clinics Community complexity COVID-19 diagnostic diagnostics Disadvantages Efficiency enzyme Enzymes hospitals Immunodiagnosis IMPROVE Intensive isothermal isothermal amplification limitations molecular molecular detection Molecular diagnosis Nicking nicking enzyme. nucleic acid nucleic acids outbreak overcome platform POCT point-of-care Research shown subject target targets temperature Type [DOI] 10.3390/ijms23094620 PMC 바로가기 [Article Type] Review
Passivated Impedimetric Sensors for Immobilization-Free Pathogen Detection by Isothermal Amplification and Melt Curve Analysis등온 증폭 및 용융 곡선 분석에 의한 고정화 없는 병원체 검출을 위한 부동태화 임피던스 센서Article Published on 2022-04-202022-09-11 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis Automation Clinical diagnosis complexity Curve detection Diagnosis diagnostic driven by false impedance increase isothermal amplification Laboratory LAMP Loop-mediated isothermal amplification Melt melt curve analysis microheating MONITOR pathogen detection POC point-of-care raise reduce robust SARS-CoV-2 pandemic Scaling sensor significantly true-positive Validity virus virus detection [DOI] 10.3390/bios12050261 PMC 바로가기 [Article Type] Article
Research progress in laboratory detection of SARS-CoV-2SARS-CoV-2의 실험실 검출 연구 진행Review Published on 2022-04-012022-09-11 Journal: Irish Journal of Medical Science [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] advancement analyzed antibody Antibody detection can not Characteristics clinical samples Complete complexity detection efficiency Detection sensitivity diagnosing Diagnosis disadvantage Disadvantages Efficiency false-negative false-negative results help highest Increases Laboratory Laboratory detection NCBI New coronavirus Nucleic acid detection nucleic acid testing nucleocapsid protein primer Primers Probability provided qRT-PCR ranged reported required Research SARS-CoV-2 SARS-CoV-2 detection SARSCoV-2 Serological detection target viral infection virus was used [DOI] 10.1007/s11845-021-02604-4 PMC 바로가기 [Article Type] Review